Anyone tried this combo? I am taking Wellbutrin XL 150mg and Lexapro 5mg. Both help with depression/anxiety. About to add Adderall 10 mg to the mix for desperately needed help with focus.

This is my first real attempt to medicate for ADD, although it has pretty severly f***ed up my life (two divorces, etc.)

Let me know if you have tried these three meds in combo and if it helped you.

umm... all i can say is good luck with that one... adderall made my anxiety worse! and my paranoia but after that i tried dexedrine and i love my dexedrine's (the brand, i filled my Rx for brand and only got about 20 pills outta my 120 script... yikes!, so i hadda get the rest fileld with barr, YIKES!!! caint wait for brand to get back in buisness) anyway good luck you might wanan start out with brand then go to generic as brand usually is alot better with side effects (i think its in the way its made (metal or titanium container, plastic bottles for storage or alluminum or maybe its just the chemical purity or grade of the chemiclal) anywy sry for rambling on i gotta do some other stuff good luck

PS NEVER tried that combo but i have been on welbutrin and adderall not the anxiety stuff

I'm on Wellbutrin and Adderall and it works great for me. I take Neurontin occasionally for anxiety (and Xanax once in a great while for flying and the dentist). I have not taken Lexapro with it- I took Celexa alone several years ago and it did not work at all for me- but I have not found myself being any more paranoid on these meds (with the exception of the first couple of weeks on Wellbutrin). I have found that they do make me far more sensitive to caffeine, though, which can make me feel very speedy and anxious, so you might want to cut down or skip coffee/soda while you start.

I hope it works for you!

I've been on Lexapro for 3 years, taking 20mg and just started 3 weeks ago on Adderall XR 10mg. It's working well for me, my doctor said there's no conflict between the 2 drugs. One's for depression, the other to improve focusing, which I desperately need.

Wellbutrin is a good supplemental anti depressant, its kind of weak sauce on its own but when combined with another med it can have interesting effects.

But wellbutrin essentially does the same thing as adderall, They both blockade norepinephrine and dopamine receptors causing you to have a larger amount of these neurotransmitters in your brain. Of course adderall is much more efficent at the dopamine reuptake inhibiting...im not sure how they compare norepinephrine wise.

I've been on Lexapro 10mg for a few years now and it's helped me combat a lot of my anxiety. I also take 20mg of Adderall.

Hi i am doing that combo now ..150 mg of wellbutrin for depression and 30 mg of adderall extended form. It works good so far.

I am taking Lexapro and Adderall for a few months now....seems to be a good combo...

I was considering the wellbutrin for supplimental energy/lack of sex drive. I really hate both those side effects, and although I love the focus of adderall I dont like how I am almost sedated (I have inattentive add). do you think this is too much, I do not suffer from depression, only anxiety, so more pills could be a bad idea.

Wellbutrin is a good supplemental anti depressant, its kind of weak sauce on its own but when combined with another med it can have interesting effects.

I respectfully disagree. WB alone is pretty strong sause for me. Adding an SSRI to it did not play nice with my brain, nor did an SSRI alone.

Is anyone taking all three?

will-

so you are saying you feel heavy sedation with the lexapro added in with your adderall correct? In general there are some success stories with ssri's and more with effexor but for the most part it doesn't play well unless it is effexor for some odd reason. I'd say wellbutrin and adderall is a common adjunct but you just don't see too many on all 3 although I could be wrong. I've been contemplating this as well because I take wellbutrin normally with mph or concerta and from time to time I will switch to adderall and wellbutrin and I've been told my personality could use some softening and I agree but honestly it's alot of times not worth the mental slip when you add an ssri especially one like lexapro ( very selective) but it will make you happy no doubt. I would guess effexor is an option . Good luck

Yeahh definitely heavy sedation....I didnt take any stimulants now and I'm at work trying to stay away (I have been funnelling coffee all morning).

For this reason, and the sexual side effects, I think I need to come off Lexapro, since finding energy has allways been a constant struggle for me allready.

I am worried about effexor because of all the horror stories...but I hear it can be a good treatment for adhd...I am also thinking that I might just stick to stimulants alone, since the SSRI my be the culprit for my lack of energy.

I just started taking WB 100mb x2 and I'm only on my 2nd pill and I am not liking the tweak it's giving the brain. I'm stressed a little right now and the WB seems to add to the tweak. So, so far it's not a good thing.....:(

i take almost the same thing. i take wellbutrin sr (250mg per day in two doses), 20mg adderall xr and 50mg zoloft. zoloft is almost the same as lexapro... they are both SSRI antidepressants. this combo is working really well for me. the zoloft actually makes my adhd worse, as SSRIs tend to do but i need it for depression and anxiety treatment. it works well enough to allow me to take adderall. i don't get anxiety from adderall at all. the wellbutrin is a nice add-on for adhd treatment. it would never replace a stimulant like adderall but i feel the combo is better than each alone. is there anything more specific you wanted to know?

i honestly think that you would have or I have read about more success stories with stimulants and effexor , pristiq or cymbalta than the traditional or more selective ssri's

Indy...I was thinking that combo would work really well. Dont know if my doc would be down with that either, since I am combating anxiety/add/ocd not really the depression...

But in theory, the wellbutrin would combat my constant lack of energy, adderall/ritalin for focus, and ssri for anxiety/ocd...Right?

