View Full Version : Day 5 on Wellbutrin SR - My mind is blank


LaVieEnRose
06-10-11, 07:03 PM
...to the point that trying to think of what to write in this thread isn't easy. :eek:

Has anyone experienced this? It's significant. I started noticing it at about day 3.. ****! I can't even write this opening post! I can't think. Seriously.

I was talking to a friend earlier and I wasn't fluent with my speech. We were trying to make plans and it was just.. *really* difficult. Ugh. I'm ****ed.

AddaptAbilities
06-10-11, 08:58 PM
I've experienced this. Not with Wellbutrin, which made me aggressive, but with Lexapro. The only thing I could do was sit on the couch. If the med didn't also make me hungry, I wouldn't even have eaten, and as it was trying to obtain/prepare food was a monumental chore.

I'd call your pdoc.

buddy
06-10-11, 09:08 PM
I too have experienced this.Not on Wellbutrin but on Pamelor.I don't know why this happens but I would certainly call your doctor.Hang in there & good luck.

Hathor
06-11-11, 04:13 AM
...to the point that trying to think of what to write in this thread isn't easy. :eek:

Has anyone experienced this? It's significant. I started noticing it at about day 3.. ****! I can't even write this opening post! I can't think. Seriously.

I was talking to a friend earlier and I wasn't fluent with my speech. We were trying to make plans and it was just.. *really* difficult. Ugh. I'm ****ed.

yes I am on day 18 of Welbutrin XL and have the same problem in a big way. Like you I noticed it about day 3. it seemed to peak about day 7-10, then it started going away. On day 14 it was still there a bit, but then I increased the dose from 150mg to 300, and it came back just as bad as ever. But it seems to be fading fast, I feel much better today.

Today (day 18) I had my first definite beneficial response, I cleaned up after I made supper and I didn't mind it, and was really fast and efficient. Def not my imagination. Not any help with mood yet though.

Also I noticed this problem comes up fairly regularly on the depression forums welbutrin section, but unfortunately nearly all the people who posted about the symptom dont come back to say if it went away or not

Impromptu_DTour
06-11-11, 10:00 AM
...to the point that trying to think of what to write in this thread isn't easy. :eek:

Has anyone experienced this? It's significant. I started noticing it at about day 3.. ****! I can't even write this opening post! I can't think. Seriously.

I was talking to a friend earlier and I wasn't fluent with my speech. We were trying to make plans and it was just.. *really* difficult. Ugh. I'm ****ed.

Im taking 150 XRs (supposed to be twice a day but ive dropped my dose). Ive had this with wellbutrin. I mean.. it sounds largly like an adjustment period thing. It has only been day three.. and this is what welbutrin does.

in essense it makes you overload on Dopamine, and Norepinephrine. It does this by cutting off how much of those chemicals you filter out of your synaptic gaps..

if you could imagine buckets with holes in them, being filled with dopamine and norepinephrine.. and draining, and filling.. thats kinda what should be happening, in a person not needing to take wellbutrin. but wellbutrin plugs up the holes, so to speak, and the bucket itself, would be whats actually absorbing the dopamine and norepinephrine - if that makes sense. .. so you're basically getting a dose of your brain goo that you're totally not accustomed to\r.. and its probably the dopamine that you're feeling.

are you feeling agitated, tense and short with people?

LaVieEnRose
06-11-11, 06:18 PM
Im taking 150 XRs (supposed to be twice a day but ive dropped my dose). Ive had this with wellbutrin. I mean.. it sounds largly like an adjustment period thing. It has only been day three.. and this is what welbutrin does.

in essense it makes you overload on Dopamine, and Norepinephrine. It does this by cutting off how much of those chemicals you filter out of your synaptic gaps..

if you could imagine buckets with holes in them, being filled with dopamine and norepinephrine.. and draining, and filling.. thats kinda what should be happening, in a person not needing to take wellbutrin. but wellbutrin plugs up the holes, so to speak, and the bucket itself, would be whats actually absorbing the dopamine and norepinephrine - if that makes sense. .. so you're basically getting a dose of your brain goo that you're totally not accustomed to\r.. and its probably the dopamine that you're feeling.

are you feeling agitated, tense and short with people?

:D Thanks for the radtastic explanation on the synapses/reuptake inhibition! How have I been with people? I've varied from just completely blank and just.. *crickets*.. sitting here... doing and thinking nothing, to completely freaking out, both with cave-man-esque vocabulary.


I'm taking it with Adderall IR.. which also could definitely point to a dopamine overload, but it seems like it totally obliterates it's effects.. and worse. It feels like the goo is there before I take it, but then plugs up the wrong side and the reuptake bucket effing sucks up all my goo!! It leaves me feeling more ADHD than I experience if I just went without stimulants entirely, and not only that, but later in the day I feel unusually sad and upset.. and I can't express it!


Le sigh. I know it's only been a short time (it's actually been a week, not 5 days like I posted), but I feel like it's so extreme that in any case, I need to reevaluate with my psychiatrist. Of course I came to this realization Friday at like 5:03pm, but he called back and said to go off until we meet next week again. Hence, the reason I'm able to write this.


