View Full Version : A good anxiety ssri that DOES NOT make you tired?


Newgirl804
07-24-13, 05:34 PM
I have tried Lexapro and Prozac, both are effective at reducing anxiety(not social anxiety though) however both makes me soooo tired. I am trying to get my ADD meds figured out too, and it's frustrating even the stimulants don't counter act my sleepiness. Any suggestions??

Parterxred
07-24-13, 05:57 PM
I'm not a clinician, but Celexa might be an option.

Abi
07-24-13, 06:01 PM
Generally the newer SSRI's have the lower probability of side effects / less severe side effects.

Maybe Viibryd? I know nothing about it apart from that it's the newest SSRI on the market.

karbouris
07-25-13, 04:54 PM
if you can handle it catapress is used offl label for anxiety. its not an ssri but has simi-lar qualties.

Newgirl804
07-25-13, 05:11 PM
So I am not even sure what cataplan is... My biggest issue is social anxiety. So I looled into meds specifically for that and all seem to have sedation as a big side effect:(

BellaVita
07-25-13, 05:16 PM
Aww...was gonna say Lexapro. Any chance you were on too high a dose?

Lexapro makes me hyper.

425runner
07-25-13, 11:34 PM
I have yet to find one. Lexapro at 2.5 mg seemed OK but the headaches from it were unbearable. It seems each of the SSRI has its own side effect; the latest one I tried was Prozac and while I loved the feelings of content it made me super lazy, I just didn't care about anything...all I wanted to do was lay around all day and do nothing....stoned all the time, stims wouldn't even touch it. I'd drink tons of coffee just to keep my eyes open.

Newgirl804
07-26-13, 07:15 AM
I am currently on Prozac, and I like the content feeling as well. I never got that off Lexapro just didn't really work, at first it was kinda sorta working then I was upped in dose and I wanted to sleep all the time! Even when I tried taking it at night.
Prozac was helping me sleep a bit better at 20mg and then when I started back on stimulants we upped it to 40mg. I am trying today to take one in the am and one later, we will see how this works.
I had to go up on the SSRI because stimulants will increase my social anxiety. I work in sales(oddly enough for such a socially anxious person). I went to the Dr yesterday and asked him what to do. He said to just give it a bit longer and see if that side effect goes away. Also I don't think he wanted to change it since we had to change my ADHD meds. I was taking vyvance and it was shredding my stomach up. So today I am trying concerta with a Ritalin booster.
I went from someone who couldn't stay asleep once her dog woke her up at 6am to someone who can take a nap whenever. That part is cool. However yawning all day at work stinks....

425runner
07-26-13, 07:36 PM
I know...never got that content feeling off of Lexapro either. How many mg of Prozac are you taking now? I found anything above 5 mg just knocked me out...but I'm not very anxious to begin with, just always behind on everything and have a very stressful job - dealing with clients etc. but the Prozac did help make me more sociable. Have you tried Zoloft?

Too bad it made me sleep all day...I could literally sleep away my life while on it. Gave it over a month to work too....

Fortune
07-26-13, 07:58 PM
I don't know that it works for everyone, but a low dose of zoloft has done wonders for my anxiety.

ana futura
07-26-13, 08:01 PM
Maybe serotonin is not the reason you are anxious? Excess serotonin will make anyone tired.

425runner
07-26-13, 08:02 PM
What do you consider a low dose? How long did it take you to get used to Zoloft? My main problem is depression/apprehension, will it help? Does it make you feel more cheerful or happy?


I don't know that it works for everyone, but a low dose of zoloft has done wonders for my anxiety.

ana futura
07-26-13, 08:03 PM
This is an interesting read- http://www.independent.co.uk/news/science/my-brains-tired-scientists-looking-at-seratonin-find-you-may-well-be-right-8519939.html

Researchers led by Professor Jean-Francois Perrier of the University of Copenhagen found that while serotonin helps to keep people going during the early stage of vigorous exercise, a build-up of the neurotransmitter in the brain can have the opposite effect by causing “central fatigue” of the nervous system even when the muscles are still able to carry on.

“We can now see it is actually a surplus of serotonin that triggers a braking mechanism in the brain. In other words, serotonin functions as an accelerator but also as a brake when the strain becomes excessive,” said Professor Perrier, whose study is published in the Proceedings of the National Academy of Sciences.

