Depressed patients respond more quickly to Organon's Remeron (mirtazapine) than to selective serotonin reuptake inhibitors (SSRIs), according to findings presented at the annual meeting of the International Society for Affective Disorders (ISAD) in Mexico. Patients treated with Remeron were 49 percent more likely to achieve an early response during the first three weeks of therapy than were patients treated with SSRIs, researchers found during a meta-analysis of data from nearly 3,000 patients.

I love this drug! No side effects for me other than a slight increase in apatite and sleepiness (which is good as I am an insomniac). Some complain that it knocks them out completely at first (the effect is more notiable at 15mg than at 30mg or 45mg for some reason) and I'll admit to waking up on the couch a few times when I started taking it.

The problem I had with this med was the increased appetite.....a killer if one is prone to compulsive eating.....In fact this med is often used in nursing homes for seniors who need to put on weight due to loss of appetite and less intake -- and are depressed.....

well it's 2 major side-effects (increased appetite, sleepiness) are the opposite or 2 major ADD stimulant side-effect (decrease appetite, insomnia) so combinning both seems promising!

Remeron was OK stuff but I am unable to simply comply with the directive to just lay down and be in the dark much of the time...and I do not have loss of appetite nor insomnia from my stimulant meds...those are POSSIBLE side effects, the type you need to report to a doctor if they are troublesome, not the normal and acceptable side effects.

I never took remeron but i'm happy taking the zoloft because I know it works for me.

Isn't Remeron one of the atypical class antidepressants? :confused:

Isn't Remeron one of the atypical class antidepressants? :confused:It's certainlly reported to be atypical. It's considered to be an NaSSA (Noradrenergic and Specific Serotonergic Antidepressant).

I remember reading when it first came on the market here in the US about it being described as "the first dual acting antidepressant" in the brochures released by Organon (the manufacturer).

According to Wikipedia's information about NaSSA's: "they are thought to act by noradrenergic autoreceptor and heteroreceptor antagonism combined with specific serotonergic antagonism. This results in increases in both noradrenergic and specific serotonergic transmission."

http://en.wikipedia.org/wiki/Noradrenergic_and_specific_serotonergic_antidepres sant

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Thanks for the answer lars. You seem to know alot about these meds. I'm glad there a people like you willing to help. Thanks again.

Andy.