View Full Version : Dopamine


littleruben
06-17-09, 10:50 AM
let me know if you want the info on the other 3 Ntransmitters - enjoy :)







Much has been written about the mind-body connection. We all know that our emotions and thoughts can effect how our bodies function. Depression can suppress the immune system, anxiety disrupts digestion and anger has an adverse effect on liver function. This connection; however, works both ways – not only do our emotions affect our physical health, but our nutritional status and toxicity levels effect our moods, behavior and emotions.
More and more research is pointing to how nutrient deficiencies and toxicity effect our brain chemistry and how imbalances in our brain’s neurotransmitters (brain chemicals made from amino acids) affect everything from our behavior, ability to concentrate, memory and even organ function.
Research has shown that brain neurotransmitter deficiencies contribute to hundreds of health problems which fall into four categories: physical symptoms (pain, blood sugar problems, immune and digestive dysfunction, etc), personality issues (anger, depression, anxiety, etc.), memory issues and attention issues. I will go over the specific health problems for each neurotransmitter deficiency later in this newsletter.

The Four Aspects of Brain Health
People usually don’t start thinking about the health of their brain until they notice theirs isn’t functioning as well as it used to. It may start by you having trouble remembering names, phone numbers or addresses. Maybe you can’t concentrate as well on the task at hand as you did in the past. You may also notice that you are having more sleep disorders or are feeling depressed more often. These are signs that something may be off in your brain chemistry.
The brain is the greatest generator of electricity in the human body. The brain sends electric currents throughout the entire body through brain chemicals called neurotransmitters which then send energy and information to the rest of your cells, glands and organs. It’s really amazing how perfectly designed the body is when you look closely – the only problem comes when we poison the cells of the body and starve the body of nutrients necessary to fuel cellular regeneration. There are a growing number of toxins that are entering our environment which destroy your brain and nervous system’s cells. These toxins are called excito-toxins which literally stimulate your neurons to death. Toxic chemicals such as MSG, nutra-sweet (aka as aspartame), hydrolyzed protein are now saturating our dietary landscape. Many of us put toxic chemicals on our hair and face which get into our brains and effect the production and function of neurotransmitters. For those of you who have come to my class on detoxification you know how commercial hair, skin and beauty care products are often loaded with toxic chemicals and metals including: lead, aluminum and mercury. All these toxins get into the body and poison the cells. My motto is that if you wouldn’t eat the product don’t put it on your hair, face or skin.
Attention deficit disorder is now one of the fastest growing diseases in our society and it can be traced to these toxins and nutrient deficiencies as well as a disconnected life from nature and spirit.
According to Dr. Eric Braverman, a leading clinician and researcher in the field of mind-brain-body medicine, brain health has four main aspects:
* memory
* attention
* personality and temperament
* physical health
The brain’s four primary neurotransmitters: dopamine, acetylcholine, GABA, and serontonin each affect these four areas of brain health in different ways. For example, one measure for memory and attention is the speed at which the brain processes information. All four neurotransmitters affect speed; however, acetylcholine is most important for brain speed. A normal brain processes a thought in about 320 milliseconds (1/3 of a second). By the time our thinking is slowed down to four hundred milliseconds to process a thought we can no longer process logical thoughts. The average person loses 7-10 milliseconds of brain speed every decade starting at the age of 40. Numerous learning disabilities, neuro-psychiatric problems and other seemingly unrelated health problems are set in motion with slower brain speed. Remember this is just one of hundreds of health issues related to brain chemistry.
The question you may be asking yourself is that if brain speed is a result of neurotransmitter production – what are neurotransmitters made of? Each neurotransmitter is made of different building blocks called amino acids. I will review the specific nutrients and foods that boost each neurotransmitter later.

