View Full Version : Running out of options, nothing seems to work...what next?


Obsessive_ADD
02-18-17, 06:02 PM
I have tried all of the traditional psychiatric medications indicated for ADHD in the USA as far as I know. Nothing seems to really help with a few very temporary moments of success. I'm diagnosed with ADD-PI, Generalized Anxiety Disorder and mild OCD. My main problem is processing information - I can sit in a class and be unable to follow even if I know the material to some degree or have as much or more pre-requisite knowledge compared to other students. Same kind of problem with reading, I have to stop and think hard about stuff and re-read it a lot to process the meaning. Less complex and familiar contexts aren't nearly as tedious for me to read.

Does anyone have any idea what I could try next? I've tried so far:

Adderall - helped significantly with concentration for the first couple days
Dexedrine
Desoxyn
Concerta
Ritalin
Focalin

Strattera
Intuniv
Tenex
Provigil

Buspar - helped noticeably with concentration/being engrossed in a task. Effect lasted for only a couple days after having been on it for ~2-3 weeks
Lexapro
Zoloft
Lithium
Prozac
Pristiq
Abilify
Cymbalta
Effexor
Lamictal
Namenda
Clomipramine - helped significantly with concentration and empathy for the first couple days
Haldol
Luvox - helped slightly at times with getting in the "zone" if something was particularly stimulating, such as a video game.
Wellbutrin

Methylcobalamin - helped significantly with concentration and anxiety for the first couple days, dosage increase led to the positive effects returning to a lesser degree.
Cyanocobalamin
SAM-E
Tryptophan - helps with concentration sometimes, other times makes my mind really slow, wakes me up sometimes
L-Tyrosine - helps with concentration sometimes, other times makes me forgetful
NAC - sort of helped with concentration the first couple weeks, eventually it started to make me feel kind of bad ~20 minutes after taking it.
Pramiracetam
Melatonin - helps with concentration a little sometimes, often wakes me up after taking it, the following day my brain is better able to hold information in mind.

Little Missy
02-18-17, 07:39 PM
Go back and try them again, maybe this time it'll work. :confused:

dvdnvwls
02-18-17, 08:33 PM
Melatonin helping with memory points to a sleep problem of some kind. Try getting that investigated.

Swissy
02-18-17, 10:58 PM
I suggest trying the ones that helped temporarily, and when they stop working increase the dose instead of giving up on it.

sarahsweets
02-19-17, 06:28 AM
I think you should start over but only try one thing at a time. A lot of times people try a medication but more than one at a time so they are not able to discern which one is causing the problems or helping/not helping. Its also important to try different doses before you cross one of the list.

Jenn1202
02-19-17, 08:40 AM
Have you tried Vyvanse? I think that's the only ADD stimulant u don't have listed on there.

Obsessive_ADD
02-20-17, 11:24 AM
Have you tried Vyvanse? I think that's the only ADD stimulant u don't have listed on there.

Actually, I have. I forgot to list it. Felt like a weaker Adderall without the initial positive effect.

Obsessive_ADD
02-20-17, 11:27 AM
Go back and try them again, maybe this time it'll work. :confused:

Are you kidding? Any in particular? I've been on Adderall 5 times, B12 several times, Straterra 3 times, Ritalin 3 times and Pristiq twice. SSRIs are a pain to come on and off of. Would probably take 5+ years to try everything again if I was quick about it.

Obsessive_ADD
02-20-17, 11:29 AM
I think you should start over but only try one thing at a time. A lot of times people try a medication but more than one at a time so they are not able to discern which one is causing the problems or helping/not helping. Its also important to try different doses before you cross one of the list.

I've tried virtually all of the medications on the list by themselves at some point. The only exception would be Intuniv which I took with Clomipramine. I've also tried them in conjunction with others. This has taken over 10 years.

UPDATE to original post, I think I should remove Tenex from the list, can't find in my records when I took it. I did find Intuniv (long acting version) but not Tenex.

