View Full Version : Dex & SSRIs/SNRIs


getonline33
02-04-05, 11:29 AM
Hello. Does anyone have any experience in taking Dex along with multi selective reuptake inhibitor antidepressants? I took Adderal in the summer (30mg, 3x/day) when I was taking Welbutrin. I was able to focus great. At work, I could start writing a report and stay intently focused on it for hours. At home, I would mow the lawn, then not stop until it was perfect.

However, I took a break from the meds for about 3 months. Now, I'm taking 60 mgs of Cymbalta (similar to Effexor - hits serotonin & neopenephrine), and 60mgs of dex (30/20/10) per day (after reading other posts, I should add that these are barr 10mg generics). However, I feel very few mental effects of the dex. The physical effects are certainly there (increased heartbeat/dry mouth).

I'm surprised because from what I've read on these boards, 60mgs per day is no insignificant amount. Could the differences on how each (adderal/dex) work on my body be that great? Or is it more likely that the Cymbalta's effects are somehow blocking the full therapeutic effect of the dex? Should I give moving back to Adderall a try as a more valid test to compare against my original - and successful - 'control' situation?

Any thoughts are welcome.

Also, I've seen another mention of someone using Trazodone to help in sleeping when dex induced insomnia hits. Is this typical? Traz is a mood stablizer, boosting serotonin (the side effect happens to be extreme drowsiness). Why not prescribe a GABA active drug like a benzo or Ambien? The Traz left me groggy in the morning and with a headache. No more of that (interesting side effect fact - 1 in 6000 men will experience priapism; an erection that doesn't go away and may require surgery...first thing I did when I woke up after taking it was to look under the sheets...I was ok.) :)

Eric
Seattle

Gregster
02-04-05, 12:48 PM
Wellbutrin is stimulant like, so perhaps it in combination with the Adderall worked better than the Dexedrine and Cymbalta because of the additive stimulant effect? I haven't tried cymbalta but I take an SNRI called Remeron and find it works great with the Dex I take. It induces sleep quite well too, so it helps me with my insomnia.

KnittingJunkie
02-05-05, 04:27 AM
Insomnia? What's that? Good God, I need sleep. Maybe it's time to take some Xanax.