View Full Version : Abilify


Lafnalot
10-14-07, 12:23 AM
Has any one ever found Ambilify to induce mania in them?

justhope
10-14-07, 02:41 AM
I've never taken it Laf,


The list of stuff below is from www.pdr.com (http://www.pdr.com)
That might help.

There is another article under

http://www.bipolarworld.net/Medications/Antipsychotics/antipsy6.htm
http://www.bipolarworld.net
This is the main link in case the first doesn't work.

It does mention this drug targets dopamine & serotonin...
I don't see anything stating the side effects induce mania? It's the 6th antiphsychotic to be released as an off lable med for BP.

<TABLE cellSpacing=0 cellPadding=2 width="90%" border=0><TBODY><TR><TD width="80%">Brand name:

Abilify

Generic name: Aripiprazole


<TABLE cellSpacing=0 cellPadding=2 width="90%" border=0><TBODY><TR><TD width="80%">Why is Abilify prescribed?


Abilify is used in the treatment of schizophrenia, the psychological disorder that causes its victims to lose touch with reality, often triggering hallucinations, delusions (false beliefs), and disorganized thinking. The drug is thought to work by modifying sensitivity to two of the brain's chief chemical messengers, serotonin and dopamine.

<HR>Most important fact about Abilify


Abilify can cause tardive dyskinesia, a condition marked by involuntary movements in the face and body, including chewing movements, puckering, puffing the cheeks, and sticking out the tongue. This condition may be permanent and appears to be most common among older adults, especially women. Ask your doctor for more information about this possible risk.

Abilify should not be used in elderly patients with dementia-related psychosis (such as the type that may occur with Alzheimer's disease) due to the risk of sudden death, heart failure, pneumonia, and stroke.

<HR>How should you take Abilify?

Abilify should be taken once a day. It may be taken with or without food.


If you miss a dose...
Take the forgotten dose as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular schedule. Do not take two doses at once.


Storage instructions...
The tablets should be stored at room temperature. The oral solution should be stored in a refrigerator and used within 6 months after opening.
<HR>What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe to continue using Abilify.


Side effects may include:
Abnormal dreams, anxiety, blurred vision, chest pain, constipation, cough, fever, flu-like symptoms, headache, insomnia, light-headedness, nausea, neck pain, rash, restlessness, runny nose, sinus infection, sleepiness, tremors, vomiting, weakness, weight gain
<HR>Why should Abilify not be prescribed?


Abilify should not be used in elderly patients with dementia-related psychosis. In addition, this drug should not be used if it causes an allergic reaction.

<HR>Special warnings about Abilify


The risk of tardive dyskinesia (see "Most important fact about this drug") increases with the total amount of Abilify that you've taken. To reduce the risk, the doctor will prescribe the lowest effective dose and resort to long-term therapy only if necessary. If you develop symptoms of tardive dyskinesia, see your doctor immediately. Therapy with Abilify may have to be discontinued.

In rare cases, Abilify has been known to cause a potentially fatal condition called Neuroleptic Malignant Syndrome (NMS). Symptoms include high fever, rigid muscles, irregular pulse or blood pressure, rapid heartbeat, excessive perspiration, altered mental status, and changes in heart rhythm. If you develop these symptoms, contact your doctor immediately. Abilify should be discontinued.

Certain antipsychotic drugs, including Abilify, are associated with an increased risk of developing high blood sugar, which on rare occasions has led to coma or death. See your doctor right away if you develop signs of high blood sugar, including dry mouth, unusual thirst, increased urination, and tiredness. If you have diabetes or have a high risk of developing it, see your doctor regularly for blood sugar testing. Also be aware that the oral solution contains 400 milligrams of sucrose and 200 milligrams of fructose per milliliter.

Because Abilify tends to make some people sleepy, you should be cautious about operating hazardous machinery such as cars until you are certain the drug will not impair your ability.

In a few people, Abilify can cause an abrupt drop in blood pressure when they stand up, leading to light-headedness or even fainting. Use Abilify with caution if you have any kind of heart or circulatory problem, take blood pressure medication, or tend to become dehydrated.

Abilify has triggered seizures in a very small number of patients, and can also interfere with the swallowing mechanism. The risk of either problem is greater among older adults. If you've ever had a seizure, be sure to tell the doctor. Abilify should be used with caution.

