daisyo75
09-10-04, 11:03 AM
One of my recent areas of focus has been trying to figure out what, if any, medications I can take while I am breastfeeding. This is an area of concern for me and I wanted to share some of what I have found.
Let me start by saying that I am not claiming to be a medical professional and choosing to take medication while pregnant or breastfeeding is ultimately a decision that must be made by the mother along with her Doctors. My intent is to share my interpretation of the information that I have gathered. I will make an attempt to leave out my personal opinions on the subject and post them separately.
It is true that very little reseach has been done on the levels that many ADD drugs pass through to breast milk. However, there is at least one researcher that conducting studies and publishing data on this. Interestingly, he is currently looking for participants for a Ritalin study so hopefully there will be some published data on this in the near future.
Dr. Thomas Hale publishes a book called Medications and Mothers' Milk which is largely based on his own research. It is the only reference that I am aware of that specifically discusses the actual affect that different medications have on breast milk. This book is specifically targeted toward medical professionals and includes pharmacology information on several hundred different medications. In addition to prescription medications he covers over-the-counter meds, some herbal supplements and even some street drugs(obviously these are listed as Contradindicated).
This Dr also has a website http://neonatal.ama.ttuhsc.edu/lact/index.html There is additional information available here as well as a forum where medical professionals can request additional information on behalf of nursing mothers. Dr Hale generally holds the position that a drug that is needed in order for the mother to function at an appropriate level to care for her child(ren) (i.e. depression) is a situation where the benefit of continuing to breastfeed outweighs the risk to the childs exposure to the medications.
Now as far as ADD medications go the research is in the very early stages. Most of the data available on Stimulants is from mothers using street drugs. However, a few mothers have been studied with Ritalin and at least one with Adderall. The information available shows that the levels that pass through to the child would be quite low. Dr Hale suggests that any relative dosage less than 10% is probably within safe levels. The studies done on Ritalin and Adderall show no more than a 1.9% relative dosage passed to the infant. The relative infant dosage is calculated using a mathemetical equation which takes the weight of the child into consideration.
An excerpt from Dr. Hales book provides some points to consider:
Key Points About Breastfeeding and Medications
Avoid using medications where possible. Herbal drugs, high dose vitamins, unusual supplements, etc. are simply not necessary; recommend avoiding the risk.
If the Relative Infant Dose is less than 10%, most medications are quite safe to use. The RID of the vast majority of drugs is <1%.
Choose drugs for which we have published data rather than those recently introduced.
Evaluate the infant for risks. Be slightly more cautious with premature infants or neonates. Be less concerned about older infants.
Observe breastfeeding mothers for depression as the incidence is high.
Recommend antidepressants in depressed breastfeeding mothers. The risks of a depressed mother to the infants are simply too high.
Most drugs are quite safe in breastfeeding mothers while the risks of not breastfeeding and of using infant formulas are much higher for the infant.
Discontinuing breastfeeding for some hours/days may be required partiularly with radioactive compounds.
Choose drugs with short half-lives, high protien binding, low oral bioavailability, or high molecular weight.
Adapted from "Drug Therapy and Breastfeeding: From Theory to Clinical Practice"
Let me start by saying that I am not claiming to be a medical professional and choosing to take medication while pregnant or breastfeeding is ultimately a decision that must be made by the mother along with her Doctors. My intent is to share my interpretation of the information that I have gathered. I will make an attempt to leave out my personal opinions on the subject and post them separately.
It is true that very little reseach has been done on the levels that many ADD drugs pass through to breast milk. However, there is at least one researcher that conducting studies and publishing data on this. Interestingly, he is currently looking for participants for a Ritalin study so hopefully there will be some published data on this in the near future.
Dr. Thomas Hale publishes a book called Medications and Mothers' Milk which is largely based on his own research. It is the only reference that I am aware of that specifically discusses the actual affect that different medications have on breast milk. This book is specifically targeted toward medical professionals and includes pharmacology information on several hundred different medications. In addition to prescription medications he covers over-the-counter meds, some herbal supplements and even some street drugs(obviously these are listed as Contradindicated).
This Dr also has a website http://neonatal.ama.ttuhsc.edu/lact/index.html There is additional information available here as well as a forum where medical professionals can request additional information on behalf of nursing mothers. Dr Hale generally holds the position that a drug that is needed in order for the mother to function at an appropriate level to care for her child(ren) (i.e. depression) is a situation where the benefit of continuing to breastfeed outweighs the risk to the childs exposure to the medications.
Now as far as ADD medications go the research is in the very early stages. Most of the data available on Stimulants is from mothers using street drugs. However, a few mothers have been studied with Ritalin and at least one with Adderall. The information available shows that the levels that pass through to the child would be quite low. Dr Hale suggests that any relative dosage less than 10% is probably within safe levels. The studies done on Ritalin and Adderall show no more than a 1.9% relative dosage passed to the infant. The relative infant dosage is calculated using a mathemetical equation which takes the weight of the child into consideration.
An excerpt from Dr. Hales book provides some points to consider:
Key Points About Breastfeeding and Medications
Avoid using medications where possible. Herbal drugs, high dose vitamins, unusual supplements, etc. are simply not necessary; recommend avoiding the risk.
If the Relative Infant Dose is less than 10%, most medications are quite safe to use. The RID of the vast majority of drugs is <1%.
Choose drugs for which we have published data rather than those recently introduced.
Evaluate the infant for risks. Be slightly more cautious with premature infants or neonates. Be less concerned about older infants.
Observe breastfeeding mothers for depression as the incidence is high.
Recommend antidepressants in depressed breastfeeding mothers. The risks of a depressed mother to the infants are simply too high.
Most drugs are quite safe in breastfeeding mothers while the risks of not breastfeeding and of using infant formulas are much higher for the infant.
Discontinuing breastfeeding for some hours/days may be required partiularly with radioactive compounds.
Choose drugs with short half-lives, high protien binding, low oral bioavailability, or high molecular weight.
Adapted from "Drug Therapy and Breastfeeding: From Theory to Clinical Practice"