View Full Version : Am I missing something?(Methylphenidate vs. Amphetamines)


Emre22
07-03-17, 01:24 PM
I have started using concerta 2 years ago , i started with 36mg then my doctor increased my dosage to 54mg.

I have read a lot about ADHD, I read a lot about medications.

Ok let me enter into topic

I have doubt in my mind which annoys me

Methylphenidate is not an amphetamine salt, it is chemical structure and mechanism is more similar to cocaine

Mechanism of amphetamines are really different than both

Amphetamines can induce relase of dopamine but Methylphenidate is mostly working by inhibition of dopamine re-uptake


I am not a professional ofc

But i would like to ask people who have experience, which one is better do you think?

We dont have amphetamine salts in where i live , even if my doctor wants to prescripe it he cant
So if i had a chance of using amphetamine salts( adderall,dexedrine , vyanse , desoxyn etc.)
It could help me more than Concerta ?

Lunacie
07-03-17, 01:35 PM
Both amphetamine and methylphenidate have a long history of improving adhd
symptoms. At this time there is no way to predict which will work best for any
individual. Although GeneSight testing is showing some promise.

Emre22
07-03-17, 01:47 PM
Both amphetamine and methylphenidate have a long history of improving adhd
symptoms. At this time there is no way to predict which will work best for any
individual. Although GeneSight testing is showing some promise.


but we can have statistics which shows how many people got better after switching to concerta from amphetamines or reverse of it

For instance,
Lets say poll includes opinion or experience of 100 people

60 of these people were using methylphenidate but they switched to amphetamines due to methylphenidate's weak effectiveness

20 of these people were using methylphenidate , they have tried to switch to amphetamines but it didnt go well

20 of these people were using amphetamine salts, they have switched to methylphenidate and methylphenidate worked better for them

%60-40

it was just example

Emre22
07-03-17, 01:51 PM
Both amphetamine and methylphenidate have a long history of improving adhd
symptoms. At this time there is no way to predict which will work best for any
individual. Although GeneSight testing is showing some promise.

It is so weird , amphetamines are prescribed on most of countries
And mine is an exception

I have a doubt in my mind , Turkish authorities didnt approve amphetamines due to their conservative worries

It isn't paranoia, because here people are capable of doing it.
They have no idea about controlled substances , they only see them as monsters
Full of bigotry etc.

Thats why i really want to have an idea about comparison of both medicines

aeon
07-03-17, 02:35 PM
For me, I'm not sure if amphetamine is better than methylphenidate as it regards efficacious treatment of my ADHD, but I tolerate the side-effects of amphetamine better, and was the reason for my switch.


Cheers,
Ian

Lunacie
07-03-17, 03:16 PM
but we can have statistics which shows how many people got better after switching to concerta from amphetamines or reverse of it

For instance,
Lets say poll includes opinion or experience of 100 people

60 of these people were using methylphenidate but they switched to amphetamines due to methylphenidate's weak effectiveness

20 of these people were using methylphenidate , they have tried to switch to amphetamines but it didnt go well

20 of these people were using amphetamine salts, they have switched to methylphenidate and methylphenidate worked better for them

%60-40

it was just example

Until there is a way to tell which med a person will respond best to, there's
not much point in knowing which helps the largest number of people. You
may find you're in the minority, or not. :umm1:

This study shows no real difference in numbers helped by either one of the
meds. https://www.ncbi.nlm.nih.gov/pubmed/10405498