The Brain’s Four Primary Neurotransmitters
The brain is able to coordinate your movements, control your heart rate and breathing, and allow you to feel hunger, pain, happiness, sadness and all other emotions through the electrical charges which travel throughout your body. This electricity needs a path to travel on through the body. This path is made up of the cells of the central nervous system (which includes the brain and spinal cord) called neurons. Each of us is born with approximately 100 billion neurons which are continually dying and being created every second. Electrical impulses sent as brain signals from the brain through the spinal cord to various nerve endings throughout the body travel from neuron to neuron via brain chemicals called neurotransmitters. Since neurons don’t actually touch each other – there is a gap between each neuron, called synaptic gaps, neurotransmitters bridge these gaps and are, therefore, essential for the brain to communicate to the rest of the body. The electricity of the brain literally travels on the neurotransmitters between neurons throughout the body.
An overabundance or deficiency of any neurotransmitter can lead to health problems. An overabundance of a particular biochemical can flood the synaptic gaps, a deficiency will interrupt the brain signal getting to the part of the body that needs information.
When all four neurotransmitters are balanced one’s brain is operating in top form, or as Dr. Braverman calls it you will be experiencing the “edge effect” – optimum brain function.
To determine your neurotransmitter nature and possible deficiencies contact my office by phone at 708.848.0254 or by email at jim@createvibranthealth.com and I will email you a comprehensive questionnaire which was developed my leading researchers and clinicians in the field of mind-brain-body medicine. In my own case I found the questionnaire results were corroborated by other testing. I can review your results and customize a nutrition, supplement and lifestyle program that can be integrated into your current program to balance any minor or moderate neurotransmitter deficiency. If you have severe deficiencies I can refer you to a holistic medical doctor with more treatment options available for you.
Dopamine
Beta brain waves which make you feel alert are created in the frontal lobes of the brain from neurons that produce the biochemical dopamine, which controls the electrical voltage of your brain. Dopamine works as a natural amphetamine and controls your energy, excitement and motivation.
Dopamine controls the following:
* blood pressure
* metabolism
* digestion
* voluntary movement
* intelligence
* abstract thought
* setting goals
* long-term planning
* Adrenaline production
Those individuals with a predominant dopamine nature who are balanced know what they want, are assertive, strong-willed, fast on their feet and self-confident. Dopamine personalities tend to like facts and figures are highly rational and are achievement oriented. Dopamine types gravitate toward occupations such as law, science, allopathic medicine, engineering, architecture and the military.
Producing too much dopamine can make one too intense, compulsive and driven. Overproduction of dopamine can also lead to violent behavior.
Dopamine deficiencies can lead to some of the following symptoms:
* Anemia
* Blood sugar instability
* Bone density loss
* High blood pressure
* Low sex drive and/or difficulty achieving orgasm
* Joint pain
* Thyroid disorders
* Aggression (paradoxically)
* Anger
* Depression
* Inability to handle stress
* Guilt or feelings of worthlessness
* Excessive sleep
* Mood swings
* Slow thought processing speed
* Forgetfulness
* Attention deficit disorder
* Hyperactivity
* Failure to finish tasks
Severe dopamine deficiencies are often treated with medications or hormones. Mild to moderate dopamine deficiencies can be balanced with diet, supplements and lifestyle modifications.
Physical signs of dopamine deficiency will be fatigue, sleeping long hours and still not feeling rested, your mind wandering, difficulty making decisions, craving caffeine, sexual dysfunction. Unconsciously you will try to compensate by avoiding stressful situations, drinking coffee to give you energy and drinking alcohol to bring you down. It is important once you realize this to correct your underlying dopamine deficiency with proper nutrition, supplementation and lifestyle modifications.
Each of the primary neurotransmitters has a nutrient precursor, and dopamine is derived from the amino acids phenylalanine and tyrosine. Co-factors such as folic acid, vitamin B6, iron, copper and vitamin C are important for phenylanaline to be absorbed.
Common foods that have high phenylalanine (p) or tyrosine (t) concentrations (in grams) include: Chicken 6-8 oz. 1.60 (p)/ .4 (t); Cottage Cheese 1 cup 1.7 (p)/1.7 (t); walnuts 6-8 oz. 1.4 (p); Ricotta cheese 1 cup 1.35 (p)/1.5 (t); Turkey 6-8 oz. 1.6 (p)/.7 (t); Wild game 6-8 oz. 2.6 (p)/1.5 (t).

