View Full Version : Chantix as an ADHD drug?


rd111234
01-21-08, 11:50 PM
<TABLE id=HB_Mail_Container height="100%" cellSpacing=0 cellPadding=0 width="100%" border=0 UNSELECTABLE="on"><TBODY><TR height="100%" width="100%" UNSELECTABLE="on"><TD id=HB_Focus_Element vAlign=top width="100%" background="" height=250 UNSELECTABLE="off">The new drug chantix for smoking cessation supposedly is one of the first partial nicotine receptor agonists (meaning it has a less toxic effect?). As you may not know the cholinergic system involves Acetylcholine and there are some people who respond better to nicotine patches than ADHD stimulant medication. Something that stimulates the cholinergic system (which is quite prevalent in the parietal cortex, which isn't necessarily stimulated by the regular ADHD meds. that are out now) can relate to increased spatial orientation and memory to name some of the benefits.

Unfortunately there are limited options available right now for the cholinergic system. One option would be to try out some of the Alzheimers drugs such as Acetylcholinesterase inhibitors (donepezil, galantamine, and rivastigmine), which have lots of peripheral side effects and can be quite dangerous. The other option would be a nicotine patch (even though you're not smoking it, it can still be quite toxic). However, with the partial nicotine receptor agonists being developed by such companies as Targacept and Abbott it seems there may be a new horizon and new treatments that people with different kinds of ADD can try out.

With that being said, the only partial nicotine agonist (more safer than simply going with a nicotine patch or other smoking cessation products) out right now on the market seems to be this Chantix product developed by Pfizer for smoking cessation. How many people have tried this and what are the effects?

According to Wiki nicotine's profile can change from a stimulant (lower amount; smokers usually breath short breaths for this effect I've heard) to a sedative/pain killer in higher concentration dosages. Since chantix is mainly for smoking cessation, wouldn't there be a stimulating effect that can help with inattentive ADD?
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theta
01-22-08, 01:22 AM
Unfortunately there are limited options available right now for the cholinergic system. One option would be to try out some of the Alzheimers drugs such as Acetylcholinesterase inhibitors (donepezil, galantamine, and rivastigmine), which have lots of peripheral side effects and can be quite dangerous.


Also in the US the otc supplement huperzine-A is available. But in the moderate to high dose range it does has alot side effects. I take around 100 mcg daily. I think some studies used 400 mcg daily thats way too much for me.

netsavy006
01-22-08, 03:13 PM
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Since chantix is mainly for smoking cessation, wouldn't there be a stimulating effect that can help with inattentive ADD?


That may not be the case. I don't know for sure but chantix may not be stimulating.
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rd111234
01-22-08, 09:44 PM
<TABLE id=HB_Mail_Container height="100%" cellSpacing=0 cellPadding=0 width="100%" border=0 UNSELECTABLE="on"><TBODY><TR height="100%" width="100%" UNSELECTABLE="on"><TD id=HB_Focus_Element vAlign=top width="100%" background="" height=250 UNSELECTABLE="off">Yeah, it may not be. Being a partial nicotine receptor it could be or may not be depending on how it works. Anybody know or have tried it?
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optimus86
01-22-08, 11:13 PM
In Australia it gained HUGE attention as suicide being one of the side effects, research has documented this as a fact also. Which sux because i want to quit, patches work, but i find myself depressed none the less. maybe something to do with the MAO activity cigarettes have.

wifeandmom
01-22-08, 11:27 PM
Two words regarding Chantix: Carter Albrecht.

http://cbs11tv.com/local/chantix.carter.albrecht.2.507207.html

I wish it WERE a good alternative, but I think the jury's still out.

supamook
01-23-08, 01:27 AM
i'm currently taking Chantix and Adderall 20mgx2/day...

there is a noticable effect for me.

cigs taste "meh" to me...i don't get anything from them now, it's like licking carpet or something. i'm growing very sensitive to the smell of cigs as well. and this is the best...no cravings!! it's the weirdest thing, i used to literally feign for a cig...now, nothing. i pop off to take my lunch at work, and the thought never even enters my head. it's actually quite awesome...

that said, there is a definite emotional difference. the adderall alone is great, but this is different...i'm calm, and just really happy. okay with everything and everyone. very relaxed. feel smooth...dunno how else to explain it :) it definitely affects my mood. with the adderall, i have increased focus, drive, etc., but i still get angry, or frustrated, or happy, or whatever...this just makes me peaceful all day. no fluctuations. more mood altering than helping focus and things (for me).

so, yeah. just my experience! i do wonder what will happen when i finish the 12 weeks. i'm in week two currently.

* i have not taken the Chantix alone; only with Adderall. i have taken the adderall alone though, so my observations are based on the difference between Adderall and Adderall+Chantix.

optimus86
01-23-08, 01:39 AM
wow, ive heard of similar experiences from Chantix, it only became available in australia at the start of january. i thought there would be an interaction between it and adderal. obviously not?

meadd823
01-23-08, 01:57 AM
I am on Chantix for smoking and so is my hyperactive husband - I take Adderall for my ADHD but he doesn't taking any thing for his. The Chantixit doesn't do a darn thing for his ADD at all - I feel tired on it myself - smoking effects my alertness level apparently - Gary is simply slightly more irritable then normal but no increase in his ability to focus or organize.

optimus86
01-26-08, 12:08 AM
me = inattentive add, chantix = 2nd day... intense drowsiness... i dont think it would be a good choice for add. maybe in combo with ADD meds, not sure, yet to try the combo. will let u know if i do.