On Monday I started taking FocalinXR (10 mg) and Zoloft (25 mg). I really didn't feel much of anything other than a slight headache and some jitters. I talked to my doctor and she said to increase the focalin to 20 mg and give it a week. I did that for the first time today and WHOA! No headache or jitters, but I feel like I have a bad head cold without the stuffiness, like I'm drunk or something. Very off-balance. Is this a normal reaction that will go away with time? Focusing is good, but I'm just not sure about the physical feelings.