Drugs such as Abilify can cause the body to overheat. Be cautious in hot weather and when exercising strenuously, and be sure to get plenty of liquids.

Abilify has not been tested in children or teenagers. Older adults should use the drug with caution.

<HR>Possible food and drug interactions when taking Abilify


The doctor will need to reduce the dosage of Abilify when you take the following additional drugs:

<LIST TYPE="none"><ITEM>Fluoxetine

Ketoconazole



<ITEM>Paroxetine

<ITEM>Quinidine

On the other hand, the dosage of Abilify should be increased when you take carbamazepine.

Be cautious when taking Abilify with blood pressure medications classified as alpha-adrenergic blockers, including doxazosin mesylate and terazosin hydrochloride. Caution is also advised when combining Abilify with drugs that act on the brain, including tranquilizers, antidepressants, sleeping pills, narcotic painkillers, and other schizophrenia medications.

Although Abilify does not interact with alcohol, the manufacturer recommends avoiding the combination.

</TD></TR></TBODY></TABLE>
</TD></TR></TBODY></TABLE>
Table 3. Medications and Substances That May Produce Manic Symptoms

<TABLE border=1><TBODY><TR><TD>Amphetamines
Corticosteroids (including ACTHa)
Methylphenidate
Baclofen
Cyclosporine
Metrizamide (following myelography)
Bromide
Disulfiram
Opiates and opioids
Bromocriptine
Hallucinogens (intoxication and flashbacks)
Phencyclidine (PCP)
Captopril
Hydralazine
Procarbazine
Cimetidine
Isoniazid
Procyclidine
Cocaine
Levodopa
Yohimbine
</TD></TR></TBODY></TABLE>


<SUP>a </SUP>ACTH, adrenocorticotropic hormone

Crazy~Feet
10-14-07, 04:54 AM
I have been taking Abilify for BP agitation, not mania specifically. I have discontinued it due to a rare side effect I seem to get from AAPs. :o

Skully
10-14-07, 08:19 AM
I take Abilify for Bipolar II. I have read that it can induce mania is some occurances (on a webiste, don't remember the address, sorry). If you are feeling that it is for you, talk to your doctor. Maybe an adjustment needs to be made. Dosage may be too high? If you don't mind me asking, what dosage are you on?

Matt S.
10-14-07, 12:50 PM
Abilify, according to one of my old doctor's can be "activating" in bipolar disorder in some people, it is probably similar to the low dose Geodon phenomena, where it can be stimulating. I took 5 mg of Abilify once and dubbed it "de-bilify" when I slept for 3 days.

Crazy~Feet
10-14-07, 02:52 PM
Abilify, according to one of my old doctor's can be "activating" in bipolar disorder in some people, it is probably similar to the low dose Geodon phenomena, where it can be stimulating. I took 5 mg of Abilify once and dubbed it "de-bilify" when I slept for 3 days.At first I had a very sedated and dopey response myself. I dubbed it "Stupify". I was taking Topomax at the time, too. I dubbed that "Stupamax" and called the combo "My Little Set o' Stupidity". :eyebrow:

Man, I was about an eggplant back then...:faint:

Matt S.
10-14-07, 02:53 PM
I did stupamax too, talk about a med from hell.

justhope
10-15-07, 09:26 AM
hmmm I will remember to stay away from it!

Matt S.
10-15-07, 09:34 AM
It has some cognitive effects, that at first when you are a recovering anorexic like me can be overrode (Topamax causes some weight loss) but it will make you an idiot.

Skully
10-24-07, 07:27 PM
Wow, lots have had problems with it. To me it is my miracle drug. Has made a world of difference in me.

pamelaj
10-24-07, 08:17 PM
My daughter takes Abilify. When she started, her dose was very small. Her symptoms got worse. It seemed to be a drug from hell.

When she started seeing a new psychiatrist, she informed us that taking too low of a dose of Abilify could actually make her symptoms worse.

She been on a stronger highly-regulated dose, for almost a year, and doing wonderfully!

I can attest that her new psychiatrist is one of the best in the United States. Also, my daughter does not have ADHD, but she does/did suffer from many behavioral problems.