View Full Version : Paradoxical effect of stimulants in ADHD

02-12-16, 09:53 AM

Paradoxical cortisol responses to dextroamphetamine in endogenous depression.------- * --------
slow balance fast

ADDer depessed - corrected with amphetamine -> no stress/speed response

------- ^
------- normal - stressed / speeds on amphetamine

Trapped in a spectrum between

depression (too slow) and anxiety (too fast)

Very much looks like dopamine regulates our 'tempo' or 'clock'.

Central clock orchestrates peripheral clocks which govern whole body functioning.
Clock-Talk: Interactions between Central and Peripheral Circadian Oscillators in Mammals.

Regular conclusion - attaining balance (between wildly fluctuating 'antagonistic' opposites) appears to be the goal.