I am wondering why when I drink orange juice with adderall the effects and side effects are greatly INCREASED instead of being decreased. I know that is not what should be happening but it is not my imagination, there is a definite difference between orange juice and just using water. It will give me the side effects which addicts chase and that worries me a bit. I just don't drink orange juice any more ... I miss it, lol.

Afterthought: Could it be that the OJ is decreasing the amount that is absorbed into my urinary tract and could mean that I just need a smaller dose in the first place, for adderall to be most effective?

Are you sure you're drinking Orange Juice, and not Grapefruit Juice? Grapefruit juice has been known to inhibit certain liver enzymes, and thus make some drugs more effective. Other than that, I don't know how OJ could be causing your problems. One of the few things I hate about Adderall was having to give up my orange juice, I used to drink the stuff like crazy, it's sooo good.

Any literate person should know what they're drinking, I suspect he's drinking orange juice. Very odd effect indeed. I can't offer any explanation.

I always take my medication on a somewhat empty stomach with water, and wait 15 minutes before eating at least.

I am confused, are add/adhd people literate? It could be the sugar in the orange juice is getting him alitte higher than when he doesn't take his adderall with orange juice. Some medication you gotta take on a full stomach or the med will eat the lining to your stomach. :)

Orange juice has citric acid which "voids" out the effectiveness of amphetamines.

Try not eat or drink anything containing citric acid or Vitamin C for at least 2 hours after your Adderall dose. Otherwise, you may as well take that Adderall tablet and throw it in the garbage, 'cos it won't work.

There are anecdotes showing that orange juice may not necessarily have that effect. Still I would avoid large amounts of it within at least 30 minutes of ingestion of your medication.

Vitamin C, unless you're megadosing, say multiple-grams of ascorbic acid, might not be detrimental. Calcium ascorbate in particular might be a safe form. And it's a question of degrees, not black and white.

I have also heard some reports that acidic drinks may not cause many problems for the simple fact that it is the pH level of the intestines, not the stomach, that determines the absorbtion of amphetamines. So while drinking lots of orange juice would acidify the stomach, it might not necessarily have much effect in the intestines. On the other hand, I know from personal experience that antacids definitely increase Adderall absorbtion, so who knows

Is this intense effect lasting as long as normal? I know my liver processes stuff strangely, maybe the OJ is somehow is concentrating the dose and jamming it through all at once thus the intensity of the side effects?
Am I making sense?

I think I sort of understand what you are saying, but no, I would doubt it. With some drugs, you would be correct, an acidifying agent will increase absorbtion and speed it into your bloods stream, which is just a scientific way of restating your "concentrating the dose and jamming it through all at once." Unfortunately, this is not the case with amphetamines, and they actually absorb less in acidic environments.

The basic reason for this, from what I understand, is that the amphetamines will not be absorbed by the intestines until they are first converted from their salt form into an ionized, or charged, freebase form. This is why making Adderall with different salts gives it a varying absorbtion rate, because it takes different amounts of time to separate amphetamine base from its sulfate salt vs. its aspartate salt vs. its saccharate salt. Anyways, the general theory has been that drinking something acidic, like OJ, results in any free amphetamine being converted into amphetamine citrate, which then means that less will be absorbed. If the OJ were doing anything special, it would be this, which would not give the results that you are reporting.

It is possible that the OJ helps break down other foods present in your stomach, and this gets everything, including the Adderall, out of your stomach and into your intestines for absorbtion faster, and that in this hypothesis, the OJ doesn't make any serious change in your intestinal pH, which is usually higher (less acidic) than your stomach anyways.

Incidentally, lest anyone think that swallowing freebase amphetamine would absorb faster for the reasons described above, this is equally unlikely. I would assume that if swallowed, amphetamine freebase would be converted in the stomach into amphetamine hydrochloride, just as any other swallowed base would be.

Sorry I have been gone for a few days, but thanks for the input! Well I read the posts and I drank some OJ again, just to make sure it wasn't in my head. It definately is way to intense to be helping the situation. I go into clean everything I see mode and start going wild, wasn't a good thing. I do not know if this would be any help but I am EXTREAMLY sensitive to what I put in my body or anything thing in my envrioment. I have ran into drugs a year ago and the smallest amount just took ahold of me. The same amount in a lighter person would do absolutly nothing, at all. Might that be because of the way I absorb things? BTW I have a problem with digesting things, so much so that I have to go see the doctor about it because for a while now I keep throwing up after I eat. When I do, not to be disgusting, but it is barely digested even after three hours ... I don't know maybe this could be part of the problem?

BTW I have a problem with digesting things, so much so that I have to go see the doctor about it because for a while now I keep throwing up after I eat. When I do, not to be disgusting, but it is barely digested even after three hours ... I don't know maybe this could be part of the problem?
This does help explain things. By helping break things down in your stomach, it's probably speeding the absorbtion. Prune juice can help as well, as would metamucil or other fiber supplement.

OJ shouldn't make any noticable difference. The acidic effect is going to be very weak, at the most, and it's grapefruit juice that interacts with medication - and the chemical that does this is specific to grapefruit. Also, even if you did drink grapefruit, stimulants aren't metabolized by the same enzyme, so grapefruit wouldn't make a difference either.
I'm concerned about the throwing up - I suspect that something else is going on, rather than OJ. Please see your doctor about it!

man this ish has been happening with me too.

MAKE IT STOP~!!!

There is a warning you should get from the pharmacy saying the following...*seriously, it's bull! who DOESNT drink fruit juice??!?!?*


Rite Aid Pharmacy for Adderall XR 30mg:

"Certain foods and drugs can affect the amount of acid in your stomach/intestine and increase or decrease the amount of absorption of this medication. Tell your doctor if you take any of the following products: fruit juice, ascorbic acid (vitamin C)..."

oh my gosh. thank you so much for that information. now i have something to show my parents so they believe me.

but what else can i take?

does concerta or ritalin have these warnings?

Hm I have no idea...this is my first scrip of ADD meds so I was just leafing thru and noticed that...I haven't seen the prescription information for Ritalin or Concerta.

hopefully it's not there. i'll check the website and repost.

no, there's nothing there on the important product information page. :)