ADD Forums - Attention Deficit Hyperactivity Disorder Support and Information Resources Community

ADD Forums - Attention Deficit Hyperactivity Disorder Support and Information Resources Community http://www.addforums.com/forums ADD Attention Deficit Disorder Forums and Chat en Thu, 17 May 2012 02:01:56 GMT vBulletin 60 http://www.addforums.com/forums/images/misc/rss.jpg ADD Forums - Attention Deficit Hyperactivity Disorder Support and Information Resources Community http://www.addforums.com/forums <![CDATA[[Journal] Decreasing Amphetamine Tolerance with Magnesium]]> http://www.addforums.com/forums/showthread.php?t=124352&goto=newpost Thu, 17 May 2012 01:26:37 GMT As many of you know, magnesium has mild NMDA antagonist properties--in other words, it can (in theory) be used to hinder (and in some reported cases, reverse) amphetamine tolerance. This applies to both Adderall and Dexedrine. Keep in mind I am not a medical doctor, so take everything with a grain... As many of you know, magnesium has mild NMDA antagonist properties--in other words, it can (in theory) be used to hinder (and in some reported cases, reverse) amphetamine tolerance. This applies to both Adderall and Dexedrine. Keep in mind I am not a medical doctor, so take everything with a grain of salt. For more information regarding the technical side of this topic, a simple Google search will do wonders. Also, see the below spoiler.

Taken from a previous Blue Light thread:

Quote:

Amphetamine tolerance is caused by excess Ca++ influx through the NMDA receptor gated calcium channels on the outer membranes of the dopamine cells bodies in the ventral tegental area, one of two areas in the brain with concentrations of dopamine producing neurons.
As alluded to above, taking an appropriate NMDA* (partial) antagonist will prevent the development of a tolerance for the effects of an amphetamine or amphetamine-like stimulant. Also, by preventing excess Ca++ influx into the neuron, an NMDA antagonist will prevent associated brain alterations and damage (excitotoxicity).

Studies have indicated that amphetamine tolerance is prevented by exogenous or endogenous agents that are able to inhibit excess Ca++ influx into the neuron through the gated calcium channels on the neuronal membrane that have NMDA subtype glutamate receptors.Glutamate , the body’s major excitatory neurotransmitter, opens the gated calcium ion channels upon attaching to the NMDA receptor. A number of other receptors are also expressed on these calcium channels, which, when stimulated, either facilitate or inhibit glutamate’s action.

I was prescribed about two months ago, and since then, my tolerance to the medicine (d-amp) has skyrocketed. In an effort to control the tolerance, I began taking Cardiovascular Research brand magnesium taurate. I chose that specific magnesium supplement because it has one of the highest bioavailabilities. If you are interested in taking supplements as well, try to avoid magnesium oxide, as it has an extremely low bioavailability of about 4%. The bioavailability of a substance is, in simpler terms, the amount of said substance that your body can actually absorb and use. For example, if you took 100mg of magnesium oxide, your body would only absorb 4mg; the rest would be expelled as waste. Unfortunately, all other forms of magnesium are harder to come by in stores.

I will be posting direct results here, sort of like a journal. I will try my best to stay consistent with my sleep patterns and my diet.

Day 1: May 13th, 2012
~8 Hours of sleep. Avoided acidic foods for breakfast. 15mg Dex ER at 7:10 AM, average up, average down, average school day. Normal side effects during/after comedown: shakiness, lack of appetite, exhaustion, slight lack of motivation. Ingested 2 magnesium taurate capsules at 6:30 PM, noticed a slight boost in energy.

