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Dexedrine/Dextrostat (dextroamphetamine)

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  #1  
Old 03-23-06, 11:56 AM
Allison78 Allison78 is offline
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a handful of Dex questions

I've been on Dex for about a month now, after switching from Ritalin. I'm really liking it. Right now I'm taking 20 mg., twice a day (before I leave for work, and again after lunch.)

The appetite suppression, although not the reason I'm on it, is a very welcome side effect. I've dropped six pounds since starting it. (I'm still a good 40 pounds overweight, so no health concerns with the weight loss.)

I find that the focus is good, BUT...there's a difference from Ritalin. On Ritalin I felt much more wired, more jittery, more "GIVE ME SOMETHING TO DO WHAT CAN I DO GIVE ME SOMETHING TO DO." On Dex I feel much calmer. It's almost a content feeling. Once I start something, I have great focus for working on it, but I find that I still have to exercise self-control in choosing WHAT to direct that focus towards. I can be very focused on, say, posting on an ADD board, when I'm actually at work and should be working. (Uh, just a hypothetical, of course.)

Also, when I refilled my script yesterday I got the Mallinckrodt brand (I'd been using Barr) so am excited about that, as I've read the previous threads about it.

I am wondering what the average daily dose is? I'm at 40 now, and I think my doctor is going to be reluctant to go much higher, even though I wonder if I might benefit from it. One thing I've noticed is that Dex in combination with Xanax helps my social anxiety, which is great, and I want to experiment to see if I get even better benefits from higher doses.

Also, I am shortly going to switch my AD from Zoloft to Effexor. Is it OK to take Dex and Effexor together? It almost seems like they'd help each other if Dex stimulates norepinephrine production (am I correct on that?) and Effexor inhibits the reuptake.

Thanks!

Last edited by Allison78; 03-23-06 at 12:00 PM.. Reason: added more questions
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Old 03-23-06, 09:41 PM
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I am still trying to find out if dexamphetamine is the same as dexadrine??? I feel the same on daxamphetamine as you do...
I really should go google it
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Old 03-26-06, 03:07 PM
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Keep in mind that the Xanax type drugs (incl. Ativan, Serax, Klonopin, Valium) can cause memory and learning problems

If you have a job that requires learning/memory, you might find it is affected.

Also, there is an increased risk of falls (as there also is in those who use sleeping pills). People get up, they are woozy or their motor control and coordination is affected, and down they go.

A lot of older people come to the ER with a broken hip or forearm due to a fall sustained on tranquilizers/sleeping pills. They fall asleep, then have to pee, get up (it is often dark), they are weak and they fall down.

One doctor i know calls Ativan and Xanax -- "Gin in a pill". Quite bluntly, they cause impairment.

The gold standard is to Prevent Anxiety. Usually docs prescribe Paxil.

Anti-anxiety pills set up a vicious circle b/c they wear off. This wear off can create a higher state of Anxiety, tension and tearfulness.

They also never really teach a person Skills to deal with the stressors that are making them upset.
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Old 03-26-06, 05:26 PM
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You could say the same thing about ADHD medications, and you'd have a significant grain of truth.
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Old 08-01-08, 06:48 PM
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Re: a handful of Dex questions

Dexedrine is a brand name of d-amph
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Old 08-02-08, 02:25 AM
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Re: a handful of Dex questions

Quote:
Originally Posted by Allison78 View Post
The appetite suppression, although not the reason I'm on it, is a very welcome side effect. I've dropped six pounds since starting it. (I'm still a good 40 pounds overweight, so no health concerns with the weight loss.)
I lose a few pounds when I'm on dex. For me this is a pretty big deal because I'm already borderline underweight without dex. I've found the weight comes back pretty quickly after stopping dex for a while.

Quote:
Originally Posted by Allison78 View Post
I find that the focus is good, BUT...there's a difference from Ritalin. On Ritalin I felt much more wired, more jittery, more "GIVE ME SOMETHING TO DO WHAT CAN I DO GIVE ME SOMETHING TO DO." On Dex I feel much calmer. It's almost a content feeling. Once I start something, I have great focus for working on it, but I find that I still have to exercise self-control in choosing WHAT to direct that focus towards. I can be very focused on, say, posting on an ADD board, when I'm actually at work and should be working. (Uh, just a hypothetical, of course.)
I agree. It's hard for me to describe the difference between ritalin and dex, but I'd say dex feels "warmer". I feel like a robot on ritalin, but dex makes me less irritable and more at ease, not just the improved focus.

I've found higher doses tend to make me like you describe -- excellent focus but I have to kind of make an effort to direct it properly. I like to sit at a mid-range dose, where I have improved focus, but not so strong that I feel like I have to kind of work to point it in the right direction.

Quote:
Originally Posted by Allison78 View Post
I am wondering what the average daily dose is? I'm at 40 now, and I think my doctor is going to be reluctant to go much higher, even though I wonder if I might benefit from it.
That sounds like a lot of dexamphetamine/dexedrine. I take 20 mg a day. The highest I've ever gone is 25 mg. In my country, my doctor tells me he has to get special authorisation to prescribe more than 30 mg a day. I don't think I'd ever sleep if I took 40 mg in one day!

