hi,

I'm a difficult ADD case. I've not had much success with medicine, and since my current combo. of tegretol and wellbutrin only helps about 30%, I'm trying to figure out other med combos that people use for ADD and the trials it took to get on these. I can't even read paragraphs or complex sentences and this medicine is the best that my current doc. can do. :( :(

So far, I've been on adderall, concerta, celexa, celexa+concerta and have really flipped out on adderrall, mildly flipped out on concerta, calmer but couldn't really focus on celexa and flipped out eventually on celexa and concerta.

No matter which combo. I've tried, I notice that I have trouble with parts to whole and getting the larger picture. This something I have not been informed is a learning disability and I am hoping to use medicine to address it.
I have inattentive add, combined with mood difficulties (exacerbated after my heavy aspartame addiction), combined with intense intense anxiety, combined with APD.

I'm trying to find a new second useful opinion and it would really help to have knowledge of other med. combinations as matched to symptoms. If people wouldn't mind posting their own medicine combo.'s, trials., symptoms that would be really helpful.

-blank

Eesh.

I tried to put this in the spot where I'd get the most attention. Is there a better spot one would name?

Thanks.

EB

I found Adderall to be the least effective prescription medication for treating my innatentive ADHD symptoms. Concerta was better for sure, but Concerta still ranks near the bottom of the list of when it comes to medications that worked best for me.

We each end to respond to these drugs in our own unique ways more often than not, so what works best for one may be the worst thing for another. That being said, here is a list of my favorite 3 ADHD medications which I have found to be heads and shoulders above the rest:

1) Desoxyn

2) Dexedrine

3) Focalin

I have ADHD with Tourette Syndrome, OCD, and Insomnia and up until now I've had some pretty good success with Adderall, Melantonin and Benadryl combo however tomorrow I'm switching to Adderall and Roserem. I definitly emphasize with your frustration, it gets about a hundered times more complicated when your trying to get help for more than one struggle enspecially when medicines to help one struggle tend to exasperate another (example stimulants and anxiety or tics).

I've heard that strattera has helped a lot of people whom have anxiety/mood issues and ADHD together without accentuating the moods and anxiety. A good friend of mine tried TONS of medicinces for bipolar/ADHD/Borderline Personality and finally found that a combination of strattera and depakote worked miricles. I have another friend who struggled with anxiety and ADHD whom tried very low doses of adderall to augment the effects of strattera since at higher doeses the adderall threw her anxiety off the wall. So I guess it's just a really individual thing.

Another thing to keep in mind is that medication is just one part of a treatment plan. Cognitive-Behavioral Therapy, which focuses on changing thought patterns that can negetivly influence moods/anxiety and making changes in how you deal with your anxiety/moods so that they are less debilitating made a huge difference for my OCD-related anxiety. I've heard that CBT is also thought to be first line in treating people with generalized anxiety. It takes work but it can definitly help.

Have you tried any non-medicine treatments?

~Jen

keep in mind Desoxyn is just a pure form of meth...

use it only as a last resort

keep in mind Desoxyn is just a pure form of meth...

use it only as a last resortDesoxyn is just a single isomer of methamphetamine (dextro-methamphetamine) and is not the same as the racemic methamphetamine that is illegal.

As far as Desoxyn being used as a last resort, I disagree with that completely. I have been prescribed every stimulant (except Daytrana & Vyvanse) used to treat this condition since the spring of 1992, and I have found Desoxyn to be the most therapeutic prescription stimulant drug available.

The only negative things I hear/read about Desoxyn come from people who assume it to have the same effect as street meth, or from people who have never tried it. I have never heard/read a single negative report from anyone who has tried Desoxyn. The only negative thing I have found to be true about Desoxyn is the rediculously high price that they charge for the stuff.

I'm not trying to say you shouldn't be taking it but surely it has a higher risk for abuse and is more nuro toxic?

i've tried it before and compared to street meth i would prefer the Desoxyn any day if i was looking for something euphoric.

If it helps you then i'm glad you've found some relief of your symptoms.

I'm not trying to say you shouldn't be taking it but surely it has a higher risk for abuse and is more nuro toxic?
Neurotoxicity of amphetamine/methamphetamine has only been associated with amphetamine/methamphetamine addicts who abuse 100's of mg's of amphetamine/methamphetamine per day, and sometimes 100's of mg's per dose due to their incredible tolerances.

Desoxyn is supplied in 5 mg tablets, and it is extraordinarily rare for anyone to take more than 60 mg a day when using it therapeutically.

60mg of Desoxyn has me speeding quite hard but i'm sure the effects are different for everyone.

my mistake about the Neurotoxicity

'Please note that there is substantial evidence that toxicity to the brain's dopamine system occurs with high (or repeated) methamphetamine use.'

'Tolerance to meth's effects -- where larger doses are required to achieve similar effects -- increases with frequency of use and with experience. A new user's 15mg insufflated experience may be very euphoric and stimulating, while a 20mg bump snorted by a regular user may be barely detectable. Chronic, tolerated users' dosages are generally 2-3 times that of those listed below. These heavy users may go through a gram or more per day.'


sorry for hijacking the thread blank.

'Please note that there is substantial evidence that toxicity to the brain's dopamine system occurs with high (or repeated) methamphetamine use.'Could you please provide us a link to a source (peer reviewed if possible) where we can read more about "repeated" use and an association with toxicity in human beings?

There is certainlly a connection to chronically high doses and toxicity without question, but I have heard of repeated cases of patients taking Desoxyn therapeutically for very long periods of time with no appearant toxic effects.

