View Full Version : Difference in generic effectiveness between dosage?


Swissy
08-10-17, 10:00 AM
Odd question. Given the fact that genetics can vary in effectiveness, I was wondering if anyone has experienced the dosage size within one generic brand arying. I was considering asking for 15mg IR, but the 10mg IR Sandoz has been good (half of he time.) I would rather stick with good 10mg that works sometimes than bad 15mg if that makes sense. Any personal experiences you can share? (I know in wh end it varies for each individual)

wonderboy
08-10-17, 12:45 PM
As bizarre as this may sound, for every individual that supports one specific generic company, I guarantee you --
you will find another one that hates that specific pharmaceutical company

Little Missy
08-10-17, 12:49 PM
It a weird gig. A roll of the dice. I just try to do the best I can.

sarahsweets
08-11-17, 07:10 AM
Generic sandoz adderall xr 5mg and 10mg did not help me but the sandoz xr 15mg does.I also taken adderall xr 20 by global and I love it.

Snoopy10
08-11-17, 09:24 AM
I've only ever been on Teva and it works for me

Synezthesia
08-12-17, 06:59 PM
There are couple that seem to be universally hated... Aurobindo and Mylan come to mind. The rest is a mixed bag. Personally I always liked CorePharma, but sadly it looks like they ceased manufacturing of their generic IR.

westcoastmuscle
08-23-17, 08:21 PM
So if I am getting this straight I should be filling my 30mg IR script asking for Global because they are supplied and use the same formula as Shire the original makers of Adderall...correct? Not for XR but IR as well...correct? Second best Sandoz IR.

I have been taking Aurolife for the past 2-3 thinking I needed to try a new medication because they didn't seem to focus me. I have a protocoled from my doctor 5:30 AM First dosage. Second dosage between 11AM/12PM. I didn't have the level of attention or concentration i normally would have. Thought it was me needing to change but after finding this site I think I have a WAY better understanding of the generic market and the importance of being selective.

Thank you:)

sarahsweets
08-24-17, 04:28 AM
If you get to ask and your pharmacy wont look at you like you are out of your mind, I personally would ask for global. At least in this one regard it is made by shire as well. Sandoz is hit or miss for me with the xr as I have said. I dont take the IR anymore and Shire as far as I know does not do IR meds. I think sandoz/EON does, and then the others mentioned by other people.

NYLAVE
08-31-17, 03:58 PM
I joined this forum to ask the same question. Started taking Adderall about two months ago for treatment resistant depression and am at 20mg x2 daily. I was taking Aurobindo 10mg pills from Ralphs pharmacy in Los Angeles, then switched to Aurobindo 20mg from CVS.

I had no idea that there were different generics and never considered that I would feel anything different from switching. The 20mg CVS version felt much speedier to me, felt nervous more than just awake and alert. However the depression was lifted about the same amount.

I researched a bit, learned there were different generic manufacturers, and thought I must have been prescribed a different generic. However I wasn't. Both were Aurobindo.

I'm considering going back to the 10mg version and see if I see a change when it's time to renew in a few weeks. Will update this then.

Swissy
08-31-17, 05:15 PM
Thanks guys. I think my question was misunderstood. I was asking if 15mg Sandoz would be same quality as 10mg Sandoz (IR). I know the generic brands vary in effectiveness for each individual, I was just wondering if anyone increased dosage (within same brand) and regretted it.

MyAchillesheel
09-03-17, 12:59 PM
Hi Swissy,

I know what you are getting at and the short answer is: YES there can be a difference when changing strength from 10mg to 15 mg within the same generic name (Sandoz) of medication.

I personally experienced this with Teva Adderall and with Watson generic Ritalin.

My doctor always said; "If you find a certain dose that always works within a certain brand (whether generic or name brand) stick with that dose. If you need more medication let's stick with the same dose and I will write a script for more and then have you cut the tablets in half to increase the individual dose from 10mg to 15mg."

So....yes, stick with what works. You may be perfectly fine if you change from the 10mg to the 15mg tablet....but if it doesn't work....then you have 30 days of lost productivity and lots of frustration...

Remember the KISS phrasse??....Keep It Simple Stupid... Just remember that next time you are thinking about a change....

