View Full Version : How exactly does extended release work?


space_cadet
01-03-07, 07:25 PM
Hi everyone,

I've been reading this forums for about a month now but this is my first post.

I was recently diagnosed with inattentive ADD and have been prescribed 40mg a day of Dexedrine. I have been taking medications for about two weeks now with very good results except for occasional insomnia.

This is my problem: My doctor told me to experiment with dosages and I am almost positive that he wanted me to take immediate release tabs, so I could get a better feel how they work and when do they wear off.

However,he didn't put IR or ER on the prescription (it just said tabs) and pharmacists gave me 10mg extended release *spansules*. This I only realized next day.

So I googled up a bit to see how is this extended release achieved. Supposedly, it releases d-amps twice, first half immediately after ingestion and the other half 4 hours later. But it is not clear whether it releases 10mg+10mg, (making it 20mg total in one 10mg ER spansule) or 5mg+5mg.

Can someone shed light on this for me? It would really help me taylor my daily dosage. Thanks.


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Matt S.
01-05-07, 10:36 AM
the way that the spansules worked the best for me is to do the same tablet dose and take 2 of them in the morning and 1 in the afternoon and it seems to calm me the best and deliver the same level... ask for the 15 mg tabs if 45 mg dose is okay with your doctor i am starting school soon so ill be ditching the short acting dex for ritalin LA so

space_cadet
01-05-07, 08:32 PM
Thanks, but my question is whether the 10mg spansule releases 10mg now and 10mg later or 5mg now and 5mg later.
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lars
01-05-07, 08:46 PM
10mg spansule releases 5mg immediately & 5mg delayed.

Matt S.
01-06-07, 12:24 PM
the second burst if that is even what you'd call it is released over a prolonged period as opposed to the adderall xr 2 burst whatever ... in vivo

plates11
01-13-07, 12:15 AM
What you do is ring your your doctor and say he screwed up the script and ask for the proper one and just think of the spansules you got as a bonus. :D

Matt S.
01-22-07, 06:32 PM
thats what I'd do...

tallish
06-12-07, 02:17 AM
I am newly diagnosed with ADD,
My Doc did the same, She wrote
Dexodrine 10Mg Tablets,
Walgreen gave me 10Mg Spansules.
When I asked my Doc about this, she has no idea about ER, Spansules,Tablets!!.

fellow worker
06-12-07, 11:58 AM
Whoops. Did you take it back and have Wallgreen's fix it? Those spansules will be less effective, if they're both the same dose. Also, pharmacies should always be told when they've goofed up- the next mix-up might kill someone. Not to be melodramatic... I don't think it'd be lethal, but if your mixup was reversed- 10mg IRs instead of 10mg ERs that person would be in for a surprise when they took double their dose. With some meds, including dexedrine (esp if they had really high blood pressure), that could have some nasty consequences.