Obsessive_ADD
02-20-17, 11:40 AM
Melatonin helping with memory points to a sleep problem of some kind. Try getting that investigated.

Yes, I have always had difficulty falling asleep at will. But I can also sleep for 16+ hours at a time as well. Not sure how I would get it investigated...I told my psychiatrist I have always had sleep problems and all he did was lower the Adderall I was on. This didn't help. Doctors don't seem to want to listen when things aren't going as the books says they should. Ironically, Adderall actually makes me drowsy sometimes.

Little Nut
02-20-17, 03:57 PM
Obsessive, based on the list and the time it took to evaluate each, I would be EXTREMELY frustrated. TBH I would dump that in the prescribing physicians lap and ask him/her, "what next?" I would also question the diagnoses. (wrong mental disorders, missed mental disorder, missed non-mental disorder....) and point out to your Psychiatrist these concerns and that you would like a well thought out response from him/her at a future appointment. (Being a list guy, I would have summed everything up in writing and given it out at the beginning.) If the Doc's response isn't acceptable to you, get a copy of your files and find another Doc (another pscyh, internist, your current PCP).

acdc01
02-20-17, 08:27 PM
get someone else to take notes in class for you. Less reading than a book. That's what I did in college. Wouldn't have passed without. I hadn't tried as many meds as you but the ones I did would never have helped me to the point where I could pay attention in class had I known I had adhd back then.

Cyllya
02-24-17, 12:37 AM
What's the highest Adderall dose you took? "Helps, but only for a few days" seems to be a common result for people taking a low dose. Doctors will normally start you on a lower dose than the one that will actually be best.

But the results from the Adderall are also a hint of a possible sleep problem....

Yes, I have always had difficulty falling asleep at will. But I can also sleep for 16+ hours at a time as well. Not sure how I would get it investigated...I told my psychiatrist I have always had sleep problems and all he did was lower the Adderall I was on. This didn't help. Doctors don't seem to want to listen when things aren't going as the books says they should. Ironically, Adderall actually makes me drowsy sometimes.

You could get a sleep study (https://en.wikipedia.org/wiki/Sleep_study) if you haven't already. If your insurance allows you to go to specialists without a PCP referral, you might just google "sleep clinic" and call someone who shows up in the results.

finallyfound10
02-24-17, 03:07 AM
Maybe it's more the subject matter of the classes?

Ex. I have a degree in Education that I found rather easy to obtain and I was undiagnosed and on no meds but my second degree in Nursing was so difficult and I was diagnosed and on Concerta and an antidepressant for a lot of the time I was in school!

ohlookakitty
02-24-17, 10:25 AM
How is your overall sleep? Do you dream a lot, known to snore, and just feeling lethargic every morning? Some anxiety/ADHD can also be caused by sleep apnea which contribute to ADHD like symptoms as well.

What is your everyday diet like? Any allergies?

You honestly sound like exactly like me and if I don't get quality sleep I'm all over the place in processing information.

dvdnvwls
02-24-17, 12:20 PM
ohlookakitty:
Actually, anyone who doesn't get quality sleep is all over the place in processing information - it's not you. :)

But throw in ADHD and obviously it's worse.

And you're still right about what you said.

funkymascot
03-02-17, 04:14 PM
Wellbutrin helps me tremendously for processing information. But considering the list of mess you've already tried I doubt it would work for you

dopaminerush
03-17-17, 12:44 PM
There is a lot of conditions which can be diagnosed as ADHD by itself or combination of few of them.

1-Sleep apnea, nasal congestion, snoring, central apnea, hypoventilation ...etc anything that can lower oxygen levels during sleep.

2-b12 deffiency or genetic disability to metylate b12...

3-iron deffiency

4-Brain damage from chronic exposure to 1-2-3

5-phtoestrogen exposure during pregnancy (they say but i dont know its true)

6- all 1 to 5 not even exist but all wrong shaped brain parts can come as a genetic disorder.

