View Full Version : NMDA and neuroplasticity


Amtram
11-07-13, 04:56 PM
From the Journal of Cell Biology, Synaptic NMDA receptor stimulation activates PP1 by inhibiting its phosphorylation by Cdk5 (http://jcb.rupress.org/content/early/2013/10/28/jcb.201303035)

Again, unfortunately, only a summary. However, it looks like an interesting case for NMDA agonists improving plasticity, which could at least partly explain their role in improving memory in patients with neurodegenerative diseases.