View Full Version : Avoiding Dex crash?
Any tips for what to do when the effects of Dexedrine wear off near the end of the day or on a day that I don't take Dexedrine after taking it several days in a row?
I get very irritable, grumpy, head hurts, depleted, anxious, depressed, etc.
I know that eating well helps. I wonder if there are specific foods, nutrients or supplements I should make sure to have enough of.
I have found that cannabis does help take the edge off, but I don't want to resort to that too often, because I've found that it can upset my sleep schedule (oversleeping).
Breathing exercises help calm me down a bit. Maybe I should try kava kava herbal tea.
Or maybe I just need to take Dexedrine more often to avoid those days when I'm in a sort of withdrawal?
Retromancer 02-25-08, 12:13 AM You may wish to look in to the sustained release version of dex' which is available in generic form.
If you can, try to take it easy on the dosage and coverage "creep". I know from experience that is easier said than done.
You may also may want to think about stocking up on supplement drinks like Ensure for those times you are too burnt out to eat right.
ozchris 02-25-08, 12:55 AM Cannabis just makes the ADD symptoms you're treating much worse. Not worth taking anything if you're gonna be smoking weed. It's good you're not using it much.
Protein is what you mainly need. Meat, eggs, nuts etc. A multivitamin wouldn't hurt.
Exercise is the thing that helps me although I don't get many negative effects from my Dex. Taking lower doses spread across the week could help...maybe just taking a break on the weekends.
Something else to consider is that Dex. is possibly not the drug for you.
meriellyn 02-26-08, 04:06 PM I don't really get the comedown/rebound with Dex like I did Adderall. The only time I have a problem is if I don't eat often enough or don't eat enough protein. I eat something small every 4hrs or so (usually shortly after I take my dex) and try to make sure there's a bit of protein there each time and feel much better than if I eat "normally" or just eat whatever.
As for the days off... I want off my Dex for about a week recently and didn't feel so hot but I've come to realize that was mainly because of the annoyances of the things it helps me not do, not a withdrawal type thing. It wasn't about the drug not being in my system and having withdrawals, it was about me doing more things like being flighty, being lazy, losing things, forgetting everything, putting my underwear on inside out (lol), etc.
Not the best suggestion but I got through the off week with caffeine. I'm not a big caffeine person normally but I find I do consume it regularly on days I don't take my dex. I don't touch the stuff when I'm on meds though.
I resolve the annoyances of off days by taking it almost daily. I take it all week and occasionally on the weekends, depending on what I have going on. I don't plan to go a full week without it again any time in the near future because it took me another week to get readjusted and unlike Adderall, I do better on dex if I take it every day.
I like kava tea at the end of the day occasionally as well. And I do self-hypnosis/meditation CD thingies. And yoga. But really, dex doesn't make me anxious or cranky at all unless I forget to eat or only eat carbs.
Less Headroom 02-26-08, 05:44 PM The dosages make a difference too. For example, I am on 3 tabs daily, but two are in the morning and the other is at lunch (XL).
If I took 3 or 2 at once, I'm sure I'd feel more of a crash. But he dosages sort of ween me off.
If you're not taking XL then maybe cutting one of your tabs in half and staggering the dosage by an hour or two. Half now, half in one to two hours.
This will help by not taking you up so fast or down so fast.
But if you are actually feeling the ups and downs, I wonder if the dosage or drug is right for you. As a stimulant, I only notice Dex when I'm at complete rest, and then it might be comparable to the body buzz a few good coffees cause. However, everyone is different so this may just be me.
meriellyn 02-27-08, 12:42 PM If you're not taking XL then maybe cutting one of your tabs in half and staggering the dosage by an hour or two. Half now, half in one to two hours.
This will help by not taking you up so fast or down so fast.
But if you are actually feeling the ups and downs, I wonder if the dosage or drug is right for you.
I agree.
Less Headroom 02-27-08, 05:16 PM I agree.
With which part? :confused:
meriellyn 02-27-08, 05:37 PM With which part? :confused:
Uh, the whole part I quoted.
