View Full Version : Drug Resistant ADHD


Rellwood74
05-17-12, 01:20 AM
So I am 38, diagnosed ADHD as well as bi-polar. The long and the short of it is that even though I have been prescribed Concerta, Strattera and adderall for the ADHD, I have had absolutly no changes. I feel like the main character in the movie Limitless, before he takes the brain enhansing drug. I just saw a new Dr. and he is trying me on Lamictal.

I am currently on 500 Depakote, as well as 300 Seroquel ER, and 20mg Adderall XR. My problematic symptoms include impulsivity, hyper focus, extream irritability, unable to bear to be in a line, I talk a mile a minute (really, honestly I speak so quickly I have difficulty usingna telephone because no one can understand me), forgetfulness, inabillity to maintain conversations, easily distracted, unable to keep my home clean, terrible procrastination, also if the smallest thing gets in my brain I will not rest until it's answered to the best of my ability.

For the last year was able to do ok in my classes, but I noticed when my previous physician decided to stop my seroquel (after being on it for years) at once and introduce Depakote (I very quickly was put back on the Seroquel after I went into a really bad manic episode within days of stopping the Seroquel). Now the Depakote is still being prescribed, but I noticed that the focus and concentration I had a tiny bit of last semester is completly gone this semester. Just a FYI. So this semester (Spring) on the Depakote, Concerta, Seroquel combo - the ADHD got so bad I had to drop 3 classes (I NEVER drop classes). Last year I tool Math, Sociology, Psychology, and Phillosopy and got 3 -A's and a B. I need to get a handle on the ADHD.

People who have positive results to their ADHD meds report amazing changes. Their lives take such positive turns for the better.

I would simply like to be able to keep up my school courseload and not be ashamed if anyone "pops over" unnanouncede to my apt. So, any suggestions? My bipolar hasn't been diagnosed as 1 or 2 so I don't know. I do know that I have had multiple hospitalizations and suicide attempts as well as some other unconventional symptoms however, no big gradiouse, happy, creativity. For the most part my bipolar is stable. Also, I am sober for 3 years. :)This was my first post, so be kind.

My Psychiatrist actually advised me to bone up on meds and get help so that I am an "expert" in it as well. So, if I am given some suggestions, he would be willing to consider them.

Morning - Adderal 20 mg ER (New scrip)
Night - Depakote 500 Seroquel 300 (Depakote last 6 mos, Seroquel 3 yrs)
Twice daily - Lamictal 25 mg tabs (started 5/12/12)

sarahsweets
05-17-12, 04:35 AM
How long have you taken the adhd meds? Have you tried different doses? Sometimes it takes awhile to find the right dose.

Driver
05-17-12, 04:40 AM
Your dosage of Adderall is a tad low, and because you're taking other meds there's also the possibility that they're interfering with each other and you may need to take even more for effect - your doc should know about this.

Retromancer
05-17-12, 05:16 AM
Emphatically a case of "your mileage may differ". The best rule of thumb I have read is that at best medication can relieve 40% of your symptoms -- and you do not get to choose which ones get to be relieved.

People who have positive results to their ADHD meds report amazing changes. Their lives take such positive turns for the better.

Abi
05-17-12, 05:56 AM
I don't know about the 40% thing. Maybe for ADHD, but not other conditions.

My bipolar/depression and anxiety meds relieve between 70 and 100 per cent of my symptoms.

Rellwood74
05-17-12, 12:53 PM
I am currently just starting on the Adderal, so my Dr. is taking it slow. He has already mentioned that if I handle the Lamictal well, we will probably increase both. I am having about 90% control over the bi-polar issues with the seroquel, but the weight increase has him trying the Lamictal as a possible replacement. He won't take me off the Seroquel until he is sure. I know that I am only expected to see some change in the ADHD symptoms, but I tell you I would take ANY positive change over the life time of struggle to just do the things that seem to come naturally to everyone else.

