Yesterday I switched from Adderall 20mg XR to Vyvanse 30mg since I wanted to test out whether Vyvanse does actually offer longer coverage. I notice that once the medication begins to kick in, I experience rather persistent stomach discomfort. Has anybody else encountered this adverse effect, and if so, does it go away once the body adjusts to the new medication? I found Vyvanse to be much smother, both in terms of onset as well as when the medication wears off. I'd like to continue my trial to determine whether it really does offer better coverage, however I don't see how that will be feasible if this stomach issue doesn't resolve itself... Thanks in advance for the feed back!

I had a pretty irritating stomachache the first day I went onto the drug actually, never any issues after that. Hopefully it won't continue for you.

I've been on it since September 26th...I was in the ER on October 4th with my stomach pains, but mine wasn't upper. Mine felt more like my appendix. Alas it wasn't and they sent me home telling me it was because of my medicine. I haven't had any problems since except an occasional upset stomach and getting nauseous when I eat.

Hrm, I get nauseous only if I don't have any food in my belly, and sometimes when the medication begins to wear off. Are you eating any breakfast (even a protein shake/bar or some fruit) in the am?
I've been taking my dose (50mg) like 5-10 minutes before eating some food, so I can give my stomach a bit of a head start in digesting the medicine before starting on the food. I did experience some nasty nausea/gas feelings one morning when I woke up and took it, forgetting to eat breakfast.

Thanks for the responses! With regard to the previous post, I think that was the problem. I'm so used to taking Adderall on an empty stomach, I did the same with Vyvanse. Aftering eating today, I noticed the discomfort has lessened...I will be sure to take the medicine with food tomorrow morning and hope for better results. Thanks again!

I had indigestion the first couple days, after moving from Adderall to Vyvanse, but it has stopped now, and no other problems with it.

Have been taking Vyvance for 4 days now, and have had diarreha every day. I say in a post on the Adderall page that Vyvance is not effective until it reaches the intestines. Well, my intestines do not like it:eek: . Will it go away?

Yeah, I've been experiencing a bit more looseness in my bowels as well, was much worse when I started taking Vyvanse, but it's getting better.