“The discovery brings us a step closer to finding ways of controlling serotonin. In other words, whether it will have an activating effect or trigger central fatigue. It is all about selectively activating the receptors which serotonin attaches to,” Professor Perrier said.

“For selective serotonin re-uptake inhibitors [eg Prozac] we can possibly help explain why those who take the drugs often feel more tired and also become slightly clumsier than other people. What we now know can help us develop better drugs,” he said.

425runner
07-26-13, 08:04 PM
Is that so? Excess serotonin = tiredness? Hmm...I went to the doc complaining about feeling tired all the time and he puts me on Prozac?? Then it turns out the problem is with my adrenal glands producing too much cortisol which then leads to inflammation and depression. Vicious cycle...also I used to workout (lift weights) twice a week before starting with Prozac but then I got very, very weak....everything became a drag. It would have cost me a job cause I was so out of it, couldn't focus on anything. Then I started taking extra Dexedrine which scared the hell out of me. Addiction is the last thing I need right now....yeah...SSRI's are not for everyone.


Maybe serotonin is not the reason you are anxious? Excess serotonin will make anyone tired.

ana futura
07-26-13, 08:08 PM
Is that so? Excess serotonin = tiredness? Hmm...I went to the doc complaining about feeling tired all the time and he puts me on Prozac?? Then it turns out the problem is with my adrenal glands producing too much cortisol which then leads to inflammation and depression. Vicious cycle...

A lack of serotonin can make you depressed, which will make you tired as well. It's all about finding the right balance for the individual. But as a general rule, if SSRI's consistently make you tired, they probably aren't the right med for you. I think a lot of docs over prescribe SSRIs. They're a very good fit for many people, but they aren't the panacea they are made out to be.

425runner
07-26-13, 08:16 PM
True..my neurologist once told me that I may have to stay on Wellbutrin forever because it helps with anxiety/depression. But I don't like the side effects of these medications....trying some Rhodiola Rosea, ashwagandha, maca, tyrosine and Noopept right now.

Fortune
07-26-13, 08:43 PM
What do you consider a low dose? How long did it take you to get used to Zoloft? My main problem is depression/apprehension, will it help? Does it make you feel more cheerful or happy?

I take 50 mg/day, but I tend to react strongly to typical anti-depressant doses.

It took me a month or so.

It doesn't help as much with my depression. Even while on it, I was still assessed as having "moderate depression."

Newgirl804
07-27-13, 06:50 AM
It may be two much. I am on 40mg. I didnt even think they mae 5mg I started on 10. it helps a lot too. except the tired thing. I came in to the dr very nervous and on edge. I am trying taking it in the evenings to see if that helps at all. What else effects anxiety other than serotonin? I feel like if I could add something that targets a different area I could lower my dose of Prozac and be fine.

Fortune
07-27-13, 03:42 PM
I can't guess at the precise equivalence, but a 50 mg dose of Zoloft is not as powerful as a 50 mg dose of Prozac or more powerful than a 40 mg dose. Just looking at the amount doesn't tell you a lot in comparison.

From what I read, Prozac dosage goes from 20-80 mg and Zoloft goes from 50-200 mg.

425runner
07-27-13, 04:21 PM
I'm going back on Prozac tonight. I went through a heartbreak which was very emotional and the Prozac shut off all emotions but now I'm longing for something I can't have and it's very distracting. I mean I should be focused on studying and moving on but instead I keep obsessively checking my CP for text messages :( we used to work together and it's just soooo hard to work alone now. At least I felt happy when on Prozac, nothing could bother me...I'll just go low and slow this time. Only 2.5 mg and will take a break if I get too drowsy.

It helped so much with avoidance, I went to see a dentist after 15 years....and even had some work done on my teeth. Something I'd normally ignore.

Rebelyell
07-27-13, 07:37 PM
Im always so tired that no matter how much I sleep I am still tired n wanna get more sleep.im confused if itsdepression or the meds? I have not too much motivation but the meds help me cope not be so sensitive to everything.

425runner
07-27-13, 08:46 PM
What are you taking? I'll be honest I really like how the Prozac makes me detached from everything and everyone, it's like living in la-la-land. Except it's not practical :scratch: cause I'm always tired while on it. So hard to deal with everyday life and try to be ambitious......