May 16th
Average night of sleep. 15mg Dex ER at 7:12 AM. I have been taking two mag taurate pills spaced out in the PM, usually around 6:00 and 7:00 respectively. Today, I noticed a defined boost in my mood. My mind felt a little sharper as well. The comedown was also a slight bit smoother. I didn't feel quite as depressed or unmotivated. I also noticed that my occasional heart palpitations disappeared for the most part. Good signs! As far as the strength of the medication goes, I haven't noticed any real difference. ]]> Dexedrine/Dextrostat Aphexx http://www.addforums.com/forums/showthread.php?t=124352 Applying things up your butt can be harmful if your taking adhd meds http://www.addforums.com/forums/showthread.php?t=124349&goto=newpost Thu, 17 May 2012 01:04:33 GMT *Be careful when applying things up your butt like enemas and hemmoroidal ointments. This applies to many ssri meds and adhd meds, not limited to just vyvanse. You do not want to be found by paramedics having seizures with a travel pack enema sticking out of you. Thank you and god bless.* ... Be careful when applying things up your butt like enemas and hemmoroidal ointments. This applies to many ssri meds and adhd meds, not limited to just vyvanse. You do not want to be found by paramedics having seizures with a travel pack enema sticking out of you. Thank you and god bless.

Drug interactions between Fleet Enema and Vyvanse

MONITOR CLOSELY: The risk of seizures induced by the use of bowel-cleansing phosphate and sulfate preparations may be increased in patients on concomitant medications that can lower the seizure threshold. ]]> General Medication Discussion TheChemicals http://www.addforums.com/forums/showthread.php?t=124349 Does Wellbutrin negate Vyvanse? http://www.addforums.com/forums/showthread.php?t=124348&goto=newpost Thu, 17 May 2012 00:41:30 GMT OK, it's been a week and I still feel very depressed. I dunno if it's from taking the 0.75 mg Klonopin/day or the Vyvanse not working as it should when taken closely to Wellbutrin (1hr apart) It feels like those two cancel each other out...but it's just my theory. Could it be from taking Mg during the day? I just feel tired, unmotivated and wanna eat all the time.

On Vyvanse alone I never had appetite and actually lost weight but this Wellbutrin makes me want to eat....:eyebrow:

I don't know if I should keep at it, a week is a short time to say if it's helping or not....maybe I'll give it another week. ]]> Wellbutrin 425runner http://www.addforums.com/forums/showthread.php?t=124348 Generics http://www.addforums.com/forums/showthread.php?t=124347&goto=newpost Thu, 17 May 2012 00:00:53 GMT Hi yall. I take 10mg Adderral 3 times a day. I started it in January. Everything has been dandy. Just right. The generic brand I always get is Teva Phar. At the beginning of this month, they gave me some made by Sandoz. i have been sick as dog since I started this. Vertigo, tummy... Hi yall. I take 10mg Adderral 3 times a day. I started it in January. Everything has been dandy. Just right.

The generic brand I always get is Teva Phar.

At the beginning of this month, they gave me some made by Sandoz. i have been sick as dog since I started this. Vertigo, tummy troubles, DEPRESSED, didn't go to work for 3 days, cuz, for real, I just didn't care. (And I'm a girl and had just bought cute summer clothes) - depression doesn't make sense to other people unless they have it.

Anyway, I called my pharmacy and told them I want the other brand and I'll bring these in and trade them. They said first I have to go to my doctor to have my tummy and ears looked at. I did that then called them back and they talked to me like I'm either a drug addict or an idiot.

They said it's a law that I can't trade these in. Why?

My mom is lactose intolerant, and she can only use certain generic brands because lactose is a BIG filler the drug companies use.

anyway, do yall know or have you had experiences like that? It's just stupid that I have to be sick for a month and no one wants to explain it to me.

thanks !

connie

:thankyou: ]]> Adderall conniebky http://www.addforums.com/forums/showthread.php?t=124347 <![CDATA[Johnson & Johnson Patient Assistance Program]]> http://www.addforums.com/forums/showthread.php?t=124346&goto=newpost Thu, 17 May 2012 00:00:33 GMT A change in occupation has left me without insurance & unable to afford my concerta. I've been paying $160 for 30 of the generic at 54 mg each month. I recently came across the Johnson & Johnson Patient Assistance Program. I filled out my portion of the forms & delivered it to my dr for him to complete his portion. He told me a few months ago to let him know if I had trouble paying for my rx.

