My doctor prescribe me Prozac two months ago gradely increasing it. I started taking adderall for my ADD/ADHD around the same time. Well the Prozac didn't seem to have any effect the first couple weeks. I felt the adderall effect right away and it's been wonderful!

Anyways I started noticing that everytime I took the Prozac I felt sick, nervous, almost panicking. I stop taking it cold turkey. It was around 20mg a small dosage.

Yesterday I complained, and told him I didn't think I had "major depression" or the feeling of sadness was the main problem. The depression is more from a reaction of being stress and overwhelmed. He said I should try lexapro. Starting me on 10mg.

I took my first 10mg of lexapro today late afternoon. And it was horrible! I felt so drunk, out of it, and tired. I remembering being on zoloft years ago and having the same zombie like numbness feelings. This was alike along with feeling drugged.

Does this mean that lexapro isn't right for me? None of the anti-depress meds never seem to work.

Anti-depressants usually cause some sort of side-effects when starting out, increasing dosage, and/or stopping cold turkey. Give it a few days to a week and you should be fine.

J

You just have to try different stuff. Lexapro has helped me a lot with my depression but makes feel a bit tired and numbed as well. Again, you just gotta try different stuff.
I would suggest giving wellbutrin a go if you havn't. It helped my depression and cognition a bit but made me insanely anxious.
Adderall helps a good deal with my depression and a ton with panic attacks and social ability. It also makes me internally anxious and over revved which leads to frequent feelings of exhaustion.
In my opinion, even though I'm pretty much addicted to it psychologically, adderall can screw up a lot of med regiments. It is harsh in its mechanism of action on the brain and while its effects usually lead to the user feeling more confidence its very benefits can mask negatives it can cause to the user as well as emotional issues the user may still have. The user may now find it possible to ignore these issues because of the increased confidence from the amphetamine, but they will still fester and eventually bite you in the ***. This is just how I have come to see its effects on me.
Don't give up on a med until you have been on that med alone. I thought a lot of meds were awful until I realized that the reason they sucked was because I was adderall simultaneously.

Having said all that, if you are functioning and happy on adderall alone I don't know why the hell you are being prescribed anything else. I will say though that when I first was prescribed adderall I was stubbornly sure I had finally reached the same plane everyone else was on in terms of emotional well being but eventually I realized I was very wrong and I still had a ton of depression and even more certain kinds of anxiety than before I was on adderall.

Good functionality and generally positive emotional well being are pretty much the goals, obviously. Which one of these are you still not happy with that you need to add on more meds in addition to adderall?

I would suggest giving wellbutrin a go if you havn't. It helped my depression and cognition a bit but made me insanely anxious.

I have heard of this drug? What is it mostly use to treat?


Adderall helps a good deal with my depression and a ton with panic attacks and social ability. It also makes me internally anxious and over revved which leads to frequent feelings of exhaustion.

Yes very true for me. I feeling allot more confidence, and handling my stress with schoolwork better. Before I would go in to this stiff state of fear over work and not get anything done. Along with the fear I get lost and don't know where to start. Struggling with ADD/ADHD gave me stressful panic attacks.


Having said all that, if you are functioning and happy on adderall alone I don't know why the hell you are being prescribed anything else. I will say though that when I first was prescribed adderall I was stubbornly sure I had finally reached the same plane everyone else was on in terms of emotional well being but eventually I realized I was very wrong and I still had a ton of depression and even more certain kinds of anxiety than before I was on adderall.

Well I have a history of an eating disorder, self-harm, and social fears. I don't blame my doctor for prescribing me more anti-depression meds.

Long story, I started self harming about a week ago after not harming myself for almost a year and a half. I think what trigger it was feeling stress out and over whelm about school, because I was getting failing grades, and wasn't doing the school work. Personly I think my ADD/ADHD plays a big role with not doing the work. As a reaction I would get stress out, then that builds up making me feel depress.

Now again I don't blame my doctor giving me more meds when there's scars and cuts on my arm. When he prescribe me the Prozac I was just telling him that I felt depress, lost, and don't know where to start.

Apparently neuroscience 101 dictates not mixing amphetamines with SSRIs...but I've never heard of anyone in real life giving a ****. I started taking my zoloft again yesterday because i went back to the dark place. The place where I cannot help but be depressed and I dont want to live in a dark world like the world appeared... of course i probably shouldnt have just stopped taking 30mg of dexedrine as well... wow that day yesterday was the darkest day of my life almost...