The suggestion of breaking down doses and the idea that if Dex is giving someone marked highs and lows that they're having an issue with, it may not be the ideal dosage or perhaps the ideal med for them.
I'm curious what the OP's dosage and dosage schedule is....
Sublingual B vitamins might help + can't hurt. I take one from trader joes that is very cheap sublingual b6+b12+foilic acid. It only seems to help if I am feeling a bit fuzzy in the afternoon.
I noticed an improvement with rebound by taking a larger first dose and lower doses later in the day (10mg,5mg,5mg seperated by 4hours).
BobC
Less Headroom 02-29-08, 01:02 AM Uh, the whole part I quoted.
The suggestion of breaking down doses and the idea that if Dex is giving someone marked highs and lows that they're having an issue with, it may not be the ideal dosage or perhaps the ideal med for them.
I'm curious what the OP's dosage and dosage schedule is....
OH. OK. I'm just not used to agreement. How very odd. :rolleyes:
I think that the OP, Sonja, should also continue to take her meds on the weekends too. I know my shrink believes that meds should be taken every day.
OTOH, when I couldn't afford a refill for a day, I binged hardcore on sugar. Not sure it helped. But it was compulsive like.
Sugar is unrelated to ADHD. Caffeine would be a far more effective form of self-medication (it's a stimulant like ADHD meds).
meriellyn 02-29-08, 03:34 PM I noticed an improvement with rebound by taking a larger first dose and lower doses later in the day (10mg,5mg,5mg seperated by 4hours).
I do this as well.
flatlinez 02-29-08, 06:21 PM this worked wonders for me: B complex and 500mg phenylalanine (sold separately)
I started a thread on this on the same forum, so have a look at that.
Considering ADHD isn't supposed to have any involvement with amino acids, how is it that phenylalanine helps?
Hmmm. Interesting. I just read that this amino acid can be turned into norepinephrine and dopamine by the body. Perhaps that's why it helps.
Thanks, I might try that out.
Less Headroom 03-01-08, 06:52 AM Sugar is unrelated to ADHD. Caffeine would be a far more effective form of self-medication (it's a stimulant like ADHD meds).
Please learn not to talk about things you don't understand. You really need to read more carefully and learn to distinguish between causal correlations and correlations.
Read very carefully:
High carb consumption is often an ADHD trait. It has no causal effect, so ADHD isn't sugar crazed behaviour. But there is strong enough correlation (i.e. people with ADHD carb binge more than non-ADHDers) that it (carb binging) is given as an example of ADHD behaviour (i.e. the correlation is sufficiently significant that it is almost predictive when considered in relation to other behaviours).
The operations of the brain require three things that are carried by blood, proteins (actually, amino acids, which is what proteins are broken down into), oxygen (like everything else), and glucose. Proteins (amino acids) are the building blocks, glucose is the fuel (over-simplified but true).
So it stands to reason that if ADHD is a product of cerebral (mal)function, the associated carb binging is for a specific purpose - likely maintaining alertness and elevating dopamine levels (which is often believed to be related to rewards, or the anticipation thereof).
Less Headroom 03-01-08, 06:56 AM I do this as well.
Yes, it is as I mentioned previously. You're tapering off your meds.
Please learn not to talk about things you don't understand. You really need to read more carefully and learn to distinguish between causal correlations and correlations.
Read very carefully:
High carb consumption is often an ADHD trait. It has no causal effect, so ADHD isn't sugar crazed behaviour. But there is strong enough correlation (i.e. people with ADHD carb binge more than non-ADHDers) that it (carb binging) is given as an example of ADHD behaviour (i.e. the correlation is sufficiently significant that it is almost predictive when considered in relation to other behaviours).
Take a chill pill, man. You do realise you just ripped into one of the few posts of mine on these forums that was both 100% correct, as well as concise? Verbosity is an issue for me... one which I expect you're about to experience.
Find me some evidence (some studies with sound methodology would be ideal) of your claim that people with ADHD are more prone to sugar binging than the general population.