Im always so tired that no matter how much I sleep I am still tired n wanna get more sleep.im confused if itsdepression or the meds? I have not too much motivation but the meds help me cope not be so sensitive to everything.

BellaVita
07-27-13, 08:52 PM
I'm going back on Prozac tonight. I went through a heartbreak which was very emotional and the Prozac shut off all emotions but now I'm longing for something I can't have and it's very distracting. I mean I should be focused on studying and moving on but instead I keep obsessively checking my CP for text messages :( we used to work together and it's just soooo hard to work alone now. At least I felt happy when on Prozac, nothing could bother me...I'll just go low and slow this time. Only 2.5 mg and will take a break if I get too drowsy.

It helped so much with avoidance, I went to see a dentist after 15 years....and even had some work done on my teeth. Something I'd normally ignore.

:grouphug::grouphug::grouphug:

So sorry to hear you're going through that. Stay strong. I hope Prozac works well for you this time.

Rebelyell
07-27-13, 10:01 PM
Celexa 40 mg n wellbutrin 300mg er

Abi
07-27-13, 10:25 PM
I can't guess at the precise equivalence, but a 50 mg dose of Zoloft is not as powerful as a 50 mg dose of Prozac or more powerful than a 40 mg dose. Just looking at the amount doesn't tell you a lot in comparison.

From what I read, Prozac dosage goes from 20-80 mg and Zoloft goes from 50-200 mg.

As far as it is possible to make these comparisons:

50mg Zoloft = 20mg Prozac = 20mg Celexa = 7.5mg Lexapro.

Abi
07-27-13, 10:26 PM
Celexa 40 mg n wellbutrin 300mg er

:)

Celexa 40mg, Wellbutrin 150 SR x 2 {no ER / XL here}

Rebelyell
07-27-13, 11:05 PM
W out the meds im quite argumentive and cantankerous im also very agrophobic w out them.

Newgirl804
07-28-13, 09:01 AM
Well I was thinking maybe if I tried Effexor that would help. My other option would be to decrease the Prozac while possibly adding something like Buspar. Has anyone tried that? I feel like 20mg Prozac was enough to decrease my GAD. However my social anxiety was still bad and it was even worse on Stimulatants, since I would become preoccupied with thinking people thought I was acting funny. Sine I was actually looking them in the eye and looking slower. I am usually able to self soothe in social situations, but with stims my heart rate is already increased making me feel physically anxious and I want to alleviate it as soon as possible. Would something like Buspar help? I am not able to take any type if benzo I have awful reactions to them.

karbouris
07-28-13, 04:02 PM
luvox

Morango
07-29-13, 03:58 PM
I am taking sertralin. It makes me even more awake (wouldn't mind the sleepy effekt though, cause I'm experiencing insomnia...)

425runner
07-29-13, 07:43 PM
Really? How much are you taking and have you experienced any side effects at the beginning? I ain't gonna take Prozac anymore cause I watched video on youtube by Charles Parker, MD - specialist in ADHD and he says Prozac blocks the effects of Dexedrine, that's why people report their stims are not working when they take Dexedrine + Prozac. I don't wanna take Wellbutrin anymore cause of the many side effects it gives me. Zoloft was recommended and I may just try some....


I am taking sertralin. It makes me even more awake (wouldn't mind the sleepy effekt though, cause I'm experiencing insomnia...)

FocusPocus10
07-29-13, 08:28 PM
prozac doesn't seem to block dex and adderall in practice, at least in my case.

BrightFuture
07-29-13, 09:25 PM
I take Lexapro as well. Initially, I did get the sleepy side effect but it does go away after awhile (about a week for me). I also take Adderall.

hollywood
07-30-13, 10:54 PM
I just started taking Wellbutrin again . I don't really like it . It basically eliminates or prevents me from being fully able to use "executive functioning tasks " which involve planning and organizing that's what Wellbutrin screws with . I've only been taking it for 3 days or so . So I guess Zoloft is Kind of the best regarding no lack of motivating effect

Newgirl804
07-31-13, 11:32 AM
I have tried Wellbutrin and I hated it because it made me flat. My current ADHD meds are VyVanse in the am and Adderrall ir later in the day. I haven't noticed Prozac counter my ADHD meds in any way except one. I don't get "stuck" on stuff anymore. Like I am able to switch tasks because of the anti obsessive quality of Prozac. Still my focus and motor controll is better. I would rather increase my stims than try something that does not give me that comforted feeling. Since before I was on Prozac I did not care about life one way or the other. I was also so socially withdrawn it was making me depressed i am naturally an extremely extroverted person. I was just wondering if anyone had a positive experience similar to that of Prozac with another medication.