Also I was diagnose with anorexia long before I was diagnosis ADD/ADHD. It's no surprise since my mother has ADD, and my brother has asperger's sydrome

And the fact that I would do well in school everytime I starved myself. Most anorexic can't do well in school because of starvation. For me feeling hungry made me more awake, force better, and planing more.

And going into eating disorder rehabs never help. Sitting down all day just made me crazy. I couldn't walk around because the nurse had to watch you.

My suggestion for what is most helpful, Laura, is to first educate yourself about all the different classes of meds and what their general functions are, then research each med individually. Wikipedia is what I often use for this but their information is a bit off sometimes.

Realize that meds' labeled uses on medical sites or where-ever are almost never all the conditions they are used to treat and that you wont get anywhere near if any of the side effects listed.

Do not make judgements on any class or any one medication until you have given it a fair trial and payed close attention to how it is affecting you and your emotions/thought processes. Meds affect every individual differently and every individual med has quite unique effects, trust me.

Keep a journal somewhere detailing exactly how a med is affecting your emotions as well as other side effects you experience.



www.crazymed.us/ (http://www.crazymed.us/) is another great sight for specific med info.

How long have you been on adderall? Has your school work declined since starting it? For me, the internal anxiety/over revved-ness it caused made that freezing up fear that you described even worse for me and I think contributed to me failing out of the school I was in.

If you havn't yet, see a cognitive behavioral therapist. Regular therapy has always been completely pointless for me but CBT actually has some usefully strategies for changing negative thinking and behavior.

While researching meds online is a VERY good way of educating yourself on what your options may be, please consult with a medical professional before changing or stopping your prescribed medication.

As mentioned above, keeping a med journal or chart is a great idea.

How long have you been on adderall? Has your school work declined since starting it? For me, the internal anxiety/over revved-ness it caused made that freezing up fear that you described even worse for me and I think contributed to me failing out of the school I was in.
.

My school work has declined long before taking adderall. The adderall doesn't make me nervous or stress out.

I hate any kind if anti-depression medication I take. All of them make me feel like a zombie.

Does anyone have any suggest on maybe a anti-anxiety, or anti-depression medication's that doesn't make you sleepily or feeling numb? Also I don't want any that could make you gain weight.

My school work has declined long before taking adderall. The adderall doesn't make me nervous or stress out.

I hate any kind if anti-depression medication I take. All of them make me feel like a zombie.

Does anyone have any suggest on maybe a anti-anxiety, or anti-depression medication's that doesn't make you sleepily or feeling numb? Also I don't want any that could make you gain weight.

Tried St John's Wart? It's an over the counter supplement.

I wouldn't take ANY nutritional supplement with your prescribed medication, until you've spoken with a medical professional (or a pharmacist at the very least) about what (if any) potential interactions or side effects it may bring.

Remember, just because its "natural" doesn't mean it is necessarily harmless. This is not intended as a "scare" tactic...it's merely common sense.

I wouldn't take ANY nutritional supplement with your prescribed medication, until you've spoken with a medical professional (or a pharmacist at the very least) about what (if any) potential interactions or side effects it may bring.

Remember, just because its "natural" doesn't mean it is necessarily harmless. This is not intended as a "scare" tactic...it's merely common sense.

Oh yeah, SJW has contraindications: you can't take it with an SSRI or if you're a heavy meth user.

On February 10th, 2000 the FDA issued a Public Health Advisory for certain drugs that may potentially interact with St. John's Wort. A study at The National Institutes of Health (NIH) showed a significant drug interaction between St John's wort and Indinavir, a protease inhibitor used to treat HIV infection. Concomitant administration of St. John’s Wort and Indinavir substantially decreased Indinavir plasma concentrations. Based on this study and reports in the medical literature, St. John’s Wort appears to be an inducer of an important metabolic pathway, cytochrome P450. As many prescription drugs used to treat heart disease, depression, seizures, certain cancers or to prevent conditions such as transplant rejection or pregnancy (oral contraceptives) are metabolized via this pathway, the FDA recommended that health care providers should alert their patients that St. John's Wort use might reduce the effectiveness of their medications. If you are taking any prescription medications, consult with your doctor before using St. John's Wort.