If you manage that, then find me a study of any level of sugar consumption interacting positively with any of the primary symptoms of ADHD.
You can't simply claim somebody is wrong, act all technical and scientific, but then fail to provide references for proof, man.
The operations of the brain require three things that are carried by blood, proteins (actually, amino acids, which is what proteins are broken down into), oxygen (like everything else), and glucose. Proteins (amino acids) are the building blocks, glucose is the fuel (over-simplified but true).I am fully aware that glucose is the sole energy source for the brain (due to the blood/brain barrier mainly), thank you. But regardless of what you might personally suspect is occurring neurobiologically, sugar levels do not bear any relation (causal or otherwise) to ADHD or its symptoms. :)
Sugar binging first produces hyperglycaemia, then produces hypoglycaemia (due to the body increasing insulin production in response). This all happens within 30 minutes to an hour. The symptoms of acute hyperglycaemia are an indicator of why it is unlikely that hyperglycaemia/hypoglycaemia would be desirable or sought-after.
Symptoms of acute hyperglycemia may include:
* Ketoacidosis
* A decreased level of consciousness, or confusion
* Dehydration due to glycosuria and osmotic diuresis
* Acute hunger and/or thirst
* Impairment of cognitive function, along with increased sadness and anxiety
Neuroglycopenic manifestations
* Abnormal mentation, impaired judgement
* Nonspecific dysphoria, anxiety, moodiness, depression, crying
* Negativism, irritability, belligerence, combativeness, rage
* Personality change, emotional lability
* Fatigue, weakness, apathy, lethargy, daydreaming, sleep
* Confusion, amnesia, dizziness, delirium
* Staring, "glassy" look, blurred vision, double vision
* Automatic behavior, also known as automatism
* Difficulty speaking, slurred speech
* Ataxia, incoordination, sometimes mistaken for "drunkenness"
* Focal or general motor deficit, paralysis, hemiparesis
* Paresthesias, headache
* Stupor, coma, abnormal breathing
* Generalized or focal seizures
This is all temporary and reversible, and not all symptoms manifest in all cases. However, you can see that the symptoms of abnormal sugar levels in the brain are not fun, rewarding or a relief for ADHD symptoms.
So it stands to reason that if ADHD is a product of cerebral (mal)function, the associated carb binging is for a specific purpose - likely maintaining alertness and elevating dopamine levels (which is often believed to be related to rewards, or the anticipation thereof).No. Sugar is known to release tryptophan and serotonin mainly. The reward roll of dopamine is well known, but the exact mode of action, as well as interaction with other neurotransmitters, is not well known (e.g. is dopamine the sole chemical responsible for reward/reinforcement? Is dopamine released whenever we perform any rewarding activity, or only if we do it repeatedly and/or for a certain duration? Hence, is dopamine even released the first time somebody ever experiences a 'reward'? etc). Claims that rewards release dopamine are similar to claims that rewards release endorphins; possible, but not well proven either quantitatively or qualitatively.
Anyway, sugar as a reward isn't really controlled by dopamine. The hypothalamus (area of the brain responsible for dealing with food and appetite, among other things) has specialised glucose-sensitive neurons.
Hence claiming sugar binging releases sufficient dopamine in the brain to improve ADHD symptoms in a (sub)consciously noticeable manner which is different from the experiences of people without ADHD who do the same - that is downright speculation.
Because if it does anything other than that, it's not related to ADHD (but to the population in general, including without bias those with ADHD). Thus my original point stands.
The likely scenario? People with ADHD sugar binge, on average, no more or less than a normal person, and experience the same neurological changes (or likely lack thereof) as a normal person.
I'll give you something: mice which repeatedly consume sucrose do display small elevations in dopamine levels for a couple of minutes; essentially sucrose dependency. However, this elevated dopamine is not detected in binge consumption of sucrose. Further, the mice were starved for 12 hours before being fed each time, causing the brain to try and reward eating. Man I hate animal testing.