ana futura
07-31-13, 11:57 AM
Really? How much are you taking and have you experienced any side effects at the beginning? I ain't gonna take Prozac anymore cause I watched video on youtube by Charles Parker, MD - specialist in ADHD and he says Prozac blocks the effects of Dexedrine, that's why people report their stims are not working when they take Dexedrine + Prozac. I don't wanna take Wellbutrin anymore cause of the many side effects it gives me. Zoloft was recommended and I may just try some....

I'm not sure if he said this was an across the board thing though. I think the point of his video is that if a patient experiences this problem, and they are on Prozac and amps, than Prozac might be to blame.

Just putting that out there for everyone who's saying "it doesn't block my Dexedrine." It's a case by case thing, based on your physiology, at least that's what it sounded like to me, although I haven't seen the video in a while.

425runner
07-31-13, 07:33 PM
Well, I took 2.5mg Prozac last night and plan on doing so until I start feeling overly sedated, the natural therapies suppressed anxiety but I didn't have any emotions at all...like I'd stare at the computer and not think, or do stupid things without even realizing it. The Prozac helps me be more aware but also makes me tired...so I started taking Wellbutrin XL 150 in the afternoon to stay productive.

This time around I am keeping a journal.

ana futura
07-31-13, 10:18 PM
This time around I am keeping a journal.

That's a really good idea. It's so hard to evaluate yourself.

hollywood
08-02-13, 12:20 AM
I think Prozac for sure works . I get pretty stuck on things , a negativf feedback loop or just on a negativf thing or even a commodity I'm selling . On Prozac I can vary that up snd eradicate it

Newgirl804
08-02-13, 07:09 AM
Well I met with my dr again, and after quite some trial and error I am still on Prozac 40mg at night, I was actually scared to come off of it because I had become so anxious I was phobic in certain cases. My mother never treated my ADHD as a child she just tried to "discipline" it out of me, and her "discipline" left me one frightened adult!!! I could never understand how when I was trying SO hard to be good I was always getting in trouble for fighting and talking in class or forgetting my homework. I just added another Adderrall to the mix, and that seems to work just fine. I feel more like my outgoing self, but a little less all over the place :)

425runner
08-02-13, 07:48 PM
Ha..ha..I had the same issues as a child. My parents were always onto me for fighting in school, skipping classes cause I thought they were boring, interrupting the teacher, not being on time etc. no wonder my self esteem is low...

I didn't get treatment until I was 34 and it has made a huge difference. Especially now that I found a medication which works and has no side effects.

Prozac truly is the best, I can skip a day or two with no side effects.


Well I met with my dr again, and after quite some trial and error I am still on Prozac 40mg at night, I was actually scared to come off of it because I had become so anxious I was phobic in certain cases. My mother never treated my ADHD as a child she just tried to "discipline" it out of me, and her "discipline" left me one frightened adult!!! I could never understand how when I was trying SO hard to be good I was always getting in trouble for fighting and talking in class or forgetting my homework. I just added another Adderrall to the mix, and that seems to work just fine. I feel more like my outgoing self, but a little less all over the place :)

hollywood
08-09-13, 11:48 PM
Prozac , Effexor or cymbalta

Darksanity
08-12-13, 10:35 PM
Zoloft (sertraline) at 50mg didn't make me tired and worked wonders, until it pooped out after about a year... :scratch: And damn the sexual sides suck!

Lexapro (escitalopram) even at a tiny dose of 2.5mg made awfully tired, lethargic, and gave me a general feeling of exhaustion (even if I didn't do ****).

I kinda wish I could get Zoloft to work again like the first time I took it... :(

Anyway now I'm thinking going with a Luvox (fluvoxamine) + buspirone combo. I think Luvox is the oldest SSRI but the fact it is a potent sigma agonist and one of the few drugs approved for OCD (which is the main source of my anxiety) makes it interesting. Adding buspirone in low dose can help mitigate SSRIs' side effects. Also, buspirone may increase dopamine synthesis through antagonism of D2 presynaptic autoreceptors thus improving response to stimulants buy having more dopamine available to be released. Sounds good doesn't it? :) See studies below.