Please see: http://www.fda.gov/cder/drug/advisory/stjwort.htm

(Coloring is mine for emphasis)

Please see: http://www.fda.gov/cder/drug/advisory/stjwort.htm

(Coloring is mine for emphasis)

This is from Australia's FDA equiv: http://www.tga.gov.au/docs/html/alert.htm

TGA alert to doctors and pharmacists and complementary health practitioners

Important interactions between St John's Wort (Hypericum perforatum) preparations and prescription medicines
15 March 2001
The Therapeutic Goods Administration (TGA) wishes to alert doctors, pharmacists and complementary health practitioners to emerging evidence of important interactions between St John's Wort (Hypericum perforatum) preparations and some prescribed medicines. Particularly important are interactions which may lead to loss of therapeutic effect of the prescribed medicines.
St John's Wort is an ingredient in many complementary medicines which are available without prescription from pharmacies, health food shops, supermarkets and complementary medicine practitioners. The content of St John's Wort varies from one product to another. Because St John's Wort preparations are so widely available, patients may be taking them without their health practitioner's knowledge.
The accompanying Information Sheet for Health Professionals (http://www.tga.gov.au/docs/html/info.htm) <http: www.tga.gov.au="" docs="" html="" info.htm=""> summarises the advice received by the TGA from the Adverse Drug Reactions Advisory Committee (ADRAC) and the Complementary Medicines Evaluation Committee (CMEC) and provides guidance on the management of patients.
It appears that preparations of St John's Wort may be inducers of various drug metabolising enzymes. This may result in a reduction in the plasma concentrations and therapeutic effects of medicines metabolised by these enzymes. Because amounts of active ingredients can vary from one preparation of St John's Wort to another, and patients may switch between preparations, the degree of induction is likely to vary.
There is strong evidence to suggest that St John's Wort significantly reduces the plasma concentrations of the following medicines:


indinavir
cyclosporin

There are also reasonable grounds for concern that St John's Wort may reduce the efficacy of the following medicines:


warfarin
digoxin
theophylline
other HIV protease inhibitors (saquinavir, ritonavir, nelfinavir)
HIV non-nucleoside reverse transcriptase inhibitors (efavirenz, nevirapine, delavirdine)
anticonvulsants (phenytoin, carbamazepine, phenobarbitone)

The evidence to support these concerns ranges from specific clinical studies to reports of individual cases or is based on theoretical considerations.
Oral Contraceptives ("the pill") may be affected by the enzyme induction of St John's Wort. Some episodes of breakthrough bleeding reported overseas have been attributed to the interaction. Unintended pregnancy has not been reported but, given the mechanism involved, there are grounds for concern that the interaction might reduce the contraceptive efficacy of some oestrogen-containing Oral Contraceptives.
In addition, St John's Wort products may affect neurotransmitters in the brain and, through this different mechanism, interact with psychotropic medicines including the reuptake inhibitor nefazodone and the selective serotonin reuptake inhibitors (SSRIs) citalopram, fluoxetine, fluvoxamine, paroxetine and sertraline. St John's Wort preparations may also have similarly-based interactions with other medicines which affect CNS serotonin concentrations such as the various triptans used to treat migraine. These interactions may result in adverse reactions consistent with excess CNS serotonin concentrations and may be severe.
Specific advice on dealing with patients who are already taking St John's Wort and one of the medicines listed above is given in the Information Sheet (http://www.tga.gov.au/docs/html/info.htm) <http: www.tga.gov.au="" docs="" html="" info.htm="">. It is important to note that when patients stop taking a preparation containing St John's Wort, plasma concentrations of interacting medicines may rise and result in toxicity. The list of medicines is not exhaustive. The actions of many other drugs depend on their route and rate of metabolism and thus other drugs may also interact with St John's Wort preparations. Doctors and pharmacists are urged to ask patients about use of non-prescription medicines including complementary medicines.
To date, one case of the interaction with cyclosporin and six cases of the interaction with reuptake inhibitor drugs have been reported in Australia. Practitioners are encouraged to report suspected interactions with St John's Wort preparations to the Adverse Drug Reactions Advisory Committee using the postage pre-paid blue cards (http://www.tga.gov.au/adr/bluecard.htm) <http: www.tga.gov.au="" adr="" bluecard.htm="">, distributed with the Schedule of Pharmaceutical Benefits booklet and the Australian Adverse Drug Reactions Bulletin. Additional cards can be requested by telephoning 02-62328386.
A copy of the information sheet (http://www.tga.gov.au/docs/html/info.htm) is available on the TGA website <http: www.tga.gov.au="" docs="" html="" info.htm="">.
The TGA acknowledges the recently distributed advice of the United Kingdom Committee on Safety of Medicines.
Contact for media enquiries:
Dr J McEwen
Director
Adverse Drug Reactions Unit
02 6232 8113
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Thanks for the supporting information!

Bottom line...check with your medical professional before taking nutritional supplements (especially if you're already taking a prescription medication).