7- all of them...



if you have and stop first tree condiitons,you can reverse condition very good to a deggree but not completly.
if you have genetic + other factors together you can reverse it a little bit

if you have only genetic version, you cant do anything pernament about your condition.


plus :
there is a psychological condition caused by living alone, looking to computer monitor for 10 hours a day for years, not enoguh social interaction ... after a point your brain can forgot how to listen lessons, understand and applicate new info..etc
its like PIED. when jump on adhd drug some people need a lot of practise to use that dopamine to function like a normal human being.

sarahsweets
03-17-17, 04:35 PM
There is a lot of conditions which can be diagnosed as ADHD by itself or combination of few of them.

1-Sleep apnea, nasal congestion, snoring, central apnea, hypoventilation ...etc anything that can lower oxygen levels during sleep.

2-b12 deffiency or genetic disability to metylate b12...

3-iron deffiency

4-Brain damage from chronic exposure to 1-2-3
Can you elaborate on the brain damage part? I havent heard of b12 or iron deficiency causing brain damage.


5-phtoestrogen exposure during pregnancy (they say but i dont know its true)

6- all 1 to 5 not even exist but all wrong shaped brain parts can come as a genetic disorder.

7- all of them...


What do you mean by wrong-shaped brain?


if you have and stop first tree condiitons,you can reverse condition very good to a deggree but not completly.
If someone has legitimate brain damage, it can not be reversed.

if you have genetic + other factors together you can reverse it a little bit
Genetics cant be reversed.


if you have only genetic version, you cant do anything pernament about your condition.

I dont think it matters about brain damage or genetics. ADHD cant be permanently treated, the symptoms can be treated but not the actual disorder.

dvdnvwls
03-17-17, 04:39 PM
Massive deficiency in iron or B12 could probably cause brain damage. If you had a minor deficiency and corrected it in a reasonable time, that wouldn't occur.

Certainly even an ordinary deficiency of B12 causes lethargy and foggy thinking.

Lunacie
03-17-17, 08:03 PM
Did the doctor check for things like thyroid problems? Allergies? Depression?
They can cause symptoms that look like ADHD.

And sometimes we're not very objective observers of our own selves. If you
asked a friend/classmate/teacher if the meds were making a difference, you
might be pleasantly surprised.

dopaminerush
03-18-17, 07:52 AM
Can you elaborate on the brain damage part? I havent heard of b12 or iron deficiency causing brain damage.

Yes it can cause. There is not certain knowledge.

But its very complicated. And i think its apparent that its is causing some very bad things.

you can find some articles like this :
https://www.ncbi.nlm.nih.gov/pubmed/18790724
http://newsroom.ucla.edu/releases/diet-counts-iron-intake-in-teen-221542
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540447/

this is ferritin :
https://www.ncbi.nlm.nih.gov/pubmed/15583094


iron, b12 and sleep quality is very very essential for daily dopaminergic system recovery even zinc is important. Any impairment on those mechanisms can effect brain. If it continues chronicly it can give you pernament damage. It happened to me. Its speeding up your cognitive decline like crazy. i learned my defficiencies at 29 yo and it was too late for me. But on this forum there are a lot of young people dont know about iron and b12. I think every ADHD people MUST get a iron, ferritin and b12 test. This must be the first step before being a stimulant junky.
Even there is a lot of MISDIAGNOSED non adhd guys who have those conditions.