kattsqueen
06-17-09, 11:04 AM
Im definitely interested in the information you have on gaba acetycholine and serotonin..I believe how they all function with one another is the crux of the problem rather than the approach of individual adjust ments... i think they are all implicated to some degree and different degrees in each individual case..

katts

littleruben
06-17-09, 11:51 AM
cool





Acetylcholine
The neurons in the parietal lobes of the brain, which are seated just behind the frontal lobes and on top of the temporal, produce the biochemical acetylcholine which is associated with alpha brain waves, which control brain speed. Acetylcholine is a lubricant which keeps the cells moist so that energy and information passes easily between cells. It is also the building block for the body’s insulation called myelin, which protects the nerves throughout the body. When acetylcholine levels are balanced your brain operates quickly, one is optimally creative and confident. People with acetylcholine natures are highly innovative, intuitive, flexible and impulsive. Acetylcholine types are very sociable and charming. Relationships are natural to you, unlike dopamine dominants who often have trouble communicating their feelings. Occupations such as therapists, mediators, yoga teachers, social workers, writers, artists and advertising are natural occupations for the acetylcholine type.
Acetylcholine controls the brain’s speed of processing information and is a natural moisturizer that helps cells retain fluids and maintain their membrane coating. All acetylcholine deficiencies lead to dehydration. It is possible to have an overabundance of acetylcholine in which case an individual may feel paranoid and feel that life is taking advantage of them.
Acetylcholine deficiencies can lead to some of the following symptoms and diseases:
* Alzheimer’s disease
* Anxiety
* Dry mouth and cough
* Excessive or frequent urination
* Inflammatory disorders
* Inability to carry out motor commands
* Osteoporosis
* Reading or writing disorders
* Multiple sclerosis
* Bipolar disorder
* Learning disorders
* Mood swings
* Memory disturbance
* Attention problems
* Impaired creativity
* Impaired abstract thinking
Left unchecked a mild to moderate acetylcholine deficiency can lead to a drop in overall health. First one will tend to avoid contact with other people, more tension in your relationships may develop, you will have difficulty managing your schedule, muscles and bones will start to ache, sex will become less enjoyable due to vaginal dryness or difficulty with maintaining and erection. These can be some of the warning signs that acetylcholine levels are dropping.
Nutrition is the key to re-establishing healthy levels of acetylcholine. The B vitamin choline is converted to acetylcholine. Foods highest in choline are: egg yolk, meat, liver and whole grain cereals. My experience with myself and my clients have been that adding 2-3 raw eggs to a fruit smoothie with added flaxseed oil or ground flaxseed meal is a great way to boost numerous nutrients including choline and important antioxidants like vitamins C and E. These antioxidants as well as alpha lipoic acid protect the cell membranes of brain cells from being damaged by toxins and internally generated stress chemistries. One client of mine reversed the vast majority of his MS symptoms by utilizing a diet that included many of these raw-egg shakes.
Other acetylcholine boosters include: phosphatidylcholine and phosphastidylserine – both modified amino acids which help raise acetylcholine levels; DHA – the omega 3 fatty acid; the amino acid taurine; acetyl – L- carnitine and korean ginseng.
Acetylcholine levels can become depleted from the following sources:
· Aluminum toxicity
· Violent and pornographic films and TV shows
· PCBs, chemical fertilizers, pesticides and electromagnetic fields
· Lack of aerobic exercise
Like other neurotransmitter deficiencies a comprehensive program focusing on diet, appropriate supplementation, exercise and lifestyle is the key to balancing your acetylcholine levels.