Rellwood74
05-17-12, 01:03 PM
I was started on Stratera in 04 but quickly taken off due to side effects.
From 05-09 I was on Concerta/and or Ritalin - My doseage went up to two 36(?) extended relsease tabs a day. They really didn't seem to do anything, my doctor would ask, "How's your focus and concentration?" I kind of would shrug my shoulders because I didn't feel any different than I had my entire life. That is the hardest part--describing how I feel. I can't describe what my lack of focus feels like any more than a blind person can say what a lack of sight feels like. However, I suspect that if that blind person were able to start making out shapes and colors he would be able to report on that. SO the Concerta really didn't work. I lost insurance for a few years until Jan 2011 then was represcribed Concerta with the same (no)results. I finally got in touch with a Doctor this week who is willing to really tweak with my meds. My last Doctor decided if Concerta and the Adderal weren't working we should just throw in the towel and I would have to start learning how to manage my ADHD better w/o meds, So that is where I stand.

James is weird
08-29-12, 01:39 AM
before i start: Dont take anything im saying as doctorine, consult a doc b4 changing any meds/dosages yada yada - what im writing is just for a fresh perspective etc




I HATED depakorate!
Was The worst thing ive ever put in my body,
The side effects were a nightmare!
I felt stupid, couldnt remember chunks of my day, felt like i was falling out of mental conciousness!

I am on Lactimal now - Havent experienced a single side effect to date xD
The pill even taste nice xD

I would agree with the others in saying maybe, up your dose.
or switch to dexedrine - Wonder drug ^_^

Your on an extended release, maybe ask for a Instant Release, its easier to find your happy medium as you can try more than one option a day.

You may have become tollerant to your adderall dose without noticing,
It took me a while to see that in myself.

And ive noticed you double up on meds
I was under the impression that sodium vaporate (depakorate) and seroquel are both sodium channel blockers - and hence do the same thing?

If your just using seroquel cause its easier to sleep on it.... I wouldnt.
If my minds racing i find a regular dose of dexedrine 45 mins b4 sleep works a charm (even though i think it may affect the quality of my sleep - REM related )

I would deffinatly see a more specialised Pdoc!
Especially if your psychiatrist recomended it!

Hope the thoughs stop racing! :)

awdcivic
03-24-13, 10:02 PM
Adderall didnt work for me vyvanse even at a lower comparable does does. Cocain did not do anything to me the one time I tried it and its supposed to be like ritalin. Try a different medicine I say.

FocusPocus10
05-15-13, 08:53 PM
Morning - Adderal 20 mg ER (New scrip)
Night - Depakote 500 Seroquel 300 (Depakote last 6 mos, Seroquel 3 yrs)
Twice daily - Lamictal 25 mg tabs (started 5/12/12)

Mood stabilizers block dopamine so they resist your adderall. Drop it like its hot! No but really, you can't cure psychotic symptoms and ADD, unless you invent a new drug. Maybe try high dosage provigil instead and/or with your adderall, other than that let me know if you figure it out.

sarahsweets
05-16-13, 04:35 AM
I have been on a mood stabilzer for 9 years and never had an issue with stimulants working.


Mood stabilizers block dopamine so they resist your adderall. Drop it like its hot! No but really, you can't cure psychotic symptoms and ADD, unless you invent a new drug. Maybe try high dosage provigil instead and/or with your adderall, other than that let me know if you figure it out.

BellaVita
05-16-13, 04:43 AM
I also take Lamictal, and from what I've experienced it does not noticeably reduce Adderall's effectiveness.

Darksanity
05-17-13, 02:06 AM
One needs to understand that medications only mask some of the symptoms. But definitely not 'cure' ADHD. CBT may help with behavioural issues. But even then if you have crap executive functions since birth then unless you got a team that works for you everyday including a secretary, life coach, talk-therapist, etc. then I don't think you can get to your 'full potential'.

I might just be pessimistic because I feel the same. I think there might be hope with DBS (http://en.wikipedia.org/wiki/Deep_brain_stimulation).

DmxDex
06-11-13, 07:26 AM
One needs to understand that medications only mask some of the symptoms. But definitely not 'cure' ADHD. CBT may help with behavioural issues. But even then if you have crap executive functions since birth then unless you got a team that works for you everyday including a secretary, life coach, talk-therapist, etc. then I don't think you can get to your 'full potential'.