After starting taking tardyferon + hydroxycobalamin injections im far far better. Specially with prograstination and brain fog. On tests if i get bored on 7. question now im geting bored on 20. question. ...etc im still getting bored but im better now. if i got iron when i was 15 may be i wish be far better now. i was skinny as hell and lethargic.

so as you see i REVERSED some of my adhd symptoms a little bit pernamently :) but not reversed the damage. its impossible i think.

this is a good facility and i think there are a lot of guys who can benefit from this hoping on large amounts of oral cocain like metylphenidate and getting decompensation effect, they are distrupting their dopamin receptors. Some of them can solve their deffiencies and get away with far lower dosages.

if you are not responding to ritalin,adderal...etc may be it can be a misdiagnosed iron,b12,sleep problem. or combined with adhd.

iron in adhd
https://www.ncbi.nlm.nih.gov/pubmed/15583094

for sleep
http://www.youtube.com/watch?v=jgWLxWTaaro

i am one of those nasal congested childrens. nasal ceongestion is very very important for adhd. if you have this problem JUST SOLVE IT NOW GET SURGERY.

http://www.youtube.com/watch?v=vqgDW-KXH3Y

i dont know this guys is a snakeoil salesment or not but after i got radiofreq nasal turbninate reduction my adhd symtomps healed to a very good degree.
not complety but it healed to a degree.


What do you mean by wrong-shaped brain?



sorry for my english, wrong shaped brain : you know that adhd brains are looking a little bit different from others by some parts on scanned images.
just type ''adhd brain'' on google images.




If someone has legitimate brain damage, it can not be reversed.

Genetics cant be reversed.

I dont think it matters about brain damage or genetics. ADHD cant be permanently treated, the symptoms can be treated but not the actual disorder.

Yes im talking about this. But you are persistent at not understanding me. if your adhd is getting far heavier by these additional conditions you CAN REVERSE ONLY THE NONGENETIC PART.
cpap, iron, b12 is helping a lot of childs. if they are using 54mg they can get awat with 17mg concerta or milder guanfacine like drugs. after passing academic exams they can get away without taking those cocaine pills.
when Cognitive behavioral therapy added it can be far easier for kids and adults to get away with it.

sarahsweets
03-18-17, 10:22 AM
iron, b12 and sleep quality is very very essential for daily dopaminergic system recovery even zinc is important. Any impairment on those mechanisms can effect brain. If it continues chronicly it can give you pernament damage. It happened to me. Its speeding up your cognitive decline like crazy. i learned my defficiencies at 29 yo and it was too late for me. But on this forum there are a lot of young people dont know about iron and b12. I think every ADHD people MUST get a iron, ferritin and b12 test. This must be the first step before being a stimulant junky.
Even there is a lot of MISDIAGNOSED non adhd guys who have those conditions.

Do you mean lack of b12 or iron? I ask because I have to take supplements due to nutritional issues so I am trying to understand if you mean too much or lack of enough things like b12 and iron.

this is a good facility and i think there are a lot of guys who can benefit from this hoping on large amounts of oral cocain like metylphenidate and getting decompensation effect, they are distrupting their dopamin receptors. Some of them can solve their deffiencies and get away with far lower dosages.

Are you saying that methylphenidate and cocaine are the same things?
i am one of those nasal congested childrens. nasal ceongestion is very very important for adhd. if you have this problem JUST SOLVE IT NOW GET SURGERY.
Surgery for what?




Yes im talking about this. But you are persistent at not understanding me. if your adhd is getting far heavier by these additional conditions you CAN REVERSE ONLY THE NONGENETIC PART.
I am not deliberately trying to not understand you, I really do want to understand you but am having trouble. At the same point I dont want to scare someone who is new by mentioning things like this if they are not true or at least easy to understand.

cpap, iron, b12 is helping a lot of childs. if they are using 54mg they can get awat with 17mg concerta or milder guanfacine like drugs. after passing academic exams they can get away without taking those cocaine pills.
when Cognitive behavioral therapy added it can be far easier for kids and adults to get away with it.
I wish you would stop referring to medication as cocaine pills. I find it very offensive.

dopaminerush
03-18-17, 04:45 PM
Yes. i think you should get a blood test before using them.

of course its not same its similar.

Generally serious nasal congestion needs removal of conchas, polyps or septum bone.

My main language is not english may be im choosing wrong words to write and meaning going to another direction .