View Full Version : Can DNA "work" without Uracil?


mildadhd
03-18-13, 03:14 PM
(A question from a different thread.)

Insight appreciated?


Can DNA "work" without Uracil?


DNA = ADENINE, GUANINE, CYTOSINE, THYMINE

RNA = ADENINE, GUANINE, CYTOSINE, URACIL


What is the relationship between, Thymine and Uracil?

(what are both, the similarities and the differences, between Uracil and Thymine?)







i!i

mildadhd
03-18-13, 03:23 PM
Side Note: ( I messed up the Poll options)

I meant to make "sometimes" and "other",

two different options.

But can't edit the poll.


Can DNA "work" without Uracil?

Yes

No

Sometimes

Other


I picked "other"because to the best of my knowledge..


DNA needs RNA to "work"

and RNA needs DNA to "work"?



(I am not claiming to know for sure, but would like to know more?)

Trooper Keith
03-18-13, 04:26 PM
This question doesn't make sense and indicates that you're not really familiar enough with DNA and RNA to be able to have a meaningful discussion about it. Do some research on what DNA is, what RNA is, and don't worry too much about the actual chemicals as much as what they are.

mildadhd
03-18-13, 04:33 PM
This question doesn't make sense and indicates that you're not really familiar enough with DNA and RNA to be able to have a meaningful discussion about it. Do some research on what DNA is, what RNA is, and don't worry too much about the actual chemicals as much as what they are.

I have lots of information in front of me.

Both books and links.

I have been researching the topics.

(and thinking about the topics for a while now)

Your unwillingness to answer the question,

only makes me more curious.

Interesting.



I am assuming since you didn't answer, you don't know the answer?

Because the question doesn't make sense to you doesn't make it bad question.

To me, it is a good question.

Wouldn't you like to know?

.

Lunacie
03-18-13, 06:53 PM
DNA doesn't have uracil, so therefore it seems to work without it, no?


What DNA does: long-term storage and transmission of genetic information

What RNA does: transfers the genetic code needed for the creation of
proteins from the nucleus to the ribosome.

DNA is a double-strand molecule, RNA is a single strand. They do different
jobs, so they have different molecular makeup.

mildadhd
03-18-13, 07:14 PM
DNA doesn't have uracil, so therefore it seems to work without it, no?


What DNA does: long-term storage and transmission of genetic information

What RNA does: transfers the genetic code needed for the creation of
proteins from the nucleus to the ribosome.

DNA is a double-strand molecule, RNA is a single strand. They do different
jobs, so they have different molecular makeup.


Lunacie,

Thanks for your interest in the discussion.

From what I understand,

RNA has Uracil.

DNA has Thymine.


Uracil and Thymine are similar molecules. (if I understand correctly)


DNA = ADENINE, GUANINE, CYTOSINE, THYMINE

RNA = ADENINE, GUANINE, CYTOSINE, URACIL


DNA doesn't leave the nucleus,

RNA does leave the nucleus.

(I think)


So I am curious to know the difference/similarities between THYMINE and URACIL?

.

Lunacie
03-18-13, 07:25 PM
Lunacie,

Thanks for your interest in the discussion.

From what I understand,

RNA has Uracil.

DNA has Thymine.


Uracil and Thymine are similar molecules. (if I understand correctly)


DNA = ADENINE, GUANINE, CYTOSINE, THYMINE

RNA = ADENINE, GUANINE, CYTOSINE, URACIL


DNA doesn't leave the nucleus,

RNA does leave the nucleus.

(I think)


So I am curious to know the difference/similarities between THYMINE and URACIL?

.

It looks like DNA is protected from changes within the body.

The RNA is supposed to change in order to create different things.

The cells change the uracil in RNA to thymine in DNA which is protected
by methylating it, so it doesn't change.

I'm not clear on what methylating is or how it happens.

mildadhd
03-18-13, 07:39 PM
It looks like DNA is protected from changes within the body.

The RNA is supposed to change in order to create different things.

The cells change the uracil in RNA to thymine in DNA which is protected
by methylating it, so it doesn't change.

I'm not clear on what methylating is or how it happens.

After the RNA leaves the nucleus,

( and does its thing)

does the RNA return to the nucleus?

mildadhd
03-18-13, 07:45 PM
What came first,

the Nucleolus or the Nucleus ?


Nucleolus

The nucleolus (plural nucleoli) is a non-membrane bound structure and is the centre of the cell.

[1] It is composed of proteins and nucleic acids found within the nucleus of eukaryotic cells.

Its function is to transcribe ribosomal RNA (rRNA) and assemble it within the cell.


The nucleolus ultrastructure can be visualized through an electron microscope,

while the organization and dynamics can be studied through fluorescent protein tagging and fluorescent recovery after photobleaching (FRAP).

Antibodies against the PAF49 protein can also be used as a marker for the nucleolus in immunofluorescence experiments.

