View Full Version : Mixing trimiprimine and reboxetine


tom888
05-23-08, 01:02 PM
who out there knows if i can mix a TCA with an NRI or not?
trimiprimine and reboxetine?

thanks
t

ikgbixcal
09-27-08, 03:25 PM
Trimipramine should not be given in conjunction with or within 2 weeks of, treatment with a MAO inhibitor drug; hyperpyretic crises, severe convulsions and death have occurred in patients receiving MAO inhibitors and tricyclic antidepressants. When substituting trimipramine for an MAOI, wait at least 2 weeks after discontinuing the MAOI, then start trimipramine cautiously and increase gradually.
The drug is contraindicated in the acute recovery period following myocardial infarction. It should not be used in those who have shown prior hypersensitivity to the drug nor in cases of drug induced CNS depression. Cross sensitivity between this and other dibenzazepines is a possibility.

it should be ok