Indian J Exp Biol. 2008 Oct;46(10):704-14.
Dose-dependent response of central dopaminergic systems to buspirone in mice.
Jadhav SA, Gaikwad RV, Gaonkar RK, Thorat VM, Gursale SC, Balsara JJ.
Department of Pharmacology, Krishna Institute of Medical Sciences, Karad 415110, India.

Abstract
Buspirone, a partial agonist of 5-hydroxytryptamine autoreceptors, preferentially blocks the presynaptic rather than the postsynaptic D2 dopamine (DA) receptors. Behavioural effects of a wide dose range of buspirone were therefore studied in mice. Buspirone at 0.625 to 5 mg/kg ip induced stereotyped cage climbing behaviour which was antagonized by pretreatment with haloperidol, alpha-methyl-p-tyrosine and small doses of apomorphine. Buspirone at 10, 20 and 40 mg/kg ip induced catalepsy and antagonized oral stereotypies induced by high doses of apomorphine and methamphetamine and apomorphine-induced cage climbing behaviour. The findings indicate that buspirone at 0.625 to 5 mg/kg selectively blocks the presynaptic mesolimbic D2 DA autoreceptors and releases DA which stimulates the postsynaptic mesolimbic D2 and D1 DA receptors and induces cage climbing behaviour. Buspirone, at 10, 20 and 40 mg/kg blocks the postsynaptic striatal and mesolimbic D2 and D1 DA receptors. Pretreatment with 1-tryptophan, dexfenfluramine and fluoxetine antagonized buspirone induced cage climbing behaviour and potentiated buspirone induced catalepsy. Pretreatment with trazodone, mianserin and p-chlorophenylalanine potentiated buspirone induced cage climbing behaviour and antagonized buspirone induced catalepsy. The results indicate that drugs which influence the activity of central serotonergic systems modulate the intensity of buspirone induced cage climbing behaviour and catalepsy.

PMID: 19024168 [PubMed - indexed for MEDLINE]
Indian J Physiol Pharmacol. 2007 Oct-Dec;51(4):375-86.
Effects of buspirone on dopamine dependent behaviours in rats.
Dhavalshankh AG, Jadhav SA, Gaikwad RV, Gaonkar RK, Thorat VM, Balsara JJ.
Department of Pharmacology, Krishna Institute of Medical Sciences, Karad.

Abstract
Buspirone, a partial agonist of 5-hydroxytryptamine autoreceptors, selectively blocks presynaptic nigrostriatal D2 dopamine (DA) autoreceptors. At doses which antagonised action of apomorphine in biochemical presynaptic nigrostriatal D2 DA autoreceptor test systems buspirone neither induced catalepsy nor antagonised apomorphine-induced turning behaviour in rats indicating that at these doses buspirone does not block postsynaptic striatal D2 and D1 DA receptors. This study determines whether at high doses buspirone blocks postsynaptic striatal D2 and D1 DA receptors and provides behavioural evidence for selective blockade of presynaptic nigrostriatal D2 DA autoreceptors by smaller doses of buspirone. We investigated in rats whether buspirone induces catalepsy and effect of its pretreatment on DA agonist induced oral stereotypies and on cataleptic effect of haloperidol and small doses (0.05, 0.1 mg/kg, ip) of apomorphine. Buspirone at 1.25, 2.5, 5 mg/kg, ip neither induced catalepsy nor antagonised apomorphine stereotypy but did potentiate dexamphetamine stereotypy and antagonised cataleptic effect of haloperidol and small doses of apomorphine. Buspirone at 10, 20, 40 mg/kg, ip induced catalepsy and antagonised apomorphine and dexamphetamine stereotypies. Our results indicate that buspirone at 1.25, 2.5, 5 mg/kg blocks only presynaptic nigrostriatal D2 DA autoreceptors while at 10, 20, 40 mg/kg, it blocks postsynaptic striatal D2 and D1 DA receptors. Furthermore, buspirone at 1.25, 2.5, 5 mg/kg by selectively blocking presynaptic nigrostriatal D2 DA autoreceptors, increases synthesis of DA and makes more DA available for release by dexamphetamine and during haloperidol-induced compensatory 'feedback' increase of nigrostriatal DAergic neuronal activity and thus potentiates dexamphetamine stereotypy and antagonizes haloperidol catalepsy.

