For the past 3 mos I've been having problems with Adderall, It has not been that effective for me like it used to be. I don't feel any effects at all. At first I thought that it was tolerance, so I stopped taking Adderall for 2 whole weeks and still the drug was doing the same thing. So yesterday I went to the Shire website and boy was I surprised! It turns out Adderall is made so much different than Dexedrine or Desoxyn. For example I've been taking the 15mg immediate release tablets and did any of you know that you're not really getting the full 15mg! You're only getting a total Amphetamine base equlvalence of only 9.4mg! I couldn't believe it myself! Thats because Adderall uses different Amphetamines at lower doeses! If anyone for example is taking 5mg you're getting 3.13 mg equlvalence:7.5mg 4.7mg equlvalence;10mg 6.3 mg equlvalence 20mg 12.6mg equlvalence 30mg 18.8mg equlvalence and so on. If any of don't beleive me then go to the shire website or adderallxr.com and see for yourself. I had Adderall e-mail me the Prescribing information on the immediate release because only the AdderallXR was available but there both the same thing. I then checked out the Glaxo Smith Kline website who makes Dexedrine and when you take Dexedrine you're getting the full Dextroamamphetamine mgs wheather its immediate release or the sustained release capsules. I also checked out the Ovation Pharma webite who makes Desoxyn & it was the same thing. It does seem that Desoxyn is used more for Obesity than ADD. I see my Dr. on Tuesday and I'm deffinately switching!

It's no secret that Adderall dosage is different from Dexedrine dosage - you take more Adderall, on a mg for mg basis than you would dexedrine - this is because the various amphetamine salts are not equivalent in strenghth to dextroamphetamine. You sound as if you feel cheated by this information? More is not better when it comes to stimulants - you take whatever you need to treat your symptoms - more than that and your symptoms get worse. It doesn't matter that you take 15mg of Adderall or 10mg of Dexedrine or 20mg of Ritalin - one drug is not necessarily better or stronger or more effective than another, it's whatever works. So if Adderall isn't working for you, you should talk to your doctor about that. I'd be carefull in "demanding" a change in medication from your doctor - doctors can get a bit testy when patients demand things, having spent all that time and money on med school - especially if you're thinking of asking for Desoxyn.

You made a good point. I'm not going to demand that I switch to Desoxyn. I downloaded & read about Desoxyn from the Ovation Pharmaceuticals website and I must say that after reading about the drug it does has some serious side-effects, such as tolerance to the anorectic effect that develops within a few weeks. And when this happens the drug should de discontinued. Anorectic are drugs that are used in obesity. When patients take this drug for that purpose they can only take this drug for only a few weeks. Desoxyn also has active metabolities so the drug is heavly absorbed into the system which is why it has such a high chance for dependance & abuse. I can understand why so many Doctors are hesitant about prescribing this drug, in fact my Doctor told me that he has only prescribed this drug only a few times, and on top of that he has to show documentation every time he does more so than the other Stimulants. I will ask my Dr. about Dexedrine because I've tried almost all the others (Ritalin, Adderall, Straterra etc.) I've been taking Adderall again for 3 mos. I took Adderall before about a year ago through the same Dr. so I don't think that he won't suspect that I'm trying to abuse the drug. Since I still have Adderall in my body I will also wait 3 weeks before I take my first dosage to be on the safe side. I read that to properly get the drug out of your body you have to stop taking Amphetaimines for about 3 weeks if you use it often because it takes this long for the brain to return to the state it was in without Adderall especially if you're a chronic user or if you build up a tolerance. I don't consider myself a chronic user but I want to start off taking the new drug without any of the former Adderall in my body. Again thanks for writing me back.

Desoxyn isn't an evil drug, it's just that the stigma attached to methamphetamine makes it a real hassle for a doctor to prescribe and they are going to be on the lookout for people asking for it specifically. In theraputic use, it won't be that much different from Dexedrine or Adderall. It's also really really expensive and hard to find - very few pharmacies are going to carry Desoxyn and the pharmacist will undoubtably be very careful in dispensing it. That said, it's not worth the hassle unless all else fails to releive your symptoms.

a5alive, thanx for the info. But watch, because i made a jump from adderall, 60mg 2x daily to dexedrine. I thought i had gold in my hand when i got the script, up on how some other users on another forum talked about it.

