Sorry for the redundancy -

As I've asked this question before, I'm increasing dosage to 300xl it's my second day on the increased dosage. Is it fairly common to feel tired and zoned out for a few days or a week until your body adjust and you start feeling more awake and alert on the higher dosage? All replies are appreciated, it's been a real pain getting my mood in order

Sorry for the redundancy -

As I've asked this question before, I'm increasing dosage to 300xl it's my second day on the increased dosage. Is it fairly common to feel tired and zoned out for a few days or a week until your body adjust and you start feeling more awake and alert on the higher dosage? All replies are appreciated, it's been a real pain getting my mood in order

In my experience, yes. Going on week 3 of 300xl and the entirety of last week I saw myself zoned out around 3 p.m. at my job (mid-task mind you!) and falling asleep at the computer. I would then go home afterclass and just pass out after dinner because I was feeling so tired. So far since this weekend upto and including today, I have been feeling a lot better.

Yeah , I wonder why that happens... I was on 300 and doing great , I just have to adjust again and stomp out my blues

apparently after reading the prescription pi sheet it says that complete remission and efficacy in depressive symptoms compared to placebo only become noticeable at the 450xl dosage... I guess I need to stay on the 300 for a week or so and titrate to 450xl?

The original dose was 600 a day so going higher is not a bad idea. It does take some time to reign in the depression, though.

******* sucks sometimes... I'm not your average feel depressed , mopey type. Do you know how long your supposed to be on 300 before the jump to 450xl. I have a feeling 450xl would cognitively put me back in the game. I just don't want any sleep issues if thats true. From what I hear wellbutrin is primarily used as an adjunct to many other first line anti'depressants like zoloft or celexa. From what I've read adding wellbutrin to zoloft, celexa or even effexor is quite the combination. I'm at the point where I know I'm smart and I'm ready to squash this blues bug that's been going on for 3 years. I'm done with being flat and mopey..So I guess if I don't have luck at this dose in 2 weeks, I'm thinking of adding one of the other antidepressants...... Ridiculous but something has to be done. Thanks for the replies captain , I'd imagine when your slightly depressed you question everything.

Well, it doesn't work well for everyone. none of the antidepressants do. I felt immediately a lot better, but supposedly a month is necessary to see if it's even working at all for most of them. You can go to a higher dose after a week without too much trouble, but getting your doc to give you a high wellbutrin dose might be tough. If ou do take soemthing else in addition, take a really low dose like 25mg of zoloft and see if that helps.

my doc would likely not hesitate on ramping the wellbutrin dosage up, I metabolize quickly. I do agree that after a 2 weeks on 300xl that from what I hear zoloft added to the equation can be very effective... I'll keep plugging away until then

I am on 300 of the XL right now and have been at that dose for a little less than a month. I just saw my Psych's wife again today. She is a nurse and also has ADHD/ADD, which I actually think is a plus, but I sometimes think it's a little wierd getting scripts from her instead of her husband the Psych. Then again, I have seen plenty of bad stuff from MDs...

Anyway, I have been having anxiety at times and she gave me a script for Xanax. I actually suggested an SSRI, or something in that family, but that's what she came up with.

I would be interested to hear anybody's experiences with Wellbutrin with other drugs for depression, anxiety or OCD. I am wondering if the WB would counteract some of the nasty stuff with SSRI use.

I really think WB is a good drug, and has some usefulness. It's also nice that it's not Schedule II, which can be a pain.

Are the side effects worse at the higher doses? I am thinking of anxiety and sleep issues primarily...

actually I'm starting to feel like myself again on the wellbutrin. I take it along with my stims. From what I hear if you encounter anxiety down the road it's an excellent med to combine with zoloft or celexa , or lexapro for anxiety along with the stims-

ugh, I went off wellbutrin because of the anxiety it causes, but I still have anxiety being off of it now, but to a lesser degree.

I'm thinking about trying Wellbutrin again....I was on it for a while way back when but I really didn't notice any help with my add symptoms. Does it help with yours are you just on it for the anxiety? I'm just wondering.

I don't necessarily have anxiety , I'd say my main issue would be stress and I'd say that overtime I became so stressed that it depressed mel

it's like my mind has finally stopped clinging onto negative thoughts , but god I feel tired on thisl

I tried my 300mg of WB again today, and when the gnawing sensation of anxiety began to grow in my gut, I took an Ativan. It took the edge off beautifully, and I had a great clear, calm kind of feeling. I had taken 5-10mg of Dex as well earlier. Overall it seems like a great combo, and I expect similar results with Xanax.

I find that I feel the need to use less Dex with WB. Rarely do I take more than 15mg a day with it. Usually 5-10.

When I started with the 150mg of WB, I didn't feel anything at all. At 300mg I could definately feel it kicking in. I don't think it does that much for ADD as far as creating focus, but it does seem to have some kind of beneficial emotional effect, provided the anxiety is kept at bay.

Again, I am curious to hear what folks feel when they take the higher dose. Do all of the side effects get worse along with the good stuff?

I would love to take it with a small dose of an SSRI or some such IF I could have all of the anxiety gone, no sleep issues, and no sexual issues. I am completely reliant on sleeping pills at night with WB by itself.

I am wondering if the WB could work with an SSRI to counteract the sexual stuff. It would be great if I could just take two meds every day to take care of everything.

not all there-

so your thinking of dropping your stim? Anyway not all shrinks think the same , some actually do research and practice medicine and study the nuclear aspects of increasing or potentiating the nuclear passageways through augmentation with two antidepressants. From what I was reading from one doctor the presence of true clinical remission of depression and anxiety is not rare but the stats aren't great thats in part due to the limitations of using monotherapy regarding mdd and regular depression and mood disorders. In short yes, wellbutrin has been studied as a great addition to drugs like lexapro, and celexa to name a few. Apparently in regular in mdd "major depression" the adjunct of wellbutrin to celexa is highly effective. I guess that it's not just a few people who don't see results with one antidepressant, rather when combined with the right combination the results of combined antidepressant therapy is becoming much more effective.... I guess certain drugs really are great additions that have proven to increase neural passageways and nuclear functioning in the brain and improve overall mood which to no dismay increases daily functioning and intelligence.

The side effects go away with time, but you have to be good about taking it every day. It is a very useful drug. It doesn't directly attack depression, but it makes you able to ignore bad things better and makes you want to do more stuff, I think. Things are more pleasurable. But it does take some getting used to. It won't make you all manicky like a lot of the antidepressants, which is very nice.

I had a great day today with WB and 15mg of Dex. I didn't need any ativan or xanax to mellow me out either. I just felt focused and mellow and light, and lots of energy. I just have a few days left of my first month of 300mg XL tabs.

It does seem that this drug demands that you stick with it long enough to get past some of the early effects for whatever dose actually works for you, if indeed it does. So far, it seems that 300mg works great for me.

I wouldn't even bother to attempt to sleep without a sedative though. I wonder how bad it may be to always need a sleep aid...

not all there-

I'm on day 5 heading into day 6 on the 300xl. I'm still tired as a mug. Prior to taking the wellbutrin I was basically more so irritable and had ruminating thoughts , basically I hate my job and it drives me nuts. I figure as well as my psych. that in order to focus you can't be irritated or hate your environment all the time. So this week on the 300xl I'm so tired and my short term memory is kind of blank. I guess thats how it helps turn your thought process around. Anyway , did it make you tired like that in the first week or so , I hope it doesn't last too much longer. Today I couldn't tell I took my stims at all... kinda sucks