View Full Version : Acetyl-L-carnitine (ALC) for inattentive ADD?


ToInfinity
01-24-17, 11:09 AM
ALCAR. Have anyone tried this? It's easy to get, just over the counter and easy to tolerate. From the study, results show that there's benefits for the inattentive type over the combined type.

"There was significant (p = 0.02) moderation by subtype: superiority of ALC over placebo in the inattentive type, with an opposite tendency in combined type."

"It deserves further exploration for possible benefit specifically in the inattentive type."

https://www.ncbi.nlm.nih.gov/pubmed/18315451


Also, healthy individuals over in forums sees it as a nootropic and use it for concentration.

This is something worth a look at.

Fraser_0762
01-24-17, 03:02 PM
Haven't tried that one (yet). But had some very mild success with L-Tyrosine when taken in combination with Caffeine. I find that it takes the edge of the Caffeine a little bit, while still retaining the mild benefits.

20thcenturyfox
01-25-17, 11:36 PM
ALCAR. Have anyone tried this? It's easy to get, just over the counter and easy to tolerate. From the study, results show that there's benefits for the inattentive type over the combined type.

"There was significant (p = 0.02) moderation by subtype: superiority of ALC over placebo in the inattentive type, with an opposite tendency in combined type."

"It deserves further exploration for possible benefit specifically in the inattentive type."

https://www.ncbi.nlm.nih.gov/pubmed/18315451


Also, healthy individuals over in forums sees it as a nootropic and use it for concentration.

This is something worth a look at.

This use of ALC was new to me, so thank you for raising this. I've used small amounts of ALC for years, either for peripheral neuropathy or general brain health, but never specifically for ADHD, and never noticed any effect on concentration. Nor had I ever seen ALC mentioned for ADHD or Migraine.

But then I never tried it in the large quantities mentioned in the OP's 2007 study...which if I understand "b.i.d." as meaning "twice daily" amount up to 3 grams per day for 4 months! However this was only from the abstract, not the full text, and is getting rather old.

So I looked around for some follow up and found the abstract of a 2011 study which appears intended to follow up the OP's study, but concludes there was no appreciable effect on ADHD. https://www.ncbi.nlm.nih.gov/pubmed/21336630 .

BUT here's something strange: the 2nd article only mentions 500-1500 mg per day--nothing about b.i.d. thus implying only half the original dosage. But again, I only found the abstract for free, not the full text, so can't tell if this was a true discrepancy or otherwise explained.

However, since safety doesn't seem to be an issue with ALC, the larger quantity certainly might be worth trying for a time.