GABA
Neurons in the brain’s temporal lobes produce the biochemical GABA and their resulting theta brain waves. GABA is the brain’s natural valium providing calmness and aiding in the production of endorphins. When in balance the GABA dominant person is characterized by stability and reliability. These people are team players who thrive on organization and long-term relationships. Homemakers, administrators, technicians, nurses, security officers, accountants, bus drivers are all ideal occupations for GABA natured people. GABA natured people are nurturers and are tend to be very traditional. 50% of the world’s population is GABA dominant so it is very important to understand how to balance this vital brain neurotransmitter.
An excess of GABA can result in a person not taking care of their own needs at the expense of nurturing others.
Early signs that you are may be GABA deficient include: feeling anxious, nervous or irritable. You may start to feel overwhelmed and stressed out. Other symptoms include: allergies, light-headedness, muscle aches. This is just the beginning of what could become serious health problems.
As with all the brain’s neurotransmitters GABA deficiencies affect all four major domains of brain function. Physical, personality, memory and attention issues such as the following can present themselves as GABA deficiencies become more prominent:
* Backache
* Cardiac arrhythmias
* Chronic pain
* Constipation
* Headache
* Hypotension
* Insomnia
* Muscle loss
* Tachiycardia or palpitations
* Urinary frequency
* Anxiety
* Depression
* Guilt or feelings of worthlessness
* Manic depression
* Phobias
* Rage
* Restlessness
* Poor verbal memory
* Difficulty concentrating
* Inability to think clearly
Do these symptoms sound common? Remember 50% of the world’s population is GABA dominant and many millions of these are probably GABA deficient. Many of these symptoms appear in multiple neurotransmitter deficiencies because the neurotransmitters work in pairs. Dopamine and acetylcholine are the electrical “on” switches whereas GABA and serotonin are the electrical “off” switches.
If your GABA deficiency is mild to moderate you should be able to balance it with diet, supplements, exercise and lifestyle modifications. The amino acid glutamine is necessary for the production of GABA. Start with adding foods that are rich in glutamine (Mgs. Per 6-8 oz. serving) such as: almonds 10.3 g., bananas 220 mg., beef liver 6.5 g., brown rice 940 mg., halibut 7.9 g., oats 7.4 g., walnuts 5.4 g., spinach 680 mg..
Additional nutrients to add to your program include: inositol in doses of up to 2-12 grams per day, thiamine 400 mg. per day, niacinamide 100 mg. per day and Pyridoxine 10 mg. per day. Also taking either the herb valerian root or passionflower will boost GABA levels. GABA itself is generally not well absorbed; however, I have found a brand that is easily absorbed.
Aerobic exercise is very important for boosting either GABA, serotonin or acetylcholine. Dopamine is boosted by weightlifting and other anaerobic exercise. Lastly GABA depletion is accelerated by toxic chemicals and metals, especially lead. A hair mineral analysis can tell you if your lead levels are elevated and be brought down with a metal detoxification program.