I was just curious if anyone else has any experience with the program or the application process? I appreciate any insight. ]]> Concerta RamblingRambler http://www.addforums.com/forums/showthread.php?t=124346 Very weird situation http://www.addforums.com/forums/showthread.php?t=124344&goto=newpost Wed, 16 May 2012 23:40:07 GMT Hi guys, got prescribed methylphenidate(ritalin) yesterday morning by a neurologist. 5mg three times a day. I started yesterday, took two. Did not feel a thing at all. Today I took the 3(breakfast,lunch,dinner) and I don't feel anything again. Does this take a week or two to get in the system or w/e? Should I up it too 10mg three times a day? Any insight would be greatly appreciated! Have a nice day ]]> General ADD Talk busterbuzz http://www.addforums.com/forums/showthread.php?t=124344 What meds will work for me? http://www.addforums.com/forums/showthread.php?t=124343&goto=newpost Wed, 16 May 2012 23:33:50 GMT I was finally diagnosed with ADHD-PI last year, and I can't seem to find an effective med. I've tried 20mg/day of Adderall, then Adderall XR, then 50mg of Vyvanse. Adderall and Vyvanse both work well, for a little while. I feel not only focused, but content, sociable and optimistic, but even the Vyvanse seems to only last about 5-6 before I comedown. The comedown sucks. All the positive effects of the drug reverse. I feel more down, scatter-brained, introverted and pessimistic than I normally do, and this is just by afternoon. A booster dose would help, but I have trouble sleeping on these meds already.

My doc tried Strattera, and all it did was make me irritable and give me insomnia. I think the dose might have been too high, but I'm switching docs now and I want some ideas to bring into our appointment. I'm losing hope that any med is going to help me without having intolerable side effects.

Any suggestions? Would other stims be any better? A combination of drugs, perhaps? ]]> Adderall fscott http://www.addforums.com/forums/showthread.php?t=124343 Is therapy worth it? http://www.addforums.com/forums/showthread.php?t=124342&goto=newpost Wed, 16 May 2012 23:11:29 GMT I've been unemployed since last August, failed the CPA exams and feel totally worthless. Can't even finish filling out a job application cause I'm just not all that excited about it anymore, having done about a 100....and only got 4-5 interviews.

At this point, I don't know whether to just focus on passing the exams before my unemployment expires or start looking for a job now...but I feel mentally drained. I take Vyvanse 70 mg for ADHD, Wellbutrin XL 150 for depression (been taking that for a week now) and Klonopin 0.75 mg/day to sleep and help with anxiety.

I'm a very private person and prefer to keep to myself hence the dillema about seeing a therapist for an hour! What if I don't like him...can I just walk out after 10 minutes? I'm not sure they can even help with ADHD issues - like trouble with authorities, etc. etc. ]]> General ADD Talk 425runner http://www.addforums.com/forums/showthread.php?t=124342 Baaaaad evaluation http://www.addforums.com/forums/showthread.php?t=124341&goto=newpost Wed, 16 May 2012 22:51:43 GMT Yeah, so I just got my year-end evaluation and it was ... not good.

For the last few months I've been really struggling with the chaos monster and, frankly, losing. Projects going unfinished, running terribly late, work not getting done or forgotten about, no feeling of engagement, irresistible desire to avoid, run away, hide. Leaving early, making excuses to not come in. Aaaaaall those chaos chickens came home to roost today, and I think the only reason they didn't just fire my *** is that when I do produce work it's good work, and the big boss -- the one who doesn't have to actually manage me -- loves my stuff.

In my foolish youth, I would have thrown in the towel immediately. Let the chaos monster win, quit just before being fired, sit at home depressed and angry. But I'm a middle aged single mother now (a failed ADHD marriage? You don't say!), and with the insufficient but hard-won amount of maturity I possess I know that their criticisms are completely right, I have been dropping the ball egregiously, I don't deserve to be here if I can't get it together, it's totally me.

In that illogical ADHD way, I am galvanized by crisis. Now I am all hepped up to put a scaffold of structure around myself and salvage this career downslide before it goes over the edge.

