View Full Version : Adderall and Citric acid
Flitter 08-30-06, 12:51 PM I'm still trying to figure out this citric acid rstrictiong the absorbtion of Aderall thing..
Now does any one know if this is ALL fruits including stuff like Tomatoes?
I mean if I have some pasta with marinara or even some pizza, will the tomatoes in the sauce reduce the absorbtion of Aderall? I know that XR is slowly released so I imagine it would be an all day thing..
How about a multi vitamin that has vitamin c in it?
Am I doomed to a life of choosing the effects of Adderall over ever eating fruits again?
That would suck
Thanks... flit
Honda Shadow 08-30-06, 02:58 PM I have just been put on adderall and I am Italian. I hope tomatoes dont' effect it. I have noticed that if I eat sugar it makes me feel terrible.
Would some of you know if sugar is a no no? I am about 30 lbs over my weight need to lose it. With depressions which also means boredom to me comes eating. So far with adderall I have been able to control this. Thank god. I know alot of us suffer from the pound syndrome.
lovemytiel 08-30-06, 11:39 PM I still drink my fruit juice every morning..right after I take my adderall. I think I am fine. I have to get my nutrition in sometime...and I dont really notice it doing anything to my adderall.
WebMD said pretty much the same thing as below...
I haven't changed my eating habits much and I eat fruit and tomatoes all the time.
I want to say that I never felt an impact - but... I'll have to pay attention to this.
And I take Tums sometimes... My highlights in red.
Maybe this contributes to some people requiring higher doses.
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601234.html#special-dietary
<H4>What special precautions should I follow?Return to top (http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601234.html#skip)
Before taking dextroamphetamine and amphetamine,
tell your doctor and pharmacist if you are allergic to amphetamine, dextroamphetamine, any other medications,or corn.
do not take dextroamphetamine and amphetamine if you are taking monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl), and tranylcypromine (Parnate), or have stopped taking them within the past 2 weeks. If you stop taking dextroamphetamine and amphetamine, you should wait at least 2 weeks before you start to take an MAO inhibitor.
tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and herbal products you are taking. Be sure to mention any of the following: alpha blockers such as alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), tamsulosin (Flomax), and terazosin (Hytrin); antacids; antidepressants ('mood elevators'), antihistamines; ascorbic acid (Vitamin C); beta blockers such as atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal); chlorpromazine (Thorazine); diuretics ('water pills') such as acetazolamide (Diamox); guanethidine (Ismelin); haloperidol (Haldol); lithium (Lithobid, Eskalith); medications for high blood pressure; medications for seizures such as ethosuximide (Zarontin), phenobarbital (Luminal, Solfoton), and phenytoin (Dilantin); meperidine (Demerol); methenamine (Hiprex, Urex); propoxyphene (Darvon, Darvon-N,); reserpine (Serpalan); sodium bicarbonate (Arm and Hammer Baking Soda, Soda Mint); and sodium phosphate. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
tell your doctor what nutritional supplements you are taking, especially glutamic acid (L-glutamine).
tell your doctor if you or anyone in your family has or has ever had motor (repeated twitching of any parts of your body) or verbal tics (repeating of words or sounds) or Tourette's syndrome (difficult to control need to perform repeated motions or to repeat sounds or words). Also tell your doctor if you have or have ever had an glaucoma (an eye disease); depression; anxiety, tension or agitation; mental illness; or thyroid disease.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking dextroamphetamine and amphetamine, call your doctor. You should not breastfeed while you are taking this medication.
you should know that this drug may make it difficult for you to perform activities that require alertness or physical coordination . Do not drive a car or operate machinery until you know how this drug affects you.
you should know that dextroamphetamine and amphetamine should be used as part of a total treatment program for ADHD, which may include counseling and special education. Make sure to follow all of your doctor's and/or therapist's instructions.
What special dietary instructions should I follow?Return to top (http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601234.html#skip)
Talk to your doctor about drinking fruit juice while taking this medicine.
</H4>
I'd worry more about 'diuretics', than citric acid.
Adderall causes me to dehydrate enough, by itself.
I woudn't think taking diuretics, on top of it, would be a grand idea.