Serontonin
The brain’s occipital lobes are found near the rear of the brain and control vision and regulate your brain’s ability to rest and resynchronize by producing the biochemical serotonin and its resulting delta brain waves. When your serotonin levels are balanced you can sleep deeply and think rationally, you can enjoy the simple things of life like eating a good meal or going for a walk in nature.
People with a serotonin nature know how to live in the moment. The serotonin type thrives on change and can be impulsive and is not easily deterred. For these people they must enjoy their work or they will start to look for a change. Serotonin types often have excellent hand-eye coordination and mental flexibility. Any occupation that involves operating the most advanced and expensive tools and technology is attractive to serotonin types such as: airline pilots, oil riggers, emergency vehicle drivers, and computer programmers. Increased serotonin levels can often lead one into the more glamorous careers of professional sports, acting and modeling. Serotonin dominance would be helpful for surgeons, chiropractors, detectives, investigators and those who deal with crisis intervention.
Serotonin types are often passionate about their relationships but are tend to be the most independent of the four types and have more difficulty in committed relationships. The serotonin type is interested in excitement whether it is skydiving, mountain climbing or an exciting passionate relationship.
Producing too much serotonin can make one extremely nervous and paranoid. Excessive levels of serotonin can lead to feelings of inadequacy and inferiority and contribute to sadness, depression, anger and desperation for interpersonal relationships which they are, ironically too afraid to attempt.
The early warning signs of serotonin deficiency manifest in symptoms of a disconnect between the mind and body. Some of the symptoms of serotonin deficiency include:
* Allergies
* Hallucinations
* Muscle aches and pains
* Hypertension
* Palpitations
* Urinary frequency
* Light headedness
* Depression
* Codependency
* Loner behaviors
* Impulsiveness
* Phobias
* Rage
* Masochistic tendencies
* Shyness
* Memory loss
* Difficulty concentrating
* Perfectionism
* Restlessness
The early warning signs of a serotonin deficiency may start with a loss of enthusiasm for your favorite activity or a lack of enjoying your favorite foods. Insomnia and lack of productivity may be the next level of manifestation of serotonin deficiency. Finally physical symptoms like weight gain or skin breakouts will get your attention that you have a biochemical imbalance.
In the early stages of deficiency proper diet, supplementation and exercise can correct the serotonin imbalance within a couple of months. The starting point for replenishing your serotinin levels is to eat foods that have plenty of the amino acid tryptophan which the body converts to serotonin. The following foods have high amounts of tryptophan: 1 Avocado (.40 grams), 6-8 oz. of Turkey (.37 grams), 6-8 oz. of Pork (1.00 gram), 1 cup Cottage cheese (.40 grams), 1 cup of wheat germ (.40 grams), 6-8 oz. wild game (1.15 grams).
When you’re deficient in serotonin you will crave simple carbohydrate such as pasta, alcohol and rice as well as salt, all of which promote the release of stored serotonin. It is important to limit one’s alcoholic intake to several drinks per week. The following supplements are helpful for boosting serotonin levels (dosages are dependent on severity of deficiency): Calcium, Magnesium, Fish oils, 5-HTP, melatonin, Passionflower, Pyridoxine, SAM-e, tryptophan, Zinc.
In addition to increasing foods that have high amounts of tryptophan and adding some of the above supplements other serotonin boosting activities include: aerobic exercise 2-3 x per week for 20-30 minutes, prayer, yoga, meditation and chanting which all boost serotonin levels. Avoid foods grown with pesticides which have a particularly adverse effects on serotonin levels.

kattsqueen
06-17-09, 12:10 PM
thank you so much ruben,,,I dont understand what they mean by dopamine and acetycholine being the on switch and gaba and serotonin being the off switch?
do you understand what they mean by working in pairs? can you explain a little more simply for me...

thank you so much katts

littleruben
06-17-09, 02:37 PM
i think they just mean that dopamine and acetylcholine are like...the stimulant or electrical impulses that keep the brain running smoothly and accurately and gaba and serotonin are more of the off switch as in calming or lessening to much activity in the brain Hence:they all work together

selby
06-17-09, 11:44 PM
I'm wondering if taking a supplement can actually increase the amount of a neurotransmitter in the brain. Someone told me that supplements don't cross the blood brain barrier, most of it's absorbed in the stomach and passes through, so it isn't effective?

HypnicJerk
06-18-09, 01:11 PM
This is interesting. Do you have a direct link to Jim's studies (in Illinois, right?) and a bio with his background, perhaps? I'd like to research more about this (and I cannot figure out what is being offered here). Thanks for posting.

Update: Please disregard request. I found the site. Thanks for posting. Anybody trying this?