You will be fine, but unless you have to... I wouldn't riskit for the biskit unless you have no choice..

In my case I found the Teva 15 mg IR tablets profoundly better and more stimulating than the 20 or 30 mg tablets. I still find that to still be the case even today.

In the case of Watson IR generic ritalin, I found the 5mg and 10mg tablets vastly superior to the 20mg tablets. Later I found that the 5 and 10mg tablets were made in an entirely different facility (Danbury Ct) than the 20ng tablets (Corona Ca). Not sure what the deal is today since Teva bought out Actavis who bought out Watson/Danbury.

So Swissy, my point and my wise old doctor's remain the same: Stick with what works....

All the best to you, your family, and loved ones.
-M

Swissy
09-03-17, 06:42 PM
Hi Swissy,

I know what you are getting at and the short answer is: YES there can be a difference when changing strength from 10mg to 15 mg within the same generic name (Sandoz) of medication.

I personally experienced this with Teva Adderall and with Watson generic Ritalin.

My doctor always said; "If you find a certain dose that always works within a certain brand (whether generic or name brand) stick with that dose. If you need more medication let's stick with the same dose and I will write a script for more and then have you cut the tablets in half to increase the individual dose from 10mg to 15mg."

So....yes, stick with what works. You may be perfectly fine if you change from the 10mg to the 15mg tablet....but if it doesn't work....then you have 30 days of lost productivity and lots of frustration...

Remember the KISS phrasse??....Keep It Simple Stupid... Just remember that next time you are thinking about a change....

You will be fine, but unless you have to... I wouldn't riskit for the biskit unless you have no choice..

In my case I found the Teva 15 mg IR tablets profoundly better and more stimulating than the 20 or 30 mg tablets. I still find that to still be the case even today.

In the case of Watson IR generic ritalin, I found the 5mg and 10mg tablets vastly superior to the 20mg tablets. Later I found that the 5 and 10mg tablets were made in an entirely different facility (Danbury Ct) than the 20ng tablets (Corona Ca). Not sure what the deal is today since Teva bought out Actavis who bought out Watson/Danbury.

So Swissy, my point and my wise old doctor's remain the same: Stick with what works....

All the best to you, your family, and loved ones.
-M

Thank you, this is just the Info I was seeking! My gut told me to just stick with the 10mg pills.

wonderboy
09-03-17, 09:16 PM
Thanks guys. I think my question was misunderstood. I was asking if 15mg Sandoz would be same quality as 10mg Sandoz (IR). I know the generic brands vary in effectiveness for each individual, I was just wondering if anyone increased dosage (within same brand) and regretted it.

In my opinion, increasing your dose by 5 mg would be -very subtle- in terms of you noticing an increase in its efficacy, regardless of the generic company

There is always the possibility of an anomaly in all cases

Never ends
09-11-17, 11:57 AM
So I just got a 10 mg IR added for an afternoon dose, the brand is mallan, anyone had bad side effects from it with an XR of a morning?

Swissy
09-11-17, 03:45 PM
I never heard of Mallan. If it's a spelling error, I can tell you that my doctor stamps my scripts "NO MYLAN".

MyAchillesheel
09-12-17, 01:49 AM
If it says "Mallan" on the prescription bottles label it is most likely Mallinckrodt generic adderall in a white octagon/stop sign looking pill.

However, like Swissy mentioned earlier if you misspelled then it most certainly could be "Mylan".

In respect to side effects:

If you have Mallinckrodt my experience was simply a very weak generic form of adderall. I had no bad side effects at all other than requiring an increase in dosage.

If you meant Mylan, I unfortunately have no experience with that generic.

Please keep us all posted. Hopefully regardless of anyones experience you have good results.

Please let us know.

All the best to you.
-M

Never ends
09-12-17, 02:16 PM
It is mallin, auto correct strikes again, I took one yesterday and it seemed to do its job, hopefully it stays that way.

nanajoy
09-29-17, 07:00 PM
As bizarre as this may sound, for every individual that supports one specific generic company, I guarantee you --
you will find another one that hates that specific pharmaceutical company

But...but...that's perfectly normal, right? Sort of like coffee, right? I love coffee. I hate ALL starbucks coffee, though.