I am a biochemistry student, montioning this to let you know that while I'm not an expert I do know what I'm talking about, also metionning this because I have self-confidence issues as we all know accompanies this. I was just diagnosed 2 months ago and started taking adderall two weeks ago. Everything was great until one morning I ate a Power Bar Protein Plus. I ate 2 5mg adderall tabs with it. An hour and a half later I had indigestion and no effect from the adderall. Took another two pills over the next 2 hours, that's 20mg over 3.5 hours. I should have been super-hyper foceused to the point of feeling raggedy from the stim. Yet there were none of the usual signs. So later after my last class I drank a cup of coffee and took 2 more adderall. Then it finally kicked in. I got to thinking about amphetamines and their chemical properties. Did a little research and with my knowledge concluded this (this should by no means be supplanted for any official medical advice)
Adderall is an amphetamine. Amphetamine is a base in the chemical sense. When they say that the amphetamine is supplied as a salt, the mean that the "basicness" of the molecule has been neutralized with either sodium, or potassium or some similar substance. Why? When the salt goes into your stomach the metal atom leaves the molecule leaving the base behind. Amphetamine are transferred to your brain by a lipid(fat) mechanism involving a tranfers protein. In order for the amphetamine to get attached to a protein and transferred through the lipid mechanism it needs to stay a base. When your stomach is really acidic whether from something you ate, or in my case indigestion, the amphetamine gets neutralized, and becomes water soluble and can't bind to the protein which is required to transport the amphet to your brain. When it is neutralized it is not absorbed very readily and I believe although I'm not sure that the amphet. may just wash out of your body or get tied up in some other process and excreted as feces or urine(not to put those images in your mind). That is why there are warnings about vitamin c(lowers uptake) and tums(increases uptake). I have become very mindful about the state of my stomach. Drinking decaf coffee will help you absorb the amphets. drinking o.j. will not. Something to remember for those uncertain about whether or not the food or drink is acidic or basic, acid=sour base=bitter(in a very general sense).
Hope this helps, any?'s feel free to shoot me an e-mail. I'll answer to the best of my ability.
steviefranchise 09-27-07, 07:19 AM Very imformative RABN.
Read this and let me know what you think. It is a quote from Robert Young, Alkaline diet advocate.
It is often said that "acidic" fruits like lemons, limes and low sugar grapefruits are acidic and will acidify the fluids of the body. In fact, the citric, lactic, and other acids in such fruits exist primarily in their anionic form, especially as their Na+ and K+ salts (e.g., potassium citrate or calcium ascorbate).
Following absorption, these anions are metabolized to bicarbonate (HCO3) and therefore will alkalize -- not acidify -- the blood and tissues. Alkalinization occurs even though the fruits pH in vitro is typically low (4 pH), because the free protons are more than offset by the generate bicarbonate -- electrons. For example, a liter of diluted lemon juice (1 part lemon to 10 parts distilled water) with a pH of 4 has only 0.1 mmol (i.e., 10 to the minus 4 moles) of free protons. As long as the quality of organic anions exceeds this small number, which it does, a net alkalinization will occur.
I hope this gives many of you clarity concerning the alkalinization of low sugar fruits in vivo.
tomxkite 01-07-08, 03:40 AM I have found that the adderall+caffine make a great combination for me. Most people suggest not combining these two, but since I have found them to work well, I am reluctant in letting them go.
It is not uncommon for me to have diet Pepsi Max ( 70mg caffine per 12 oz can) about the same time as I have Adderall, or have some cappuccino from Starbucks (100mg caffeine) at the same time.
Coffee might interfere with the absorption of adderall but it does add a kick due to caffine. So as long as I am getting desired effect, I am OK with it.
I guess the key is to keep it consistent.
I have ton of issues to deal with (that's why I am taking Adderall to begin with); I am not sure I want to add stringent diet restriction to it.
So if orange juice reduces the absorption of Adderall, and if you take 20mg Adderall, then may be the right dosage for you is either 20mg Adderall and no fruit juice and no soda; or 25mg with moderate amount of fruit juice and soda, as long as you do it consistently.
Your millage may vary.
Hello to everybody from Germany. Lucky you that are able to get Adderall, here in Germany there is no Adderall but the pharmacy has to mix Amphetamie capules by themself.
The self produces amphetamine capsules contains:
amphetamine sulfate 0,020
acid citric 0,020
and saccharum lact and aerosil.
Therefore I was googling about the possible interaction of amphetamine and the other stuffs in this capsule.
Can any of you adderall users tell me what is in the adderall capules according to the package leaflet besides amphetamine? Is there also acid citric in?
I am concerned of a possible unwanted interaction because I read this: http://health.yahoo.com/urinary-medications/citric-acid-and-sodium-citrate/healthwise--d03952a1.html
It is written:
"What other drugs will affect citric acid and sodium citrate?
Before taking citric acid and sodium citrate, tell your doctor if you are taking:
amphetamine and dextroamphetamine (Adderall)"
I can't believe after all the research I've done on Adderall and for how long I've taken it I've been drinking tons of OJ this whole time!!! Oh Snap!
HighFunctioning 01-11-08, 10:30 PM The citric acid content probably isn't high enough to make a difference. Adderall capsules (only XR comes in a capsule) contain triethyl citrate, which I believe is a form/derivative of citric acid.