I'm not actually asking for advice, I think I just wanted to vent to people who probably understand and have been there. The struggle never ends, does it? ]]> Careers/Job Impact mafalda http://www.addforums.com/forums/showthread.php?t=124341 Exams, peak hyperactivity and innattention and Meds http://www.addforums.com/forums/showthread.php?t=124340&goto=newpost Wed, 16 May 2012 22:25:23 GMT Good evening my fellow attention and rest challenged folk. Its 11.15pm and my exam season begins tomorrow. I AM FU**ED. My uni have been kind enough to set my exam at 4pm till 7pm (I have an extra 30 mins to complete and an hour in breaks for the ADHD) which t would happen to be 1) The funky... Good evening my fellow attention and rest challenged folk.
Its 11.15pm and my exam season begins tomorrow.
I AM FU**ED. My uni have been kind enough to set my exam at 4pm till 7pm (I have an extra 30 mins to complete and an hour in breaks for the ADHD) which t would happen to be
1) The funky concerta fail part of the day and the moment when concerta hands over its job to IR ritalin
2)The peak time in the day of my hyperactivity and restlessness
3) The point in the day at which my belly feels ready to tolerate food and makes life miserable until I eat

I wonder whether moving my meds around tomorrow may help or just knocking back 20 mg IR before the exam would be the best thing to do. I can't figure out a good timescale for meds and am ****ting myself about my ability to focus for tht long ahhhh. Any thoughts will be most welcome at this point, as obscure as you like I'm feeling desperate :p ]]> Adult Education Florence1989 http://www.addforums.com/forums/showthread.php?t=124340 Losing track of days? http://www.addforums.com/forums/showthread.php?t=124339&goto=newpost Wed, 16 May 2012 21:51:48 GMT Anyone else have a hard time remembering what day of the week it is. I know now today is Wednesday ( in my part of the world anyway) but most of the time I always think it's a different day than it actually is ]]> General ADD Talk PookDo http://www.addforums.com/forums/showthread.php?t=124339 <![CDATA[Socializing - I don't get it]]> http://www.addforums.com/forums/showthread.php?t=124337&goto=newpost Wed, 16 May 2012 21:07:05 GMT What motivates the average person to keep talking on and on with people? When I was a kid, socializing was associated with "playing". There would be something to DO. That would be a large part of why we were there. Can anyone enlighten me? ]]> Inattentive ADD sbcy http://www.addforums.com/forums/showthread.php?t=124337 Concerta, ADD, and My Situation (Generally Depressed) http://www.addforums.com/forums/showthread.php?t=124336&goto=newpost Wed, 16 May 2012 20:48:16 GMT _General info:_ Hey everyone, this is my first post and I just wanted to get feedback on this situation im in. I take concerta 54mg in the morning and a 10mg Ritalin when I get home from school. _Introduction_ General info:

Hey everyone, this is my first post and I just wanted to get feedback on this situation im in.

I take concerta 54mg in the morning
and a 10mg Ritalin when I get home from school.

Introduction

I came home from school today frustrated and down, I was adding my life and school up and my mind was telling me to dislike all of it. Part of me thinks its the concerta, part of me thinks I've been generally depressed all my life because of my ADD. (One thing leads to another..)
Whether it be my realization that 'I HAVE ADD', and 'I NEED MEDS', or the actually medication, I feel different. I feel like I am being transformed into an addictive monster who while eventually grow out of control. Im 80% sure concerta is working with me, but 20% is saying "___, this just isn't for me".