Well, My doc persribed me two 15mg of spanuals, daily. I was elated. Well, i got the script, and took it. Took another after the proper time. NOTHING. I ended up trying 2! NOTHING, very little, But then If i can remember it was the generic dexedrine, made by that one company, which i cant remember, but i believe greg knows. I figured because of my insurance, i better not try the regular release, maybe spanuals were not my think, so my doctor put me back on adderall and added 30mg, so it worked out great.
When i was informed that when you take XR versions, say 15mg, really its releasing 7.5mg for the first 4hrs. SO , thats a big drop from 30mg of adderall IR, to 7.5mg (actually15mg) of dex, plus the generic brand from this company had alot of complaints. I probably could have taken 4 spanuals. But i didnt want to do such a think, so my doc, switched me back, luckily he didnt mention Ritalin, cause i just dont like it. Reminds me of a rollicoster ride, up and crash and down. Dysoxin, well, i never heard anyone taking it,but i imagine as greg said, meth addicts, i know , 2 of them already died. So, i can imagine, addiction , especially if one is an addict. My doc knows i abused oxys, but i guess, due to the fact he has knowledgeof drug addicts having add, and i did not ever abuse speed or cocaine, so he wrote me amphetamines. To this day, 8 months or so, i still am taking what i took 5 months ago, but sometimes, i may take a 4th dose, if im up late and dont have to get up the next day. I dont believe thats abuse, but if someone is taking, say 60-90mg at once when there perscribed 30mg, then there headed for a problem, like a friend of mine. He will never get his tolerance back down, he says to me, ok im stopping this abuse, well he ran out, and hes freaking out. Calling me, for halfs and stuff, but i said you need a break , for your own good.
IF you get perscribed 60 pills a month, and eat them all in 10 days, your very much introuble. But he never told his doc about his cocaine addiction, and now he abusing them, and hes complaining hes not high or feeling them. Well, its making me mad, because, hes gonna end up on meth probably , once someone gets it for him or something like so. I even was helpful and held 20 of his meds to try to help him , and he still, was at my door 2x a day, so it didnt make sence, and I cant say no, there HIS. ADDICTs, and im not better, but while there in there addiction, lie lie to anyone. I can tell a friend, when a friend doesnt come to your apt, only when hes "feeling good" or try to get your meds, but whenyou invite them over when i know he doesnt have any, its no or try to get me this or that. Now i see how it is, and its sickening, esp with dope, but he swears he has add, and "takes a bit too much and will stop abusing them. Well see. But if you think about if, id rather see him eat a few adderall than snort the white powder or H.

Why did they even make Meth in a pharmacutical form. When Meth is schedule 1, well i guess its like sorta, heroin and oxycontin. Heroin is schedule 1 and oxy is 2. Basically there the same, although in ways are different. I dont understand the FDA, or the gov. THey have almost for every schedule 1 drug, they have an "alternative" which is or can be perscribed. Besides extacy and acid, the rest are very close.

I think dad said they didn't even have it here (in Iowa, the Meth capital of...the midwest? The central time zone? I don't know, but it's crazy) ; he doesn't think people can actually get prescribed meth (Desoxyn)--or maybe, rather, he doesn't think you'll be able to get it, 'cause like he said, no one--and definitiely if there's a place they won't it's here--will carry it in their pharmacy. He's (dad) scared as hell about my dex as it is. Thinkin' people are going to break into the house and kill me to get to a few BARR manufactured generic spansules which I was told from the beginning suck and am truly starting to believe that they must. :rolleyes:

Sorry for interrupting a conversation--just thought I'd mention the Iowa thing--mind you, dad's not a shrink, though, just a GP.

Man, the Mallinkrodt pharmaceuticals version of those generics better be an improvement--I don't think the BARR pharm stuff is working like it should, dude. It was a bit better for a while, but now it seems to have just stopped. Strangely. I look like I'm in the late stages of cancer, with circles under my eyes and all. Yuck.

Hey, good luck, y'all. Gonna try to go to sleep. The lines of words on the screen look like they're going somewhat diagonally down from left to right...don't think that's a good sign. Night.

Chrys


Desoxyn isn't an evil drug, it's just that the stigma attached to methamphetamine makes it a real hassle for a doctor to prescribe and they are going to be on the lookout for people asking for it specifically. In theraputic use, it won't be that much different from Dexedrine or Adderall. It's also really really expensive and hard to find - very few pharmacies are going to carry Desoxyn and the pharmacist will undoubtably be very careful in dispensing it. That said, it's not worth the hassle unless all else fails to releive your symptoms.

I just switched from ritalin 40 mgs per day short acting tablets to 40 mgs dexedrine tablets (10 mgs 4 times a day) and I really like dexedrine. No side effects really. I do have to say that I am not as fully focussed as I would like to be and would like to get trial bottle of desoxyn to see if that will work for me as needed. I am approaching finals right now. What do you think about that?

You could also consider a mono-amine oxidase inhibitor, B-selective, such as selegiline, at dosage between 1-10mg/day.

I've also had trouble with adderall working the same after a few days of taking it. I asked my Dr. about switching to Dexedrine and he said it would work the same as the adderall. Is that true? Has anyone had better luck with dexedrine than with adderall?

Dexedrine is very similar - the same drug composes 25% of Adderall, and the other 75% are not too different either - they metabolize at different rates, which makes Adderall "smoother" - in theory (I've never tried it so can't say first hand - I take Dexedrine). What was the problem with the Adderall after a few days? It's something I've heard alot - the drug seems to get less effective after the first week or two and people need a little more. After that, the dosage seems to "stabalize". My guess is that the body adjusts to the "novelty" of Adderall after the first week or two or perhaps the improvements just seems more profound at first and as people get used to the med they realize they need a bit more??? This doesn't seem to be tolerance in the usual sense of the word.
Has Adderall stopped working all together? How much are you taking? It could be that you need a bit more - it often takes a little while for people to find the right dose. Are you taking "regular release" Adderall or Adderall XR?
It's my feeling that it's easier to figure out the dosages when you use immediate release formulations - there's less doubt about when the second dose is released and how effective it is - the second dose with XR releases slowly.

good luck getting desoxyn buddy...