The citric acid content probably isn't high enough to make a difference. Adderall capsules (only XR comes in a capsule) contain triethyl citrate, which I believe is a form/derivative of citric acid.
Well I take the regular 20 mg tablets and usually follow that with 16 ounces of OJ. hmmmmm... I think I'll just start drinking it at night instead.
edited to add: I just realized you probably weren't even talking to me in your post! sorry.
HighFunctioning 01-12-08, 12:15 PM My citric acid comment was directed towards Cetin's post (as to how some locally created capsules seem to contain citric acid).
(Edit: I just realized that you realized, it would help if I read posts outside of my email-box)....
The problem with OJ is that it also contains Vitamin C.
My citric acid comment was directed towards Cetin's post (as to how some locally created capsules seem to contain citric acid).
(Edit: I just realized that you realized, it would help if I read posts outside of my email-box)....
The problem with OJ is that it also contains Vitamin C.
Thank you, so I do not have to worry about the capsules mixture made by my pharmacy guy containing citric acid because the amount is just too small to have an effect. That sounds easing to me as I thought he may have done a mistake by using citric acid in the mixture. And it eases me also to hear that even Adderall contains acid (triethyl citrate) so it cannot be that wrong.
By the way, what do you pay for Adderall or Dexedrine? I had to pay 108,50 Euro (about 150 US-Dollars) for 120 capules. I have to take 2 capsules, so that costs me 75 Dollar every month.
The citric acid content probably isn't high enough to make a difference. Adderall capsules (only XR comes in a capsule) contain triethyl citrate, which I believe is a form/derivative of citric acid.
acetic acid pka 5
citric acid pKa1=3.15
pKa2=4.77
pKa3=6.40
water pka 15.7
methyl acetate pka 25
An ester like triethyl citrate is not very acidic.
I found this link that talks about Adderall.
http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=5535
acetic acid pka 5
citric acid pKa1=3.15
pKa2=4.77
pKa3=6.40
water pka 15.7
methyl acetate pka 25
An ester like triethyl citrate is not very acidic.
I found this link that talks about Adderall.
http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=5535
Thank you for the informative link above.
Can anybody tell me how long Amphetamine can be stored without losing its effectiveness or is there no date of expiry? Is there a "Best-Before" Date written on Adderalls package?
VerySadKnicksFan 01-18-08, 01:09 PM Pop some Tums, they help. Plus they have calcium, which is something my body needs anyway!
Pop some Tums, they help. Plus they have calcium, which is something my body needs anyway!
I would like to, but I do not know what "Tums" are. My dictionary does not tell me about it. Sorry for not being a native english speaker. Can you please describe "Tums"?
Can anybody tell me how long Amphetamine can be stored without losing its effectiveness or is there no date of expiry? Is there a "Best-Before" Date written on Adderalls package?
Away from light in a tightly sealed (air tight glass jar) at room temperture or lower for likely alot longer than the offical expire date.
I would like to, but I do not know what "Tums" are. My dictionary does not tell me about it. Sorry for not being a native english speaker. Can you please describe "Tums"?
Calcium Carbonate, CaCO3 with some flavors and sugars added.
http://www.chemcases.com/pheno/pheno16.htm
URINARY ALKALINIZERS: Citric Acid (!)
Wow, that is strange! It says that an acid works as an alkalinizer! Well, maybe I should drink also orange juice?
http://www.chemcases.com/pheno/pheno16.htm
URINARY ALKALINIZERS: Citric Acid (!)
Wow, that is strange! It says that an acid works as an alkalinizer! Well, maybe I should drink also orange juice?
Salts of weak acids and strong bases are basic. So supposable citric acid metabolizes to basic.
That would decrease excretion of amphetamines in your urine. But citric acid
interferes with absorption of amphetamines to.
Scattered 01-27-08, 06:27 PM Thank you for the informative link above.
Can anybody tell me how long Amphetamine can be stored without losing its effectiveness or is there no date of expiry? Is there a "Best-Before" Date written on Adderalls package?My medication has an expiration date written on it -- I expect that equates to a "best-before" date.
My medication has an expiration date written on it -- I expect that equates to a "best-before" date.
Won't you tell me how long Adderall is storable? When did you bought your Adderall and what expiration date is written on it?
Hutch1ns 01-28-08, 08:02 AM Won't you tell me how long Adderall is storable? When did you bought your Adderall and what expiration date is written on it?
Adderall doesn't go bad, but it will lose it's effectiveness over time. All prescription bottles in the US will say 365 days following the date the prescription was filled. I'm not sure how long it really takes before it starts to lose it's effectiveness.
