hey all i just started on bupropion 150 sr. i have been taking it in the mornings for a couple of days and will be titrating up to twice a day next week. i was wondering what time do you guys usually take the pm dose?? i usually take the morning one at about 730-800.

Hi Walking-M,

I'd time it 8 hours out from the AM dose, as the AM dose's half-life will have passed by then. When you can try XL 300, as it is once a day dosing and doesn't wear-off for 21 hours. If your like me, when on the SR version, you will feel when the med wears off - I got a slight crash feeling and energy loss (less then Adderall, but still noticable). I would try to take the PM dose before this occured, when the PM dose wears out - I didn't care as I was sleeping.;)