Numerous studies have repeatedly demonstrated no causal link or correlation between sugar consumption and increases/decreases in hyperactivity or attention. This includes studies which focused solely on kids with ADHD, as well as studies which focused on a random sample of the population.
However, mothers whose children were given a placebo but told they were given sugar rated their kids as more hyperactive and inattentive than the mothers who knew their kids hadn't had sugar.
The same has been shown to be true for amino acid levels; they are not related to ADHD any more than they are to normal brain chemistry.
It's all well and good to call somebody up, but do try to make sure your own argument is watertight before you do. It's almost as though you simply assumed that my terse method of delivering my quoted claims implied lack of research or thought; I was in fact quite careful and deliberate about the wording of that post you attacked. ;)
I think it would be appropriate to end this post with a quote from you:
Please learn not to talk about things you don't understand.
Though to be honest, I don't even feel that way towards you. I think that people should be encouraged to show their knowledge of ADHD on here, and share it with others. If they make a mistake, they'll more than likely be corrected quickly enough.
We don't want an atmosphere where people are afraid to post due to fear of somebody jumping down their throat if they're wrong. :)
Less Headroom 03-02-08, 05:35 AM You keep getting hung up on causal correlations and ADHD. I have repeatedly said that they are not causally correlated. I even bolded it. Why do you keep pounding on that particular dead horse?
"However, this elevated dopamine is not detected in binge consumption of sucrose."
These mice didn't binge. They weren't acting as if under compulsion or satisfying a craving (which is a kind of compulsion). They were injected.
Sweetness has a purpose, it's how we know fruits and some vegetables are ripe. Like sex, sweetness causes a pleasure response. Injection would bypass this. Mind your confounds, there are only so many conclusions you can draw within the framework of a methodology.
"The likely scenario? People with ADHD sugar binge, on average, no more or less than a normal person, and experience the same neurological changes (or likely lack thereof) as a normal person."
Yeah, so why are they doing research on this right now? (See below.)
We're dragging this thread far off-topic. I've put together a few links for you in the little time attention I'm willing to devote to this. Look for my glucose thread in the scientific discussions forum if you insist on arguing further.
What is ADHD? (symptoms)
http://www.adhd.co.nz/whatis.php
(LH: search "cravings")
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These forums have a section related to eating disorders.
http://www.add.org/articles/eatingdisorders.html
(LH: is it possible that cravings, binging and ADHD are comorbid? I know there's no causal correlation indicating that ADHD is caused by sugar, but is it possible that binges are done in compensation?)
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When sugar (glucose and sucrose) alone is given to [hyperactive] children, they tend to be sedated, with unchanged or even decreased physical activity.
http://www.nutramed.com/children/hyperactivity.htm
(LH: What do they mean? A guy on a forum told me ADHD and sugar are unrelated.)
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"In our clinical practice, we have noted a high incidence of what appears to be carbohydrate "craving" among children with ADHD"
http://clinicaltrials.gov/ct2/show/NCT00011466?cond=%22Attention+Deficit+Disorder+wit h+Hyperactivity%22&rank=5
(LH: hmmm... accredited scientists getting government grants to research the very thing you say doesn't exist?)
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Emerging data suggest higher than expected rates of binge eating occur in subjects with ADHD.
http://www.find-health-articles.com/rec_pub_17958207-attention-deficit-hyperactivity-disorder-adhd-binge-eating.htm
(LH: Um... I promise, I won't gloat... too much.)
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Study Sees a Sugar-Adrenaline Link in Children
http://query.nytimes.com/gst/fullpage.html?res=990CE2DB173FF936A25750C0A9639582 60
(LH: What? Surely a non sequitur.)
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Carb binging boosts brain serotonin by triggering insulin secretion. Amino acids compete with each other for transport into the brain; insulin clears most aminos from the blood but spares tryptophan. This means that insulin surges can give us serotonin surges, at least in the short run.
https://www.oasprod3.com/naturalstresscare/aminoacids.aspx
(LH: Increased serotonin can increase alertness or focus as well as mood. But certainly there's no reason an ADHD person would feel a need for that, consciously or subconsciously. Of course not.)