--reposting this here - at first i thought it too long winded for a reply, but this is after all the thread that inspired me so here ya go! ADHD at it's best --
Greetings,
First of all, I'd like to express my gratitude for all the information and serenity I've found in just a single thread on this forum
(Adderall and Citric acid). http://www.addforums.com/forums/showthread.php?p=538731#post538731
I got here from Google by doing a search on the combined effects of Adderall and Vitamin C.
I was diagnosed as a small child; I'd guess around 5 or 6 years of age. My mother did not believe in medicinal treatment for ADHD so I was never given any until recently. I am now 32 and have been taking XR for about 3 months now. Aside from all the benefits, there was always the dilemma of Vitamin C from the point my sister told me it counteracts the effects of the amphetamine salts. My instincts told me this was a wives' tale, so I asked my psychiatrist and he told me this:
'The reason so many people believe this counteraction is such an issue is due to grapefruits.'
Apparently there is something in particular about grapefruit juice, and in particular grapefruit seed extract that does in fact counteract the effects/absorption of amphetamines.
My doctor continued to say that it's not so much what you ingest but when you ingest it and how concentrated the amount of Vitamin C is in the digestive system during the period the salts are bonding from digestion.
It's interesting, because this clarification also applies to the question about the expiry of Adderall. It's not so much the amount of time a substance has till expiration or loss of potency but the conditions in which the substance is stored does in fact contribute to its effective lifespan.
From my conversations about Adderall with other people who utilize it, there is a set of extreme variables in how different people react to the drug and how other substances react with it in their particular system.
So. I suppose I have come to the conclusion that whatever works best for me is indeed the best practice. So long as we all continue to share these experiences and remain somewhat consistent in our approach (experimentation more accurately), we will each not only find that perfect pattern that suits our physiology, but also aide others in methods by which they may benefit and come to the same happy medium.
It is indeed still a tribulation of sorts adjusting various aspects of life with Adderall, such as sleep patterns and appetite and diet and insurance companies, even after time to get the major kinks out.
On my final note - I require 30mg doses 1-2 times a day... my last refill ran me $120 for 60 pills... with an office visit of $90 every two months, that's costing me (with insurance) $165 a month to maintain consistent meds. Of course I am taking XR which has some time until the generic(s) are released from federal clutches.
All in all: it's the most efficient method I have found to regulate the energetic and intellectual anomalies which make up such an integral part of the being I have come to know myself to be to keep myself medicated. As a youth it was quite simple and even empowering to have boundless energy and lightning trains of thought and action. I feel this has taken a bit of a toll on me over the years managing ADHD without the medication. Now that I am somewhat older and have more responsibilities to uphold, it just makes too much sense to spend the money and let the salts do their handy-work.
I still would not recommend medication as a first attempt at managing this condition in a youth. I well understand what my mother meant when she said of me as a child: "That's the way God made him, that's the way I'm gonna let him be." Bless her soul, I owe her so many experiences because of that one decision she made. I'm even more grateful to have been given the opportunity to make the decision myself to experience the difference WITH Adderall.
Who knows, maybe one day I will be able to produce the same results within my own bio-energetic body without being facilitated by the medications on a consistent basis and without much effort. Chemistry does after all have its roots in Alchemy.
So have fun transmuting everyone! Thanx so much for the opportunity to share and receive from this community.
psidre felix
Elandruss 10-06-09, 02:17 PM Hey guys, I have a question, and I figured I'd do a bit of piggy-backing, rather than new post.
Does anybody have any information on how much of a given acid is required to neutralize the adderall? I normally take mine in the morning with a cup of green tea, slightly basic to speed absorbtion, and a little caffein to make the come on a little smoother, or at least that is what it seems to do for me.
I don't take any multivitamins until late in the day, when i'm all done being productive, but will normal foods have a substantial effect? I'm sitting here looking at my plate with my cheese sandwich, a few chips, and a pickle spear, and realizing that vinegar from the pickle is acidic, as well as the cheese. Help!
Roserazzle 10-06-09, 04:48 PM You can eat drink acidic (OJ, grapefruit juice [yuck, does anyone honestly like that stuff?] pickle juice etc) foods, just not WITH your adderall.
Adderall does not sit in your stomach all day and the foods that enter your stomach change as they are being digested.
two hours after you have taken your pills, you can drink what ever you like. It will not effect your adderall effects
ps: I hope everyone is having a marvy day today.
I just got my seasonal flu shot today and for the first time I feel a bit crappy. yay, not.
Elandruss 10-06-09, 08:36 PM Thank you very much! I'll remember to keep a 2 hour limit on it. I took the advice of another thread here, and started to make my meal right when I take my pill, and then eat an hour after I've taken it, so as not to interfere with absorbtion.
Thanks for the info! I hope your flu shot doesn't mess with you too much! I've never had one, so I don't really know. I also haven't had the flu, so I suppose I've dodged that bullet so far.
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