I might just be pessimistic because I feel the same. I think there might be hope with DBS (http://en.wikipedia.org/wiki/Deep_brain_stimulation).

Things like this people do not want to hear. Way to negative.

Everyone with ADHD has the ability to go somewhere.

Its easy to be negative, i am.

But the though of feeling better and being able to actually do normal things in life spurs me on.

known_guy
06-12-13, 01:49 PM
When it comes to procrastination especially, regular therapy sessions help. Whether it be CBT or what-have-you; even talk therapy! It might even just help by holding me little more accountable, in a sense. Medications only do so much. People may not like to hear certain things, I know, but sometimes these things are just truth and/or good to remind oneself of, I think. Other than procrastination, I believe I worked on my forgetfulness over the years on my own. I have heard people say medication gets you 50% of the way there (I think the context being depression, but I think it applies to ADHD too), but I prefer to think the medications get me 25% of the way there. As for my daydreaming, while it is totally a hindrance and in certain situations detrimental, I really appreciate that aspect, that part of me. I like to say that I'm never truly bored, for I always have my tangential thoughts/thinking and daydreams to keep me company.

dresser
06-19-13, 01:31 AM
maybe I cannot reach my full potential, my dream ideal, and that can get me depressed, down, grumpy, etc because I'm always looking waaaaay out in front of me.
and it's sooo far away. I feel much better when I look to/or see that I have moved just one infintissimal
fraction AWAY from where I was, and that distance is easyer for me to see, and more in my feasible present N possible doing.
N just now I realize I can appreciate ME for tryin . the appreciate me part is new for me yet its good for my sence of worth, other part I learned the hard way and a lot of heart ache ago. pluss learning is a two way street and thank yoozz this is the first time I have gotten to see what has been rummaging around in mind it was always unclear. thank you again stay wel all

arrstddvlpmnt
07-06-13, 02:45 AM
I really don't know much about bipolar, but if your talking a mile a minute isn't a symptom of your bi-polar, it sounds like it could be an effect of the adderall. Something else may be causing your inattention and lack of focus, because most people respond really well to stims at least at first. The fact that you didn't respond to most of them tells me that the adderall may not be helping. If the problem is a magnesium deficiency, it would actually make things worse.

Have you had blood work done? Are you deficient in any minerals? These kinds of deficiencies can often hold clues as to whats actually going on.

I'm not a medical professional, so I don't condone making changes in your medications without consulting your doctor. I would still encourage you to learn and research as much as you can about potential causes of ADHD. There's a tendency for people to paint a broad brush and say it's dopamine or NE, and that isn't always the case.

Modafinilguy
09-29-13, 06:02 PM
I am very skeptical about taking anti-psychotic medications for bipolar and stimulant medications for ADHD.

Stimulants can trigger manic episodes and psychosis in people with bipolar.

It seems like a bad idea to take it if you have bipolar. If I did, I would not take stimulants.

Likely you are not feeling much from the stimulant because you are on multiple meds that would reduce its effect, especially the sequel.

I have seen people who have injected large amounts of crystal meth take 200mg seroquel and be knocked out within half hour and sleep for 24.

Even if you do have both bipolar and ADHD, treating your ADHD with stimulants poses a risk to your bipolar.

If I was in your position I'd seek another psychiatric opinion.

BellaVita
09-29-13, 06:40 PM
I am very skeptical about taking anti-psychotic medications for bipolar and stimulant medications for ADHD.

Stimulants can trigger manic episodes and psychosis in people with bipolar.

It seems like a bad idea to take it if you have bipolar. If I did, I would not take stimulants.

Likely you are not feeling much from the stimulant because you are on multiple meds that would reduce its effect, especially the sequel.

I have seen people who have injected large amounts of crystal meth take 200mg seroquel and be knocked out within half hour and sleep for 24.

Even if you do have both bipolar and ADHD, treating your ADHD with stimulants poses a risk to your bipolar.

If I was in your position I'd seek another psychiatric opinion.

That is true. Although I'm sure untreated ADHD poses a significant risk too...