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Old 04-16-07, 04:54 AM
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meadd823 meadd823 is offline
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How important do you think *dopamine* is for treating ADD? Is it really dopamine that ADDers lack? Or is it just the norepropine which matters?

The Dopamine Transporter and Attention-Deficit/Hyperactivity Disorder

Medications for ADHD interfere with dopamine transport by brain-region- and drug-specific mechanisms, indirectly activating dopamine- and possibly norepinephrine-receptor subtypes that are implicated in enhancing attention and experiential salience. The most commonly used DAT{solute carrier neurotransmitter transporter dopaimne}-selective ADHD medications raise extracellular dopamine levels in DAT-rich brain regions. In brain regions expressing both the DAT and the norepinephrine transporter (NET), the relative contributions of dopamine and norepinephrine to ADHD pathophysiology and therapeutic response are obfuscated by the capacity of the NET to clear dopamine as well as norepinephrine. Thus, ADHD medications targeting DAT or NET might disperse dopamine widely and consign dopamine storage and release to regulation by noradrenergic, as well as dopaminergic neurons.***End Quote

{part in these added by me for information perposes}


Hope this helps. . . . . .I know simply you asking the question helped me. . . .gotta a medical search engine bonus while looking your infornmation up. . .
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