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Insulin & Dopamine Linked
www.sciencedaily.com/releases/2007/10/071017090131.htm (http://www.sciencedaily.com/releases/2007/10/071017090131.htm)
(LH: carb binges also cause insulin spikes.)
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Glucose metabolism, both global and regional, was reduced in adults who had been hyperactive since childhood. The largest reductions were in the premotor cortex and the superior prefrontal cortex--areas earlier shown to be involved in the control of attention and motor activity.
http://www.ncbi.nlm.nih.gov/pubmed/2233902
(LH: Less glucose observed in the brain of a medication naive ADHD person, I'd bet it has something to do with being understimulated. Wonder if epi levels would be low too?)
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Memory enhancement with posttraining intraventricular glucose injections in rats.
http://content.apa.org/journals/bne/102/4/591.pdf
(LH: glucose, epinephrine and working memory - relevant to ADHD? Long shot, I'll grant.)
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Adrenaline, glucose and memory (p247)
http://books.google.ca/books?id=NDkjjSE43zYC&pg=PA248&lpg=PA248&dq=(adrenaline%7Cepinephrine%7Cnorepinephrine)+(ca rbohydrates%7Csugar%7Cglucose)&source=web&ots=nAbACxLo4y&sig=2QTyK4c-5eEB-tKobtHFw-2gzeY&hl=en#PPA248,M1 (http://books.google.ca/books?id=NDkjjSE43zYC&pg=PA248&lpg=PA248&dq=%28adrenaline%7Cepinephrine%7Cnorepinephrine%29 +%28carbohydrates%7Csugar%7Cglucose%29&source=web&ots=nAbACxLo4y&sig=2QTyK4c-5eEB-tKobtHFw-2gzeY&hl=en#PPA248,M1)
(LH: More of the same, slightly more relevant to humans.)
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"Dopamine is commonly associated with the pleasure system of the brain, providing feelings of enjoyment and reinforcement to motivate a person proactively to perform certain activities. Dopamine is released (particularly in areas such as the nucleus accumbens and ventral tegmental area) by naturally rewarding experiences such as food, sex,[6][7] some drugs, and neutral stimuli that become associated with them"
http://en.wikipedia.org/wiki/Dopamine
(LH: Maybe you should dispute that article, funny that no one else has while it's unproven.
Dopamine and norepinephrine depend on adrenaline, which is stimulated or simulated by carb intake. It's also pleasurable to eat sweet things and to satisfy cravings, cravings definitely play into the types of rewards that have dopamine response, think about it... cravings are compulsions. Potential dopamine and epinephrine stimulation are a likely reason for ADHDers craving carbs, and epi is usually followed by norepinephrine, isn't it? )
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You keep getting hung up on causal correlations and ADHD. I have repeatedly said that they are not causally correlated. I even bolded it. Why do you keep pounding on that particular dead horse?
Yes, you say that, yet you haven't pointed out any particular case where I have done so.
Anyway, I'm hardly about to take lessons on causality from somebody prone to claiming his personal speculation as indisputable fact.
"However, this elevated dopamine is not detected in binge consumption of sucrose."
These mice didn't binge. They weren't acting as if under compulsion or satisfying a craving (which is a kind of compulsion). They were injected.Why do you insist on making things up to suit your needs?
The mice weren't injected, they ate it - by choice.
Sweetness has a purpose, it's how we know fruits and some vegetables are ripe.We have a system designed for this which is independent of dopamine. It is heavily tied to the hypothalamus and the tongue. Sweetness can become addictive, yes, but until then, dopamine plays relatively little role, as I mentioned in my previous post.
Cats do not have taste buds for sweetness/sugar, yet they obviously find food just as pleasurable as humans, no?
Like sex, sweetness causes a pleasure response. Injection would bypass this. Mind your confounds, there are only so many conclusions you can draw within the framework of a methodology.They weren't injected, but well done on the speculation.
Also, you quote decreased physical activity and sedation due to hypoglycaemia as evidence for controlling ADHD, yet these are in fact ubiquitous side-effects which bear no relation to ADHD specifically. Why would you try to claim otherwise?