[2] Malfunction of nucleoli can be the cause for several human diseases. It takes up to about 25% of the nuclear volume.


http://en.wikipedia.org/wiki/Nucleolus

Abi
03-18-13, 08:05 PM
URacil is a fundamental component of RNA

RNA is a fundamental building block of all life.

So no, nothing can 'work' without Uracil

Hope this helps

mildadhd
03-18-13, 08:46 PM
URacil is a fundamental component of RNA

RNA is a fundamental building block of all life.

So no, nothing can 'work' without Uracil

Hope this helps


I agree,

but I choose "other" in the poll because,

DNA can't work without RNA,

and RNA can't work without DNA.

(As far as I know?)(Not sure?)



What do you think came first, Nucleolus or Nucleus?

What do you think came first, rRNA or DNA ?


So far I understand that rRNA comes from the center of the cell,

called the Nucleolus?


DNA comes from the layer outside the center Nucleolus,

called the Nucleus.


There is no DNA in the Nucleolus, (center)

There is rRNA in the Nucleolus, (center)


But there is DNA in the Nucleus.


Any idea how DNA could come before rRNA?


Assuming the Nucleolus (in the center of the cell),

comes before the Nucleus?

( Interestingly RNA also has the ability to leave the Nucleus?)


Does Uracil come from the Nucleolus?

.

Abi
03-18-13, 09:06 PM
Retroviruses like HIV are comprised of RNA only.

Though viruses and prions are technically not considered "alive"

Asking whether DNA or RNA came first is a chicken-egg question. Same with nucleus / nucleosis.

I have no idea where Uracil is manufactured. Google is your friend.

mildadhd
03-18-13, 09:19 PM
Retroviruses like HIV are comprised of RNA only.

Though viruses and prions are technically not considered "alive"

Asking whether DNA or RNA came first is a chicken-egg question. Same with nucleus / nucleosis.

I have no idea where Uracil is manufactured. Google is your friend.


I can live with the chicken and egg theory for now.

That is pretty close to "both,

as we can get in such a short conversation.

I appreciate your and Lunacie's input.


If we considered brain development,

there is a specific hierarchy/order to brain development,

that is predictable.


Like the idea that the lower layer of dirt,

in the grand canyon,

came before the highers layers.


With this idea in mind,

I am assuming the center of the cell comes before the outside layers?

(Not sure yet)

Kind of wondering if any one knows?


!i!

Abi
03-18-13, 09:23 PM
There you go:

http://www.cellsalive.com/mitosis.htm

Hope this helps :)

Edit: This one is better: http://www.biology.arizona.edu/cell_bio/tutorials/cell_cycle/cells3.html

mildadhd
03-18-13, 09:42 PM
There you go:

http://www.cellsalive.com/mitosis.htm

Hope this helps :)

Edit: This one is better: http://www.biology.arizona.edu/cell_bio/tutorials/cell_cycle/cells3.html


I don't really understand the links yet. Interesting

Questions..

What are the differences between the Nucleus and Nucleolus,

rRNA, and DNA.

or Uracil and Thymine?

Abi
03-18-13, 09:46 PM
I don't understand what you mean by "differences"

The nucleosis is an ara of the nucleus where the DNA sits.

You asked about cell development and the links will give you the info you need.

saturday
03-18-13, 09:49 PM
not sure about your question. But biology is kinda cool isnt it.

mitosis and meiosis, how chromosoms duplicate, RNA codons and what they create, mutations...

all very interesting. :)

mildadhd
03-18-13, 09:54 PM
I don't understand what you mean by "differences"

The nucleosis is an ara of the nucleus where the DNA sits.

You asked about cell development and the links will give you the info you need.


According to this link below, there is no DNA in the Nucleolus. (center of the the cell),



Question:

Is DNA in the nucleolus?

Answer:

No. Nucleolus is a separate structure inside the nucleus. DNA is also housed in the nucleus, but not within the nucleolus.

http://wiki.answers.com/Q/Is_DNA_in_the_nucleolus

Abi
03-18-13, 10:00 PM
My bad.

rRNA transcription happens there; just checked. :o

mildadhd
03-18-13, 10:00 PM
not sure about your question. But biology is kinda cool isnt it.

mitosis and meiosis, how chromosoms duplicate, RNA codons and what they create, mutations...

all very interesting. :)


I was just going to go and try and figure out what are RNA codons. :)

Thanks for the list.

mildadhd
03-18-13, 10:05 PM
My bad.

rRNA transcription happens there; just checked. :o


No worries, I appreciate the conversation.

Do you see my question?

There is no DNA in the center of the cell.

There is rRNA in the center of the cell.


RNA is also very important like DNA, it seems.


I really like the links you posted,

but I need to take some time to understand the better.


Any insight is appreciated.

I learned a lot today.


i!i