View Full Version : A Desoxyn comeback


MillenniumMan
11-20-05, 08:50 PM
guess what I heard Desoxyn is coming back.

in 5 MG and maybe 10 MG...isn't Dexedrine only 5 MG's???

netsavy006
11-21-05, 11:44 AM
I've never heard of Desoxyn, but I've heard of Dexedrine. My brother was on it, but it made him worse.

Hyperion
11-21-05, 03:44 PM
Desoxyn is very rare. I know that it is still prescribed, but only for very certain cases, it's really more of a last resort, when Dexedrine is working but not well enough.

MillenniumMan
11-23-05, 11:05 PM
You said Desoxyn is very rare...why is that???

why is it a last resort???...

saskman
11-23-05, 11:14 PM
Desoxyn is pharmaceutical methamphetamine. try asking your doc for a prescription of that! :)

UnleashTheHound
11-23-05, 11:32 PM
You said Desoxyn is very rare...why is that???

why is it a last resort???...
Because people hear that it is methamphetamine, and it raises all sorts of red flags. Nobody's proven that Desoxyn taken as prescribed is any more dangerous than Adderall or Dexadrine, but the name scares people.

MillenniumMan
11-24-05, 07:19 PM
thanks for letting me know.

Frangible
11-28-05, 02:09 PM
Another problem with it is the long plasma half-life (8 hrs to amphetamine's 4), which can cause long term sleep deprivation even at a theraputic dosage. Of course, the main factor is the meth witch hunt makes it politically incorrect.

katatak
12-01-05, 06:50 AM
Another problem with it is the long plasma half-life (8 hrs to amphetamine's 4), which can cause long term sleep deprivation even at a theraputic dosage. Of course, the main factor is the meth witch hunt makes it politically incorrect.It seems to me that it dose what Dexedrine Spansules claim to do but much better. You would think that it would be a natural as a real long acting medication. Witch hunt indeed! ... we are the collateral damage!

Katatak

Hyperion
12-03-05, 10:40 PM
The other issue is that it is more potent on a weight by weight basis. This means that one has to use lower dosages, which is not in and of itself dangerous, but it does make changing the dose a little more difficult because small changes can have larger effects.

Also, since Adderall and Dexedrine are useful for most people, there isn't a huge need for it aside from people who find that either of the other drugs aren't effective, or for people who need larger doses of the other drugs, where switching to Desoxyn could provide the same central stimulation without risking massive peripheral stimulation. For an idea of the difference between central and peripheral stimulation, think of the difference between amphetamine and caffeine.

But yeah, I wouldn't be surprised if politics plays a bit into it as well, with methamphetamine having a level of stigma that other amphetamines don't. After all, morphine and heroin are related to each other in the same manner as amphetamine to methamphetamine. Yet they have very different legal statuses in the US that are due entirely to perceived stigma, whereas both are used to medicinally to treat pain in the UK.

Dogg
01-02-06, 12:51 AM
From what I have read Adderall has more peripheral stimulation than Desoyn. Why would you want that?

attention
01-07-06, 04:48 AM
Dexedrine actions:

- psychostimulant:
NE release +++
DA release ++
DA reuptake inhibition +
NE reuptake inhibition +

Desoxyn (Methyamphetamine Hcl) action-note the 5ht (Serotonin) difference:

- psychostimulant:
5-HT release +++
NE release +++
DA release ++
DA reuptake inhibition
NE reuptake inhibition

Desoxyn is effective at lower doses and is longer lasting than Dex. Abbort used to manufacture a 15mg SR tablet which held for 12 hours, but all that is available now (since 2000) is Ovation Pharms 5mg IR tabs, which are less effective and give a quicker, shorter effect, than Abborts excellent Desoxyn, which came in:
-5mg IR
-5mg SR "Gradumet"
-10mg SR "Gradumet"
-15mg SR "Gradumet"

Because of the Gov'ts war on Meth, Abbort sold Desoxyn to Ovation, who dropped the SR and reformulated the IR 5mg tabs, (all that is available now) so that they dissolve in 5 mins as opposed to 15 mins for Abborts.

Desoxyn is usually a last line resort treatment if a patient has had unsatisfactory response to higher doses of the other stims, even then MOST PsyDocs are loath to script Desoxyn-because of its notorious compound name (Methamphetamine), despite the fact that Desoxyn has THE lowest peripheral stimulation, compared to CNS action. It is often very effective for folks who have a tolerance to stimulants.

Contrary to belief, long term medical Methamphetamine usage doesn't turn someone (who has a medical need for it) into a burnt out 'speed freak'.
I have an aquantaince in his 60's who has sever Narcolepsy and has taken Abborts Desoxyn 4-5 15mg 'Gradumets' 60-75mgs daily, for 40+ years to stay awake during the day-and says that kept him functioning "almost like a normal person". He now takes 4-5mgs Desoxyn 4x day=80mgs daily, (with 600mgs Provigal) with less effective results that the Abborts SR Desoxyn, Ritalin 60-80mgs wasn't very satisfactory, neither was Dexedrine+Parnate.


Desoxyn when used under medical supervision, is often the BEST treatment for difficult to treat cases of ADD/HD, with few SE's to boot.