"The likely scenario? People with ADHD sugar binge, on average, no more or less than a normal person, and experience the same neurological changes (or likely lack thereof) as a normal person."
Yeah, so why are they doing research on this right now? (See below.)
We're dragging this thread far off-topic. I've put together a few links for you in the little time attention I'm willing to devote to this. Look for my glucose thread in the scientific discussions forum if you insist on arguing further.Instead of obfuscating your point by linking to a multitude of abstracts and websites, at least half of which do not specifically relate to both sugar & ADHD and noticeable changes in behaviour or ability, why don't you outline the methodology and conclusion of this study that purportedly links sugar and ADHD to noticeable changes in behaviour/ability?
Just remember this, because you keep forgetting it: an entity that acts on all humans is not evidence of a different relationship between that entity and ADHD. E.g. you said "sugar increases serotonin levels. That must by why kids with ADHD sugar binge." Yeah. Except you can replace "kids with ADHD" with "kids in general". See the problem? Not to mention it's not even known if serotonin is even the reason why people "sugar binge"; you can't just assume it is. You should give a definition of sugar binge, BTW. Does somebody do it once a week? Once a day? Do they eat a normal amount of sugar or do they get hyperglycaemia?
I'm just making sure that sugar doesn't keep getting associated with ADHD (any more than it does normal kids and adults). You wouldn't believe how many laypeople people actually think it produces noticeable changes in behaviour in people with ADHD. :rolleyes:
You seem genuinely interested, so I'd suggest the following study for you to read up on:
Milich R, Pelham WE. Effects of sugar ingestion on the classroom and playground behaviour of attention deficit disordered boys. J Consult Clinical Psychology 1986;54:714-8.
Less Headroom 03-04-08, 12:26 AM To measure cerebral glucose metabolism, we administered 148 to 185 MBq (4 to 5 mCi) of [18F]fluoro-2-deoxy-D-glucose intravenously to 50 normal adults and 25 hyperactive adults while they performed an auditory-attention task.
http://www.ncbi.nlm.nih.gov/pubmed/2233902
This is one done on human adults. When I find the abstract on the mice one I'll link to it.
They introduce the glucose through intravenous injection to avoid confounds. Digestive rates may not be the same from subject to subject, this is a confound. To avoid this confound the methodology must take it into account and their solution was intravenous injection.
If the rats ingested the glucose, then the method is flawed.
I've taken research methods in psych as well as criminology and stats in psych. I do know how to read a journal article.
I didn't obsfucate anything. There are research grants based on the fact that clinicians/therapists report what seems to be a high occurence of binging. There are links between epinephrine and glucose. As evidenced by the members of the forums, eating disorders are comorbid.
Norepinephrine and dopamine are both related to epinephrine and the adrenal gland and the pleasure associated with sweets is likely to, and the pleasure most certainly derived from satisfying cravings likely have an effect on dopamine.
ADHD persons require stimulation and seek out highs. Do you really think a sugar high isn't something we seek out when we feel "off"?
Nothing was obfuscated and the reasoning seemed very apparent the first time. I can't explain it to you any better.
Good luck with whatever it is you're trying to do, but I can't be bothered to keep on with you. I have too many other things I have to fish procrastinating with before I get down to business.
alextai356 03-05-08, 11:10 AM Just a question to those of you who mentioned a high-protein intake – why does that matter? I'm curious as to the answer myself.
ozchris 03-05-08, 06:19 PM Just a question to those of you who mentioned a high-protein intake – why does that matter? I'm curious as to the answer myself.
Protein = brain energy :)
With stimulants you often don't feel hungry and you might not eat much. When the stimulant wears off your body doesn't have enough energy to keep going so the crash is even worse.
flatlinez 03-05-08, 08:39 PM I've heard it put that protein is a long-term energy source. My understanding is that sugar is short-term, and that more complex carbs are somewhere in the middle.