PMID: 18476392 [PubMed - indexed for MEDLINE]

My only issue is the fact that Luvox appears to have a whole bunch of potential drug interaction since it inhibits many liver enzymes, including the enzyme responsible for metabolizing buspirone... While I'm pretty sure with proper dose adjustment this shouldn't be a problem, I doubt my doctor will agree when he sees the "drug interaction alert" on his computer. :rolleyes:

tambourine-man
08-16-13, 10:06 PM
Really? How much are you taking and have you experienced any side effects at the beginning? I ain't gonna take Prozac anymore cause I watched video on youtube by Charles Parker, MD - specialist in ADHD and he says Prozac blocks the effects of Dexedrine, that's why people report their stims are not working when they take Dexedrine + Prozac. I don't wanna take Wellbutrin anymore cause of the many side effects it gives me. Zoloft was recommended and I may just try some....


Prozac does not block the effects of stimulants in a literal sense, but it will often make them not work how they should. Let me explain. Most SSRIs inhibit CYP2D6, a liver enzyme needed to break down amphetamine. Paxil and Prozac are especially bad about this. Zoloft, Celexa, and Lexepro are better options. Cymbalta and Effexor XR inhibit CYP2D6 while Pristiq does not.

I had to discontinue Prozac and Paxil because of this. The amphetamine seems to build up in my system when I take Prozac or Paxil, making me especially tolerant to the positive effects and especially sensitive to the negative ones.

Greyhound1
08-16-13, 11:44 PM
I found that nothing worked for me. I tried every SSRI there was for about 12 years and only got worse. I started taking them for panic attacks that started right after my best friends death. They left me depressed, more anxiety and incredible fatigue. They caused a vicious cycle. They made me feel okay for about the first 6 mos. after that I started going down hill. Once that happens you think well, I must need more to feel like I did and the Dr. was more than happy to increase the dose. When that doesn't work you, you run back to the Dr. and he says here try this new one it might work. The best thing I did was to get off them. Finally, after being diagnosed with Adhd and taking adderall I have realized that I was always treating just the symptoms. Once I started getting my Adhd under control I got my mind back (at least sometimes) and my energy back without nearly as much anxiety. This has given me the strength and energy I need to get better and feel better because Adhd was the cause of my problems. Be careful with the SSRI's they may help temporarily but dealing with the real cause will work much better in the long run. I never found one that didn't seem to make me tired and out-of-it most of the time.

jose40
12-30-13, 12:29 AM
I have tried Wellbutrin and I hated it because it made me flat. My current ADHD meds are VyVanse in the am and Adderrall ir later in the day. I haven't noticed Prozac counter my ADHD meds in any way except one. I don't get "stuck" on stuff anymore. Like I am able to switch tasks because of the anti obsessive quality of Prozac. Still my focus and motor controll is better. I would rather increase my stims than try something that does not give me that comforted feeling. Since before I was on Prozac I did not care about life one way or the other. I was also so socially withdrawn it was making me depressed i am naturally an extremely extroverted person. I was just wondering if anyone had a positive experience similar to that of Prozac with another medication.
Hi Im new to the forum ive been on prozac for depression, mania, anxiety and ocd also seroquel as a sleep aid and so far so good ive been on it for about 6 years and im thinking of talking to my Doctor about adhd ive always had trouble paying attention focusing and caring out task it so hard finding a Dr that really cares about you and not just shoving another pill down your throat.

abk2014
03-16-14, 03:11 AM
I'm pretty sensitive to medications and I've found Celexa at just 10 mg. to help a lot with my OCD and depression. I don't feel too tired at that dose, but for me it works. For ADHD-PI I first tried Strattera and Wellbutrin, but neither really did the trick. I stayed on the Wellbutrin (150 mg.) to counteract the sexual side effects of the Celexa. It took me a while to venture into stimulants because I was worried they would worsen the OCD. I tried Adderall briefly (20 mg.) which worked decently but I didn't like the ups and downs. It actually DECREASED my anxiety because I felt calmer and less prone to forgetfulness, accidents, and losing track of conversations. I'm trying Vyvanse next at 20 mg. We'll see how it goes! For anti-depressants, I do recommend the Celexa/Wellbutrin combo, provided that the Wellbutrin doesn't worsen your anxiety!