View Full Version : PMS depression not just hormone related?


MafaldaMay
04-08-07, 11:57 PM
Although not new, I thought this article was interesting to perhaps understand the positive correlation that seems to exist between ADHD and bad PMS in women.

Taken from: http://www.webmd.com/news/20051025/pms-concern-might-not-just-be-hormones

PMS a Concern? It Might Not Just Be Hormones

Women Who Don't Get Premenstrual Syndrome May Use Their Brains Differently

WebMD Medical News
Reviewed by Louise Chang, MD (http://www.webmd.com/Louise-Chang)

Oct. 25, 2005 -- Whether or not a woman suffers from monthly premenstrual mood swings may be related to how her brain is wired as well as her hormones.

A new study shows that women who experience no menstrual mood changes use parts of their brain differently than women who have PMS (premenstrual syndrome), a condition marked by mood swings prior to menstruation in addition to other symptoms.

Researchers found women with steady moods had heightened activity in parts of their brain thought to control emotions. They say this increased activity may make them less susceptible to the emotional effects of hormonal changes associated with the menstrual cycle.

Brain Plays a Role in Premenstrual Mood Swings

In the study, researchers examined brain scans of 12 women without premenstrual mood symptoms. The brain scans were taken one to five days before the first day of their period (premenstrual) and eight to 10 days after menstruation (postmenstrual).

During each brain scan, the women saw printed words with 80 positive, 80 negative, and 80 neutral connotations, such as "safe," "death," or "bookcase," while performing other tasks.

The results showed that the women had greater activity in the medial regions of the orbitofrontal cortex of the brain during the premenstrual period and increased activity in lateral regions of this area after menstruation.

The orbitofrontal cortex has been linked to emotions, motivation, and decision making, according to the researchers.

Researchers say the changes seen on the brain scans were not reflected in the women's apparent emotional state. Therefore, they suspect that this increased activity in the separate areas of the orbitofrontal cortex influences the ability for women to compensate for the hormonal changes while maintaining a consistent emotional state.

The results appear in the Proceedings of the National Academy of Sciences.

<citations>SOURCE: Protopopescu, X. Proceedings of the National Academy of Sciences, Oct. 24, 2005, online early edition.</citations>

Princess Mess
07-01-07, 07:21 AM
I am diagnosed with PMDD, a severe case of PMS. I am not diagnosed as ADD, but have an appointment this month to determine if I do have it. My PMDD started in my early 20's and that's when I noticed the decline in my concentration, motivation, memory loss and pure laziness and anti socialness.
Is there any documented proof that PMDD can result in ADD? Because i suffer from PMDD at least 10 days a month and spend the other 20 days trying to recoupe. It's a never ending cycle.

Crazy~Feet
07-01-07, 07:24 AM
ADHD is a genetically aquired brain difference, so I would have to say that no, your symptoms would not cause ADHD. Possibly they might cause ADHD-similar symptoms, but then again a lot of things cause this to happen, such as depression or lack of sleep.