I just think that might is too much tweeking...and I am still in college so I do my fair share of partying (dont want to be drinking on 2 anti-dep)....my ocd of finding the "perfect combination" coming in to play...

serotonin reuptake inhibitors and amphetamine can cause the fatal serotonin syndrome. check out some threads in this forum and dexedrine regaurding serotonin syndrome and talk to the doc/pharm, its a serious thing

yeahh read about that sounds miserable....is that an issue with ritalin/concerta

No, it seems not to be related in anyway because those meds have no effect on serotonin at all. amphetamine is actually quite potent at serotonin release, so thats where the problem lies.

Only issue i can see from wellbutrin+ritalin is something like a seizure, but i mean thats less of a problem if you dont have a seizure risk. Those two meds tend to lower seizure thresholds, so as long as your not prone to that, it wouldnt be an issue (and your dose of wellbutrin and adderall arent high, as well), doesnt hurt to ask the doc tho about your personal seizure risk.

I dont have brain damage or epilespy, but personally i seize sometimes during sleep cycle shift, so I stay away from seizure threshold droppin meds

yellow,

what do you feel about focalin xr, wellbutrin and adding small dose of cymbalta or lex at night to help with ruminating ?

hello hollywood, hope youve been well.

I think the cymbalta is unnecesary. SNRI (cymbalta) + NDRI (wellbutrin ) = too much NRI as is, but then throwing in focalin, which while it is more geared toward DA than NE in comparison to ritalin, its still another NDRI, its just overkill for norepinpehrine reuptake. Id imagine it would be quite uncomfortable and anxiogenic, which I know you wouldnt want. your triple boosting NE through 3 different drugs in that way

Lexapro (a pure SSRI without any NDRI at all), Wellbutrin (NDRI), and Focalin (DNRI) would be pretty good though = single boost of SE + double of DA + doublish of NE.

If you recall, though, the reason i thought zoloft was the best of the reuptake inhibitor AD's is because it combines SSRI + DRI without any NRI goin on, so maybe high dose of zoloft and focalin would be what your looking for: single boost of SE (zoloft) + double boost of DA (zoloft + focalin ) + minimally slight boost of NE (focalin), or if you wanna try throwin in wellbutrin, you get a triple DA and double Ne boost...

and also, zoloft is especially useful for broadspectrum depression+anxiety so maybe its still on option to reconsider if ur still considering cymbalta

yellow ,

I was allergic to zoloft , I got hives all over my body , it's the only med that I have ever had this happen with. I hear lexapro is really sedating , if it weren't I would think it would be a good addition

I take 20 mg/day of Lexapro (called Cipralex here in Canada). It has done a very good job of pulling me up from depression and killing off anxiety. In other words, it has kept me from feeling too bad. On the other hand, it has also blunted emotions the other way... I haven't felt "good", whatever that means.

About 10 days ago, my doctor added Wellbutrin XL (150 mg/day) to the mix. After 4 or 5 days of feeling nothing but a few annoying side effects, I suddenly started to feel "good". It is a little easier to focus on what I choose, I feel like I have mental energy, and I actually seem to enjoy my life. All of a sudden, I can do daily chores without having to psych myself up or feeling resentful afterwards. I signed up for a martial arts course that I've been considering for over a year (without acting on), and really enjoyed the first session.

The best part... my 11-year old daughter said this to me on Saturday... "What's wrong with you? You seem happy!"

bill,

so you think lex is good?

Hollywood... I think the lex did an excellent job of killing off my depression and anxiety. On the downside, it seems to blunt all my emotions, even the good ones. Plus, it seems to make me feel sluggish, but that's still a lot better than how I felt in my depressed, anxious state.

The Wellbutrin my doc added recently has done a good job of addressing the negative effects mentioned above. It's still a little early yet (about 2 weeks), but the combination of Cipralex / Lexapro and Wellbutrin seems to be a good one for me right now.

Yeah I completely agree with that...unfortunately, for me it seems to somewhat level out the big highs and lows...if that makes sense. I went to 5mg and haven't really noticed a difference.

I do think that it helps with the side effects of the stimulants, especially when they wear off.

since april I've been trying to complete my whole adhd puzzle. It's the hyperfocus thing at work which really gets to me , If I could just level out just a tad... Its between pristiq, lex, or cymbalta in a tiny dose. I have just yet to stick with one for long enough. Does anybody have any hands down advice as to which one would be best for hyperfocus, some anxiety and may help adhd a bit like for social shyness? I think pristiq may help .. Not sure it's between those three

Hollywood...I have been on Cymbalta for about a year now! I love the drug, it really helps with depression. I have noticed that things that would really depress me now don't bother me. It is a powerfull drug so don't jump on and off as you say you are, give it time to work and stay with it. However, you may or may not have experienced an unnerving sexual side effect to Cymbalta. I won't give all the details here but if you are experiencing any sexual side effects and want to discuss them, then send me a note.

Ok, I've been on Wellbutrin in the past and it made my anxiety pretty bad. When I tried Adderall while on Wellbutrin, I had anxiety attacks for the first time in my life. My totally stopped Adderall after about 1 week into it and my Dr. stopped my Wellbutrin and switched me to Lexapro and Vyvanse. This combination has been perfect with me.
Now Vyvanse has a tendency to wear off a little too early and we're retrying the Lexapro with Adderall. I haven't started yet, but I'm extremely nervous. I've got little children who I stay at home with all day and am so afraid that the Adderall will cause panic attacks again. We'll see how it goes though.