Diagnosis/Background of my symptoms

Ever since I felt anything from this med, I keep telling myself how much society sucks and all the kids in my school suck. A year ago I took an IQ given by a psychologist who's specialty is these tests. I took the test because my parents noticed how disorganized and how faulty my memory was. Generally, I would come home, procrastinate, play computer games, look random stuff up, eat dinner, lie and tell my parents I did my homework. The next day I would try to do my homework, but couldn't remember any of the assignment and didn't pay attention in class that day, leading to more procrastination/seeking a new thrill to get my mind of homework. The only classes I really enjoy and have enjoyed in high school are some of my Art classes, and Band which was usually fun for me since I love music of most genres, and playing (and i rarely practiced of course.. I rarely practice anything involving school or something I don't like)

So, we went to this Psychologist, she gave me this test which was quite lengthy (around 6 hours long, which i took in two sittings). I scored superior intelligence with signs of mild ADD. We never acted on any meds until this month (I took the test around a year and a half ago). My parents were hesitant because at this time I was also dealing with a growth issue. I was 5 inches shorter than I am now and stood around 5' in the beginning freshman year, and have always been the small kid and that mentality stuck.

Concerta
I was prescribed Concerta about a month ago. After two visits and a phone call the psych I have reached this dosage. He told me to take 2 18mg's since I didn't feel the effects after the first week. Another week or so went by and I met with him, and I could see something working when on 36mg's, but nothing drastic. (I also experienced annoying dry mouth for a few days) Since the dry mouth went away and there were no terrible side effects, he bumped me to 54mg, and I could see the concerta was wearing off when I got home from school, so he also prescribed a 10mg Ritalin to take as a "homework booster".

Effect on my life/mood (+more background info)

ADD has led me into a slump in school and society. I always feel a bit different than friends and other students. No one understands why I could be doing this poorly in school (around a 3.0gpa, not terrible, but not proficient) when I am a smart guy and tend to show an interest in many things. (I love philosophy/space/science and all that, I would watch NOVA as a little guy religiously) Socially, I tend to laugh a bit too much at some things and have a pretty low self esteem. Even after 'getting with' around a dozen girls, and 2 (one being a bit older than me) I still think of myself lowly and 'different'. I am told I am an attractive kid by adults and some girls, but I am decently short, and tend to have a mentality where my mind will assure myself that I don't look good, not to an extreme extent, but I do spend much time in the morning fixing my hair or getting dressed.

To break it all down..

I AM indeed realizing maybe the popular kids aren't my ideal friends, and I always try 'figuring out' why or how they became or are popular.

I DO realize that I need to get organized for school if I want to hold a decent lifestyle so I can stay away from people I do not want to live or work with.

I DO feel a bit depressed sometimes, NOT suicidal and have never self harmed, but I can get frustrated when alone when I question some of my actions and future.

I WISH I could find some real friends who were just like me I have many aquantances, and a few good friends from other schools nearby, but I feel like most of them are either obsessed with "Getting it in" with girls (who are usually not very attractive, but slutty), or they spend all their money and effort into marijuana (which I do sometimes enjoy smoking but also tends to give me short episodes of anxiety if i smoke too much).

I WANT to get on track with my life and sort out my priorities, so i can be a confident and eventually successful kid who people can look up to.

.

I am aware ADD is only effective with specific parts of my brain, but the way that it effects my education,has generally made me a bit depressed and lacking a strong self esteem and I believe the concerta is not helping these feelings.

Anyone who has ever had their life be affected by finding the right friends, ADD, and or concerta/other ADD meds please respond and share your words. It will be a BIG help, I just want to know that there are people out their who know what it feels like to be a kid growing up in similar shoes to mine, and/or any advice they have to offer me.

Thanks so much ]]> Concerta ADDingItUp http://www.addforums.com/forums/showthread.php?t=124336 Quick Sexual Orientation Poll http://www.addforums.com/forums/showthread.php?t=124335&goto=newpost Wed, 16 May 2012 20:46:04 GMT xxxxx xxxxx ]]> Abi http://www.addforums.com/forums/showthread.php?t=124335 Fasting http://www.addforums.com/forums/showthread.php?t=124334&goto=newpost Wed, 16 May 2012 19:56:10 GMT Nothing related to adhd but im on day 2 of a fast. Just had to get that off me chest. Nothing related to adhd but im on day 2 of a fast.
Just had to get that off me chest. ]]> Chit-Chat electrogen http://www.addforums.com/forums/showthread.php?t=124334