View Full Version : Does Desoxyn contain only one isomer?


twinch42085
08-12-10, 02:41 PM
I want to know if Desoxyn consists only of the dextro-isomer, or does it consist of both the dextro-isomer and levo-isomer?

com3origin4l
09-04-10, 02:32 PM
According to the medication guide it is listed as dextromethamphetamine, so I assume just the one.

lolwut
10-10-10, 05:25 AM
Yes, it is only dextro-methamphetamine. The levo isomer is sold over the counter as a nasal inhaler, called "levmetamfetamine" to counter abuse.

dominil
11-16-11, 06:50 PM
yep, what the guy above said lol.

You wouldn't want it to a racemic mixture anyways because the levo isomer causes large increases of norepinephrine which causes alot of those nasty PNS side effects. While the dextro causes very little increase in NE compared to the L-isomer(also little when compared to L- amphetamine. It's also less than d-amphetamine but not by as a great of margin as the to L-isomers)

Reference for the above shenanigans

Hippocampus Norepinephrine, Caudate Dopamine and Serotonin, and’
Behavioral Responses to the Stereoisomers of Amphetamine and
Methamphetamine

Ronald Kuczenski,’ David S. Segal,’ Arthur K. Cho,2 and William Melega2

The Journal of Neuroscience, February 1995, 75(2): 1309-1317



opps kinda rambled on lol.

Bouncingoffwall
11-23-11, 03:45 PM
Agreed with what's been posted.

The "levo" isomer is largely ineffective at producing concentration and clarity in cognition. It affects more of the mid-/lower- brain than dopamine pathways in the outer layers/prefrontal cortex.

It's basically the "bunk" or "dirty" part of the drug.

Then again, meth's Da/Ne potentiation ratio is so much bigger than d-amp's in this regard. Which makes it so profoundly euphoric and addictive at "recreational" doses. 1500x the release of dopamine from baseline in a "normal" (non-ADHD) individual.