Mincan
06-18-09, 02:19 PM
Sounds like much psuedo-science. There is a lot stated there without any proof or sourcing.

hollywood
06-18-09, 02:55 PM
mincan,

you hit the hammer on the nail with that one!

HypnicJerk
06-18-09, 04:21 PM
So I downloaded the pdf and read a little closer mainly just out of my interest and an attempt to understand what neurotransmitter is responsible for what. ("this" for depression; "that" for anxiety;" or "the other" for anger) and how it relates to my specific manifestations of one angry, moody, absent-minded and anxious ADD-inattentive.

So it's all just nutrition and environment? (Nothing being said about genetic predisposition?) What?

Annwn
06-18-09, 05:10 PM
These posts are rapidly approaching the level of spam. They are cut/paste info that is poorly formatted and has a bunch of basic information followed by what might generously be called "marketing" information.

Read up on Dr. Braverman and get a different perspective:
http://kidscaretexas.com/Quackery/WQ_Braverman.html


Just because spam comes wrapped in tepid commentary does not mean it belongs on this forum.

HypnicJerk
06-18-09, 07:41 PM
It genuinely was not my intent to perpetuate that. Sorry if it, which is my own desperation/research to understand neurotransmitters and myself (read my non-related threads), sounded like I was jumping on the bandwagon. I removed what I could and have no interest in moving or pushing another's product, service or agenda. And that's all I'll contribute to this thread. Thanks.

littleruben
06-18-09, 08:42 PM
whatever i just thought it was interesting info, calm down

kattsqueen
06-18-09, 10:12 PM
Little ruben i agree with you that the nuerotransmitter research being done is very interesting and i do believe more answers will be found with research into these areas. I have done a lot of reading of studies involving dopamine and its influence on the brain and there is a lot of science behind it...
the more i look the more i see my problems with chronic fatique add and fibromyalgia are related to the workings of serotonin, acetycholine, gaba and dopamine...
It could be that these people are using real science behind a way to make some money? I certainly dont know... I have not lost my interest in exploring these issues,
I am currently not receiving treatment with stimulants because of my high blood pressure (under control with medicine) while googling side affects of low dopamine levels is high blood pressure. Who would of guessed..perhaps going back on stimulants would help my blood pressure, my chronic fatique, my fibromyalgia as well as my add? thank you for sharing

katts
by the way chronic fatique and fibromyalgia also are attributed or related to low dopamine levels
as well as the add

kattsqueen
06-18-09, 11:17 PM
ps littleruben read the article linked at the bottom of the page by hollyduck under similar threads very interesting> I read it the other day
katts

littleruben
06-19-09, 12:46 AM
cant find the link??? can you link me somehow

kattsqueen
06-19-09, 09:55 AM
The link is in the box at the bottom of the page.
variant makes dopamine transporter run backwards;study holly duck

similar threads see under forum jumps just click on underlined title
katts

littleruben
06-19-09, 10:04 AM
Little ruben i agree with you that the nuerotransmitter research being done is very interesting and i do believe more answers will be found with research into these areas. I have done a lot of reading of studies involving dopamine and its influence on the brain and there is a lot of science behind it...
the more i look the more i see my problems with chronic fatique add and fibromyalgia are related to the workings of serotonin, acetycholine, gaba and dopamine...
It could be that these people are using real science behind a way to make some money? I certainly dont know... I have not lost my interest in exploring these issues,
I am currently not receiving treatment with stimulants because of my high blood pressure (under control with medicine) while googling side affects of low dopamine levels is high blood pressure. Who would of guessed..perhaps going back on stimulants would help my blood pressure, my chronic fatique, my fibromyalgia as well as my add? thank you for sharing

katts
by the way chronic fatique and fibromyalgia also are attributed or related to low dopamine levels
as well as the add


your absolutely welcome...i didnt buy any of their crap...just went out and bought dmae and phosphatydolcholine however you spell it to raise my acetylcholine levels.....i truly hope that it helped