View Full Version : Paradoxical effect of stimulants in ADHD


SB_UK
02-12-16, 09:53 AM
http://www.ncbi.nlm.nih.gov/pubmed/7197513

Paradoxical cortisol responses to dextroamphetamine in endogenous depression.------- * --------
slow balance fast

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ADDer depessed - corrected with amphetamine -> no stress/speed response

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------- normal - stressed / speeds on amphetamine

Trapped in a spectrum between

depression (too slow) and anxiety (too fast)

Very much looks like dopamine regulates our 'tempo' or 'clock'.

Central clock orchestrates peripheral clocks which govern whole body functioning.
Clock-Talk: Interactions between Central and Peripheral Circadian Oscillators in Mammals.
http://www.ncbi.nlm.nih.gov/pubmed/26683231

Regular conclusion - attaining balance (between wildly fluctuating 'antagonistic' opposites) appears to be the goal.