View Full Version : Ritalin - Instant to modified release transition


Donker94
09-27-17, 09:51 AM
I'm a 23 year old male who was diagnosed with ADHD about two months ago. My main issues are primarily focus, recklessness, fatigue, hypersomnia.

When I first started ritalin, I was given the instant release version starting at 5mg x1/day, then 5mg x2/day, and on the third day I did 5mg x3/day and stayed there for about 2 weeks.
I immediately noticed a difference in focus, don't know how to explain the next part, but it felt like my eyes were finally open. I was very effective during the day, and I felt exhausted in the evening which helped me sleep, my sleep was also drastically reduced, I felt good and replenished after 6-8 hours of sleep compared to my usual 10-12 hours.
After about 2-3 weeks the effects started to diminish. Concentration was a little worse, but far better then it was before I started ritalin, slept for 10-12 hours again.
Upped the dose to 10mg x1, 10mg x2 and after about a week 10mg x3 which worked superb. I had zero side effects from it except for the comedown "depression". It also supressed my appetite which is a good thing since I often started eating and got an extreme feeling of hunger when I was bored.

ANYWAYS, after another 2-3 weeks(recently) my doc put me on some modified release Ritalin capsules, 30mg. I literally didn't feel anything, felt like I did before the meds. Started to think he gave me placebo or something. Vision was blurry like before and it was hard to stay focused. No energy, excessive sleep again, intolerance to medium-high sounds which resulted in aggresiveness. Some mornings, I woke up, turned on the coffee machine, and as soon as it started making loud noises I just felt like I was about to explode and just tear down the whole kitchen.

What I would like to know is; how is it possible for the same drug to have such complete different effects? Doc recommended I up the dose to 50mg x1, but I have little faith in this particular med. I will do as he say nonetheless.
Has anyone here experienced similar effects from transitioning? Did upping the dose fix it? Did you switch back to instant release, and did it work as it did before? Thank you and sorry for the wall of text.

MyAchillesheel
09-27-17, 04:27 PM
Donker94,

You sound very similar to me. So here are some suggestions and thoughts.

Yes, without question the extended version of any stimulant may work better or worse depending upon your metabolism.

None of the extended release products for Ritalin or adderall ever worked well for me as well as others. For some of us only the instant release tablets work the best. The only way you find out is through trial and error.

That said it sounds like you need to go back to what you were taking before.

In addition please do the following and learn from my mistakes:

1) Track the different brand and generic forms of ritalin/methylphenidate to see what works best for you.

2) Use a daily journal to track your diet, dosages, and sleep habits

3) Definitely take the appropriate b vitamins and amino acid precursors to keep your dopamine and serotonin levels up and optimized. Such as L-tyrosine and L-tryptophan, b6, and a good multi B vitamin. All of what i am suggesting can be found in the mood cure and free book to download calles The way up from down as well as in Dr. Amen's book.

4) Do read Dr. Charles Parker and watch his videos. Do read Dr. Amen's Healing ADD. Do read the mood cure. If you are like me with low energy and Primarily Inattentive ADD and you take stimulants to increase motivation and improve daily functions you really need to keep your neurotransmitters optimized or you will crash hard like me someday.

My point is this. With the birth of the internet and all of the information out there you can do so much more to get and stay well. Provided you educate yourself as much as possible on the subject of nutrition and supplements for ADD and ADHD in addition to the different medications available.

I cannot stress enough the importance of knowing how food, supplements, allergies, and hormones effect how well you do with Ritalin and adderall.

Lastly, do try the other forms of stimulants such as adderall, dexedrine, evekeo, and whatever else so you can find the best medicine for you.

I stuck with Ritalin for years until I decided to try adderall which turned out to be much much better for me and made me into the person I always wanted to be.

You don't know what you don't know. So you have to try everything until you do know.

Here is a link I posted earlier about different forms of brand and generic Ritalin.

http://www.addforums.com/forums/showthread.php?t=187682

I am not trying to preach but if you are like me you need to be vigilant in knowing as much as you can to take care of that invaluable brain of yours, because low energy guys like you and me are much more sensitive to life's challenges than the high energy hyperactives. When we get knocked down it takes us longer to get up and recover.

Nutrition, protein, b vitamins, and neurotransmitter precursor such as nalt, tyrosine, 5htp, L-tryptophan, LPA, DLPA, and etc are key in avoiding tolerance and dopamine, norepinephrine, and serotonin deficits.

Prepare well for this journey because you will be on it the rest of your life.

All the best.

-M

Donker94
09-28-17, 05:27 AM
Donker94,

You sound very similar to me. So here are some suggestions and thoughts.

Yes, without question the extended version of any stimulant may work better or worse depending upon your metabolism.

None of the extended release products for Ritalin or adderall ever worked well for me as well as others. For some of us only the instant release tablets work the best. The only way you find out is through trial and error.