Is there a metabolic element in adhd? Who knows? Certainly if you starve a person or screw with their metabolism their brain function suffers. These effects are very similar to many of the elements of ADHD. So its very easy to think ADHD is simply a metabolic problem.
Negative ADHD effects on my life seem rooted in non-typical reward/motivation response.
Considering reward for eating is a fundamental animal trait. Hunger by its very nature is the most motivating thing possible. (after breathing / water :) )
It seems obvious that carb loading is likley a form of coping mechinism. We have vocablulary like "comfort food" which seem to show a large segment of soiciety finds eating to help satisfy more then just hunger.
Prehaps some in the ADHD subset find a measure of control from eating. I personally found trying to control my ADHD with diet meaningless compaired to stimulants.
That being said eating a balanced diet is important for health in general. One of the bigger pitfalls of stimulants is forgetting to eat. Forgetting to eat causes nasty effects right about the same time the stimulant wears off and is easy to confuse with rebound effects.
BobC
"ADHD is a widespread genetic feature. In the past the ADHD trait was an advantage, but today it simply make our lives a bit more difficult." -BobC
I've been taking it every day in the last week and a half now, to see if it works better this way for me.
It's worse.
I take a 15 mg SR in the morning, and 7 hours later, I'm very grumpy, irritable, depressed, angry at everything.
Arg! Maybe I need to try a different drug. Or raise my antidepressant dosage.
Sonja
flatlinez 04-05-08, 06:09 PM Sonja, I feel for you, because I have had the same problem with Dexedrine.
Please take a look at the thread called "Phenylalanine and B-Complex!" also on the Dexedrine forum. There is a discussion that you might find very helpful.
The gist of it is that I found phenylalanine to be helpful, but the consensus among two other board members is that it must have been a placebo effect, because studies show that phenylalanine does not work like it's meant to (it doesn't reach the brain).
What works, then? Variance recommended the following. Magnesium before you sleep and to take a good multivitamin, good quality fish oil supplement (Omega 3/6's are great) and a good b-complex. 5-HTP / Melatonin may help the anxiety a bit too.Also, I am finding that Wellbutrin fixes the Dexedrine come-down -- you just have to watch out for the Wellbutrin comedown, then!
I have also been taking B-complex for some time now, and several weeks ago I added a high EPA Omega-3 supplement, and even more recently I started to take a liquid Magnesium supplement (as Mincan suggests in the 5mg barr dexedrine thread). This last one is the only one that I can say, with certainty, that it makes a significant and noticeable difference. However, I can only vouch for the liquid version.
Supplements are not entirely accepted by the medical community, and it is possible for them to backfire. Please discuss with your doctor.
flatlinez 04-05-08, 06:13 PM Oh, and I don't know how Magnesium affects the Dexedrine come-down, because I have been taking Wellbutrin for longer than Magnesium. The Magnesium helps with the ADD, though.
I spoke to my doctor and this is what we do now:
Take a 15 mg SR in morning... then 1 hour before the expected crash, take a 5 mg.
For me, a 15 mg lasts about 7 hours, so I take the 5 mg at hour 6.
Sonja
My girlfriend showed me some really helpful guided meditations at end of day that help reduce the crash too. Putting all my stray thoughts and negativity in a glowing bubble in my tummy that expands and expands as I fill it up and it floats more and more and slowly leaves the room, into the sky, the cosmos.
Part of learning to deal with Dex is learning to unwind and decompress, unload everything and the mind at the end of the day after having a superproductive day (that I never used to have when unmedicated).
Sonja, I feel for you, because I have had the same problem with Dexedrine.
Please take a look at the thread called "Phenylalanine and B-Complex!" also on the Dexedrine forum. There is a discussion that you might find very helpful.
Link for those wanting this thread: http://www.addforums.com/forums/showthread.php?t=49194&highlight=Phenylalanine+B-Complex
Abour the sugar binge part, I also get it because of depression.
Marauder 04-11-08, 05:30 AM Maybe I'm lucky don't seem to get anything much in the way of rebound ohh my but if I miss some other stuff I'm on it's far from fun.
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