View Full Version : [Acetyl-L-Carnitine] new drug but natural


aviv00
05-07-08, 10:16 AM
hello all im new here

just wondering if anyone test it already

did alot of searching but wanna know more

thx for all:)

jmstarry
05-07-08, 12:55 PM
It is an exercise muscle builder. But I am 60a and everything is flaccid. And I mean every THING!!! I have found the Puritan online vitamins and food supplements to be the best prices.
Health food store people usually tell me to give something like sic weeks before seeing any changes, but I will bet it would take L-Carnitine and much more. Hey, is this -ADD - not a structural malfunction ... probably established before birth?
Let me know the science and medical conclusions to date, please.

QueensU_girl
05-07-08, 03:07 PM
It's a great one for weight loss. :)

It is not for sale here in Canadian stores but I did get several bottles from EBAY.COM. Canada Customs let it thru so it must not be technically illegal here. :)

I'd make sure it is from a good manufacturer. (e.g. none of this Made in China stuff; as we learned from the Poisoned Pet Food disaster)

theta
05-07-08, 05:45 PM
I've read acetyl-l-carnitine and r-alpha lipoic acid have some synergistic action
in the mitochondria.

http://www.annalsnyas.org/cgi/content/abstract/1033/1/108

I've used acetyl-l-carnitine in multi-gram amounts and did not notice any over whelming anti-ADHD effects. It is one of the substances that can prevent neurotoxicity from stimulants.

theta
05-07-08, 06:18 PM
1: J Child Adolesc Psychopharmacol. 2007 Dec;17(6):791-802.
Links
Acetyl-L-carnitine (ALC) in attention-deficit/hyperactivity disorder: a multi-site, placebo-controlled pilot trial.
Arnold LE, Amato A, Bozzolo H, Hollway J, Cook A, Ramadan Y, Crowl L, Zhang D, Thompson S, Testa G, Kliewer V, Wigal T, McBurnett K, Manos M.

The Ohio State University Nisonger Center, Columbus, OH, USA.

OBJECTIVE: To determine whether acetyl-L-carnitine (ALC), a metabolite necessary for energy metabolism and essential fatty acid anabolism, might help attention-deficit/hyperactivity disorder (ADHD). Trials in Down's syndrome, migraine, and Alzheimer's disease showed benefit for attention. A preliminary trial in ADHD using L-carnitine reported significant benefit. METHOD: A multi-site 16-week pilot study randomized 112 children (83 boys, 29 girls) age 5-12 with systematically diagnosed ADHD to placebo or ALC in weight-based doses from 500 to 1500 mg b.i.d. The 2001 revisions of the Conners' parent and teacher scales (including DSM-IV ADHD symptoms) were administered at baseline, 8, 12, and 16 weeks. Analyses were ANOVA of change from baseline to 16 weeks with treatment, center, and treatment-by-center interaction as independent variables. RESULTS: The primary intent-to-treat analysis, of 9 DSM-IV teacher-rated inattentive symptoms, was not significant. However, secondary analyses were interesting. There was significant (p = 0.02) moderation by subtype: superiority of ALC over placebo in the inattentive type, with an opposite tendency in combined type. There was also a geographic effect (p = 0.047). Side effects were negligible; electrocardiograms, lab work, and physical exam unremarkable. CONCLUSION: ALC appears safe, but with no effect on the overall ADHD population (especially combined type). It deserves further exploration for possible benefit specifically in the inattentive type.

PMID: 18315451 [PubMed - indexed for MEDLINE]

Not very effective for ADHD.

aviv00
05-15-08, 01:31 PM
im not sure if i have add but i know retalin helps me a lot

even so i taking very low among of it

around 1.5mg - 2 mg for 1-1.5 days

if i take more its effect me more but make me zombie

without it i have too much emotions cant concentrate

emotions takes my concentrate away

theta
05-15-08, 05:28 PM
http://www.addforums.com/forums/showthread.php?p=591373

Thats another current thread on Acetyl-L-Carnitine.