That said it sounds like you need to go back to what you were taking before.

In addition please do the following and learn from my mistakes:

1) Track the different brand and generic forms of ritalin/methylphenidate to see what works best for you.

2) Use a daily journal to track your diet, dosages, and sleep habits

3) Definitely take the appropriate b vitamins and amino acid precursors to keep your dopamine and serotonin levels up and optimized. Such as L-tyrosine and L-tryptophan, b6, and a good multi B vitamin. All of what i am suggesting can be found in the mood cure and free book to download calles The way up from down as well as in Dr. Amen's book.

4) Do read Dr. Charles Parker and watch his videos. Do read Dr. Amen's Healing ADD. Do read the mood cure. If you are like me with low energy and Primarily Inattentive ADD and you take stimulants to increase motivation and improve daily functions you really need to keep your neurotransmitters optimized or you will crash hard like me someday.

My point is this. With the birth of the internet and all of the information out there you can do so much more to get and stay well. Provided you educate yourself as much as possible on the subject of nutrition and supplements for ADD and ADHD in addition to the different medications available.

I cannot stress enough the importance of knowing how food, supplements, allergies, and hormones effect how well you do with Ritalin and adderall.

Lastly, do try the other forms of stimulants such as adderall, dexedrine, evekeo, and whatever else so you can find the best medicine for you.

I stuck with Ritalin for years until I decided to try adderall which turned out to be much much better for me and made me into the person I always wanted to be.

You don't know what you don't know. So you have to try everything until you do know.

Here is a link I posted earlier about different forms of brand and generic Ritalin.

http://www.addforums.com/forums/showthread.php?t=187682

I am not trying to preach but if you are like me you need to be vigilant in knowing as much as you can to take care of that invaluable brain of yours, because low energy guys like you and me are much more sensitive to life's challenges than the high energy hyperactives. When we get knocked down it takes us longer to get up and recover.

Nutrition, protein, b vitamins, and neurotransmitter precursor such as nalt, tyrosine, 5htp, L-tryptophan, LPA, DLPA, and etc are key in avoiding tolerance and dopamine, norepinephrine, and serotonin deficits.

Prepare well for this journey because you will be on it the rest of your life.

All the best.

-M

Thank you for this well written reply Achilles! I will definately continue researching on subjects that could affect my ADHD/ADD.
I'm taking Novartis(Both the instant and modified release) Haven't tried any others, but I might.
I track sleep aswell as food intake using MyFitnessPal.
"Do read Dr. Charles Parker and watch his videos. Do read Dr. Amen's Healing ADD. Do read the mood cure" Will do. Again, thank you.

I've read alot about Dex and Adderall, and as far as I know, Adderall is completely illegal where I live and you can't even get a special permit for it I believe. Dex on the other hand, I think it's possible to get a permit for, i'll look into it.

Here's a little info about my life before I was diagnosed with ADHD.

During my youth they basically thought I had depression, it all started when I was about 10 (I hit puberty early, acne at 10, facial hair started developing at 11), lack of motivation, didn't pay attention in school, didn't do homework, skipped school(worsened over the years). My parents divorced when I was 8. I started playing ALOT of video games, BUT I took up weight lifting at the age of 13 which has kept me in shape ever since, but even my workouts have been very on and off.
Never had any problems making new friends, in school I got along with pretty much everyone, always got invited to parties and other activities, but I prefered playing games honestly.
Dropped out of school at 17 cause I thought I was just tired of going to school and would rather enjoy working. 10 months is the longest i've managed to stick with a job, and that was during my cannabis period. Most my jobs lasted 1-3 months before I lost all interest and just quit.
I also "abused" cannabis from age 19-21, getting high first thing in the morning and kept it going until I went to bed. Completely stopped smoking when I got into a rough personal situation which resulted in extremely intense feelings and probably a cannabis induced psychosis. Luckily for me, I have many good friends and family who I trust, who helped me through it all. I do however (very rarely) get flashbacks from that period of time which makes me feel just like I did at the time, but it usually passes after minutes/few hours.
The only other drug i've done is coke, just once though, which I got through a good friend when I was out clubbing, only noticed an increase in focus and clarity of mind. It didn't make me more "WOO PARTY PARTY".
Alcohol has a tendency to make me extremely tired unless there's ALWAYS something happening and can also cause some depressive symptoms, so alcohol is not something i'm particularly fond of, which is good considering my father struggles with alcoholism(War veteran, PTSD). I still go out and drink with friends every now and then and I usually have a good time.
Was put on Zoloft after my little breakdown from the cannabis which literally didn't do anything. Doc upped the dose of Zoloft to 150mg and it still had no effect, which he thought was strange, we then we agreed that I could just stop using it.
I was sent to a sleep clinic to check if my sleep could be causing my problems. Turned out to be fine, a little snoring, but I was probably about 25-30% bodyfat so losing a little weight fixed that.
Multiple blood tests have been done which only shows that i'm healthy. Low test was something we looked into, but came back at 24ng/dl.
Resting heart rate was 49 bpm, blood pressure was 110/75, thyroid hormones were normal. so everything was implying that I was as healthy as a, well, healthy person!
After that, my doc finally decided to send me to a specialist and that's when I was diagnosed with ADHD(or ADD) and I finally got a spark of hope for a bright future.