I hesitate to post about med experiences here because my body is so sensitive. But this feedback is very valuable and I wasn't having an allergic reaction, so I may just have to push through it.

anonuser999
06-15-11, 04:10 PM
I've had two go-rounds with Wellbutrin. It does zap my short-term memory and make some areas of my brain pretty fuzzy, but the benefits it has on my mood, energy level and motivation make it worth it.

I've sort of come to terms with it by explaining it this way: Prior to being on Wellbutrin (and antidepressants altogether), I was extremely complicated. Probably way too complicated. I ruminated and obsessed and got moody and was inconsistent. I was extremely intelligent and observant and my critical thinking was pretty good, but I didn't ever use it for anything - My mood, attentional issues and depression held me back from using it for anything productive.

Wellbutrin (which I take in combination with Zoloft and Adderall) has simplified me. Am I as sharp as I used to be? No, not really. But I am less unhappy. Things are easier to accomplish, I don't beat myself up as much as the dopamine effects it has work well with Adderall's diminishing effects on those chemicals. I have to work a little bit harder to recall certain things and work through complicated multi-step processes, but all in all, I'm glad I'm on it.

LaVieEnRose
06-16-11, 12:33 AM
Well, I met with my psychiatrist this morning and he put me back on, with some changes in the dose of my Adderall IR. I took it again today and I just feel strange.. I feel my thoughts going away again.. and my speech has been fluent these past couple days off it, but now it's going back to stammering through what I'm trying to communicate. Likewise, I'm feeling more sad in the late afternoon/evening.

I'll give it a go. I have plans to go camping this weekend, but I guess I'll just bow out if it's as bad as it was last week. It's rough when you can't tell if the drug just isn't right for you or if it's the adjustment. Only one way to find out.

Hathor
06-16-11, 05:33 PM
I continue to have problems (day 24). The brain fog was diminishing but now seems to have stabilized at a level that leaves me acceptably stunned. Also I went to 300MG at day 14 and after a week on that I felt overloaded and not well at all. About 2 days ago I felt very faint and my head felt like it was caving in. I cant help but think I may be in the minority that could get a seizure from Welly, and I went down to 150MG yesterday. There were some positives starting around day 19, but most of them have not surfaced for about 2 days. One interesting positive I have recieved from this med is I have lost interest in pornography, and my fantasies have been romantic rather than purely sexual for the first time in years. I will miss that effect, but I took 150MG this morning and if the Welly doesnt do something drastic today I will not take another one

Hathor
06-16-11, 06:45 PM
well I tried to say unacceptably stunned but I guess I was too stunned to do it right. Tried to edit the post but cant see any edit button, does it not exist or am I too stunned to find it

so this post has an edit button but my post above it does not. wonder if it dissapears after a certain amount of time or if it is a glitch

sorry to go off topic

anonuser999
06-17-11, 03:31 PM
It took me about a month to get the "regular" effect from Wellbutrin. It was very up and down leading up to that, and it settled somewhere in the middle. I also feel pretty braindead at times - "Stunned" is a good word for it.

I will caution anyone going off this medication who has ADD or anxiety - When I quit it the first time, I went cold turkey, and that was the worst decision I've ever made in my entire life. I went nuts for a solid month. It was completely awful. I don't care what the internet or your shrink says, if you're going to go off of this stuff, take your time and back off slowly. It's not supposed to have a very acute discontinuation syndrome, but it just about did me in.

aarondev
07-19-11, 03:57 AM
Hey,

Few things:

Cold Turkey: Don't do it. This is my second try with WXL (generic) and the first time I was on it I went cold-turkey and went suicidal. It was so messed up. I mean, I had thoughts prior but never near-action!

Brain fog: THANKS so much for the posters on here. I thought there was something weird going on. When I first started I was having Strattera too and thought the two helped. I noted that Strattera was great at tuning out the thoughts in my head and limiting them MORE. But I stuck with it. Now, though, I'm off Stratt and its not good.

Things were so bad last week that I actually stopped taking WXL. I hadn't refilled the Script and went like 2.5days without it. Its ironic but now, similarly, I've not had a dose for like 24hrs since a weird scheduled day and in reality I'm getting stuff DONE. I'm not sure if I'll continue with it or not.

Impact on Depression: What it does for me is sort of makes me no longer 'feel'. What I mean is that I'm able to sort of just feel 'in the middle'. Nothing really makes me upset (which is good). And it helps with feeling more cheerful faster.

Overall, I dislike it now. I mean, I was originally on the brand but switched since it was really expensive. But now I'm considering going back. Just to make sure its the medicine or the generic as oppose to what's present. I think the biggest problem is that anything concentrated; anything real; anything that requires sustained mental thought I just DON'T want to do. The problem is LESS than without it. For example, making a phone call or getting out or dong the laundry was a huge task before whereas now, somewhat less). But still, reading these forums or writing emails.. NOT good