Along the same line: http://www.addforums.com/forums/showthread.php?t=22230
.

Could you please provide us a link to a source (peer reviewed if possible) where we can read more about "repeated" use and an association with toxicity in human beings?

There is certainlly a connection to chronically high doses and toxicity without question, but I have heard of repeated cases of patients taking Desoxyn therapeutically for very long periods of time with no appearant toxic effects.

Along the same line: http://www.addforums.com/forums/showthread.php?t=22230
.http://www.erowid.org/chemicals/meth/meth_dose.shtml


haha I would love to get you a peer reviewed source but unfortunately I just grabbed the information off of erowid.org. It's a great information source for illegal/legal drugs and they are known for their accuracy.

perhaps you could e-mail them and ask them where they got the information? i'm sure they wouldn't have put it down if it wasn't solid.

i understand ADDers are a bit touchy about their meds because of all the rubish they get from the media and general population.

i'm going to be put on medication soon so i'm sure i'll know how you feel.

http://www.erowid.org/chemicals/meth/meth_dose.shtml


haha I would love to get you a peer reviewed source but unfortunately I just grabbed the information off of erowid.org. It's a great information source for illegal/legal drugs and they are known for their accuracy.

perhaps you could e-mail them and ask them where they got the information? i'm sure they wouldn't have put it down if it wasn't solid.

i understand ADDers are a bit touchy about their meds because of all the rubish they get from the media and general population.

i'm going to be put on medication soon so i'm sure i'll know how you feel.Erowid is a fine site, but information that is not sited with solid sources carries little weight with people who understand real science. Real science is testable, repeatable, and able to be substantiated by peer reviewed sources.

Of the material relating to neurotoxicity and amphetamine/methamphetamine that has been published in peer reviewed journals thus far has only been relating to labratory animals (monkeys, rats, etc.). The amount of methamphetamine that was given to these animals was 350 mg to 700 mg which is approximately 6 to 12 times respectively the recommended maximum human dose of 60 mg. http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=15900317&dopt=Citation

Taking amphetamine or methamphetamine in therapeutic chronic doses has never been shown to produce any neurotoxic effects in humans (or animals as far as I know).
.

Erowid is a fine site, but information that is not sited with solid sources carries little weight with people who understand real science. Real science is testable, repeatable, and able to be substantiated by peer reviewed sources.

Of the material relating to neurotoxicity and amphetamine/methamphetamine that has been published in peer reviewed journals thus far has only been relating to labratory animals (monkeys, rats, etc.). The amount of methamphetamine that was given to these animals was 350 mg to 700 mg which is approximately 6 to 12 times respectively the recommended maximum human dose of 60 mg. http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=15900317&dopt=Citation

Taking amphetamine or methamphetamine in therapeutic chronic doses has never been shown to produce any neurotoxic effects in humans (or animals as far as I know).
.got any sources that state methamphetmaine is not neurotoxic at low repeated doses?

got any sources that state methamphetmaine is not neurotoxic at low repeated doses?
No, because neurotoxicity associated with low doses has never been a problem thus far, and has not caused any researchers to become curious about the possibility of there being a problem. It cost quite a bit of money to conduct research on that level, and to conduct serious research on something that has no indication of even existing is both wasteful of time and money.

The reason researchers have not been curious about repeated low doses associated with toxicity is due to the fact that both amphetamine and methamphetamine have been prescribed therapeutically for about 100 years now. If there was a problem with toxicity associated with repeated low dose there would have been more than enough anti-drug politicians and others who would have demanded further study by now.

i've tried it before and compared to street meth i would prefer the Desoxyn any day if i was looking for something euphoric....but you said that you had yet to be prescribed medications in the legal sense.

60mg of Desoxyn has me speeding quite hard....Desoxyn is not meant for "speeding" of any type.

'Please note that there is substantial evidence that toxicity to the brain's dopamine system occurs with high (or repeated) methamphetamine use.'

'Tolerance to meth's effects -- where larger doses are required to achieve similar effects -- increases with frequency of use and with experience. A new user's 15mg insufflated experience may be very euphoric and stimulating, while a 20mg bump snorted by a regular user may be barely detectable. Chronic, tolerated users' dosages are generally 2-3 times that of those listed below. These heavy users may go through a gram or more per day.'...Insufflation is clearly referring to the illegal street methamphetamine, NOT Desoxyn.

Lars, I certainly do not wish to tread upon your toes in your section, but I cannot help but make a connection between the quoted posts and some posts in my area, ok? Feel free to edit me out if this is deemed unnecessary. :)

Ozchris, I am going to remind you once more that if you wish to discuss addiction, misuse of prescribed medications, or street drugs, you will kindly post in ADDiction and Substance Abuse. That is the only place that talk of this type is considered appropriate.

Thank you CF, I appreciate you pointing that out.

I missed the reference to illegal use completely.

I need to start reading more attentively. :o

Thank you CF, I appreciate you pointing that out.

I missed the reference to illegal use completely.

I need to start reading more attentively. :o:D Glad to help out in any way I can. I sort of got used to checking on this area while you were busy with school remember?

And anyway, ADDiction and Substance Abuse is my section, ya know ;)...and I am just generally one nosy PITA moderator in the end, I suppose.

I'll butt out now! :)

combined with mood difficulties (exacerbated after my heavy aspartame addiction),:eek:
whaaat?!?!!?




thank you for that reminder... i'm dumping out my diet coke as we speak. :D