I'm currently taking multis (I sometimes forget to take them however) called "Only one advanced+":

<table cellspacing="0" cellpadding="0" border="0"><tbody><tr><td>Astaxanthin</td><td style="text-align: right;"> 500</td><td> g</td><td> </td></tr><tr><td> Oli-Ola<sup>TM</sup></td><td style="text-align: right;"> 150</td><td> mg</td><td> </td></tr><tr><td> Beta-carotene</td><td style="text-align: right;"> 500</td><td> g</td><td> </td></tr><tr><td> Vitamin D3</td><td style="text-align: right;"> 10</td><td> g</td><td> 200%</td></tr><tr><td> Vitamin E</td><td style="text-align: right;"> 10</td><td> mg aTE</td><td> 83%</td></tr><tr><td> Vitamin C</td><td style="text-align: right;"> 200</td><td> mg</td><td> 250%</td></tr><tr><td> Thiamine (B1)</td><td style="text-align: right;"> 1,1</td><td> mg</td><td> 100%</td></tr><tr><td> Riboflavin (B2)</td><td style="text-align: right;"> 1,4</td><td> mg</td><td> 100%</td></tr><tr><td> Niacin (B3)</td><td style="text-align: right;"> 30</td><td> mg NE</td><td> 188%</td></tr><tr><td> Pantothenic acid (B5)</td><td style="text-align: right;"> 15</td><td> mg</td><td> 250%</td></tr><tr><td> Vitamin B6</td><td style="text-align: right;"> 1,3</td><td> mg</td><td> 93%</td></tr><tr><td> Biotin (B7)</td><td style="text-align: right;"> 100</td><td> <table cellspacing="0" cellpadding="0" border="0"><tbody><tr><td> g</td></tr></tbody></table> </td><td> 200%</td></tr><tr><td> Folic acid (B9)</td><td style="text-align: right;"> 200</td><td> <table cellspacing="0" cellpadding="0" border="0"><tbody><tr><td> g</td></tr></tbody></table> </td><td> 100%</td></tr><tr><td> Vitamin B12</td><td style="text-align: right;"> 9</td><td> <table cellspacing="0" cellpadding="0" border="0"><tbody><tr><td> g</td></tr></tbody></table> </td><td> 360%</td></tr><tr><td> </td><td style="text-align: right;"> </td><td> </td><td> </td></tr><tr><td> Magnesium</td><td style="text-align: right;"> 250</td><td> mg</td><td> 67%</td></tr><tr><td> Zinc</td><td style="text-align: right;"> 12</td><td> mg</td><td> 120%</td></tr><tr><td> Iron</td><td style="text-align: right;"> 10</td><td> mg</td><td> 71%</td></tr><tr><td> Manganese</td><td style="text-align: right;"> 2</td><td> mg</td><td> 100%</td></tr><tr><td> Copper</td><td style="text-align: right;"> 2</td><td> mg</td><td> 200%</td></tr><tr><td> Iodine</td><td style="text-align: right;"> 200</td><td> g</td><td> 133%</td></tr><tr><td> Chromium</td><td style="text-align: right;"> 125</td><td> <table cellspacing="0" cellpadding="0" border="0"><tbody><tr><td> g</td></tr></tbody></table> </td><td> 313%</td></tr><tr><td> Selenium</td><td style="text-align: right;"> 50</td><td> <table cellspacing="0" cellpadding="0" border="0"><tbody><tr><td> g</td></tr></tbody></table> </td><td> 91%</td></tr></tbody></table>

Donker94
09-29-17, 10:41 AM
Upped the dose to 50mg yesterday, very different from 30mg. after about 40-60 minutes I almost felt "high", a strong feeling of well being. i read some articles about ADHD and School, and it all felt so smooth. I'm used to having to read through something 5+ times in order to get a slight understanding of what the f*** i'm even reading.
A+ on that part, very similar to the effect I got from 10mg IR.

HOWEVER, after about 3-5 hours the effect start to fade. I become lethargic, drowsy etc.
I was told by my doc that the effects of this type of Ritalin should remain active for 12 hours. I feel like it's 1/3 of that.
I've also lost 9kg since I started the meds so perhaps the Ritalin has a strong effect on my metabolism which kinda makes sense. I also take the meds on an empty stomach and I was advised to do so. Maybe try and eat something first?