I want you to know that the combo of a psychostimulant ( amphetamine or methylphenidate ) and reboxetine , a relatively selective noradrenaline reuptake inhibitor , works fairly good for me.

I suffer early-onset ( childhood ) OCD as well as mild depression with melancholia or anergia.

The combo works good for boosting energy, motivation and drive and gives me a sense of power.

For me, reboxetine is a miracle. I take the highest dose that is possible ( 12 mg per day ) and my doctor and I have found this dose to be the best.

Even works for my OCD ( in combination with a psychostimulant )

Libido is improved, too :rolleyes:

But reboxetine isn't available in the US , only in European countries. Using online phamacies or shipping by a pharmacieshould solve this problem.


Info : www.reboxetine.com (http://www.reboxetine.com) ( fairly good site )

Further questions: Just send me a private message

good luck

ps: side effects are mild and consist ( for me ) of mild acceleration of heart rate and blood pressure

I remember when reboxetine was first available it was hyped as a remarkable drug to increase motivation with few side effects. In my case only very high doses had any noticeable benefits. I had the common side effect of it stimulating noradrenic receptors in the prostate triggering painful/difficult urination, painfull ejaculation and erectile problems(at all doses). Tamsulosin (Flomax) could counter that side effect.


1: Eur Neuropsychopharmacol. 2002 Aug;12(4):337-41.
Links
Painful ejaculation and urinary hesitancy in association with antidepressant therapy: relief with tamsulosin.
Demyttenaere K, Huygens R.

University Hospitals Gasthuisberg, Department of Psychiatry and Institute for Family and Sexological Sciences, Herestraat 49, 3000 Leuven, Belgium. keon.demyttenaere@med.kuleuven.ac.be

Painful ejaculation has been reported in association with a variety of antidepressants such as the tricyclic antidepressants (TCAs, e.g. clomipramine, imipramine, desipramine, protriptyline, amoxapine), the selective serotonin reuptake inhibitors (SSRIs, e.g. fluoxetine), venlafaxine and the MAOIs. Apart from lowering the dose and changing the antidepressant, no strategies are available to treat this side effect. In this paper, painful ejaculation following the administration of reboxetine is described in two patients. Both patients were treated concomitantly with the selective alpha(1A)-adrenoceptor antagonist, tamsulosin. A re-challenge was performed in one patient. The Hamilton Depression Rating Scale (HAM-D), the American Urological Association symptom index, a (dis)satisfaction item score and the Udvalg for Kliniske Undersoegelser (UKU-side effect rating scale) were used to assess the treatment. Tamsulosin rapidly and completely resolved the painful ejaculation and urinary hesitancy in both patients. A re-challenge in one patient resulted in a prompt reappearance of both side effects. Tamsulosin resolved the problem of painful ejaculation in these patients; however, larger studies are needed to confirm these results.

PMID: 12126873 [PubMed - indexed for MEDLINE]