Quote:
Originally Posted by Allison78 View Post
Also, I am shortly going to switch my AD from Zoloft to Effexor. Is it OK to take Dex and Effexor together? It almost seems like they'd help each other if Dex stimulates norepinephrine production (am I correct on that?) and Effexor inhibits the reuptake.
I can't comment on how effexor because I've had no experience with it. But drug interactions can be complex, it's hard to predict how they might interact.

I've been trying Edronax (a norepinephrine reuptake inhibitor) with my dex for a few weeks now. I had the same reasoning to think they might work well together, but I've had mixed results. The combination improves some things, such as sleep, motivation and anxiety, but I also feel a bit dopey and foggy. It's hard to describe exactly how it feels, but ultimately it seems to be weakening the main reason I take the dex -- focus and a kind of coordination of my thoughts (it's hard to describe... kind of putting things I do in the right order and being able to see a "bigger picture" for my actions). That's not to say that effexor won't work well with dex... just trying to illustrate the point that it can be hard to predict how drugs behave together.

I thought dex stimulated release of norepinephrine as well as inhibiting its reuptake a little, but didn't actually produce more of it. I could be mistaken though. Maybe someone else with more knowledge in this area can give you a better answer.
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Old 08-02-08, 02:45 AM
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Re: a handful of Dex questions

That sounds like a lot of dexamphetamine/dexedrine. I take 20 mg a day. The highest I've ever gone is 25 mg. In my country, my doctor tells me he has to get special authorisation to prescribe more than 30 mg a day. I don't think I'd ever sleep if I took 40 mg in one day!

In Australian Dexamphetamine and Ritalin can only be prescribed by a psychiatrist and that psychiatrist by law has to register the patient with governmental agencies. The maximum dosage for dex is 12 (60 mg) tablets per day and Ritalin is 6 (60 mg)tablets per day. No matter what your dose is; 25mg to 60 mg the psychdoc is required by law to register you. He/she does not need special permission to raise your dose to the maximum level.
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Old 08-02-08, 10:35 PM
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Re: a handful of Dex questions

I'm supposed to be taking 35 mg/day but usually I only take about 25.5.
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Old 08-03-08, 11:06 AM
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Re: a handful of Dex questions

The best dose is the one that both manages symptoms and is tolerated. Well read doctors up on research trends or specialist understand this. A doctor that says sorry we hit 40 mg and that's it needs to crack open a book.

IMO the best bet is a specialist. The fda 40 or 60 mg was set over 30/ 40 years ago for children. If it were to be changed or increased or whatever, a drug company would have to spend huge amounts of money to show the fda what everyone (fda, drs., drug company, etc.) already know-- stimulants can be tolerated at much higher doses than the 30+ year 60mg RECCOMENDED daily dose of the fda.

So drs. prescribe "off-label" and everyone is happy-- very common.

Google Dr. Joseph Biederman of Harvard, ADHD, etc. Great info
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Old 11-04-08, 12:31 AM
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Re: a handful of Dex questions

Quote:
Originally Posted by CaucusRace View Post
That sounds like a lot of dexamphetamine/dexedrine. I take 20 mg a day. The highest I've ever gone is 25 mg. In my country, my doctor tells me he has to get special authorisation to prescribe more than 30 mg a day. I don't think I'd ever sleep if I took 40 mg in one day!
Quote:
Originally Posted by strange&unusual View Post
In Australian Dexamphetamine and Ritalin can only be prescribed by a psychiatrist and that psychiatrist by law has to register the patient with governmental agencies. The maximum dosage for dex is 12 (60 mg) tablets per day and Ritalin is 6 (60 mg)tablets per day. No matter what your dose is; 25mg to 60 mg the psychdoc is required by law to register you. He/she does not need special permission to raise your dose to the maximum level.


(In Australia)
Daily doses in excess of 30mg dexamphetamine or 60mg methylphenidate or 75mg controlled release methylphenidate will require documented support from a second psychiatrist.


Last edited by Maddy; 11-04-08 at 12:33 AM.. Reason: added "In Australia"
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Old 01-24-09, 08:01 AM
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Re: a handful of Dex questions


Quote:
Originally Posted by Maddy View Post


(In Australia)
Daily doses in excess of 30mg dexamphetamine or 60mg methylphenidate or 75mg controlled release methylphenidate will require documented support from a second psychiatrist.

I think each of the jurisdictions in Australia have different requirements - I was required to get a second opinion from a psychiatrist to get a 6 month supply of Dex in Canberra but I could fill it at any chemist. Then when I moved to Sydney I found out that I had to refill my prescription at the same chemist each time.
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Old 01-24-09, 08:31 AM
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Re: a handful of Dex questions

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I think each of the jurisdictions in Australia have different requirements - I was required to get a second opinion from a psychiatrist to get a 6 month supply of Dex in Canberra but I could fill it at any chemist. Then when I moved to Sydney I found out that I had to refill my prescription at the same chemist each time.
In WA as far as I know, the max dex is 9 x 5mg daily, without special permission, or 6 x 5mg daily + 5 x 10mg ritalin daily, if you combine the two.
(that's what I get)
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Old 01-24-09, 06:17 PM
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Re: a handful of Dex questions

I am currently taking 40mg a day and my Psychiatrist has told me that I can increase my am dose by 5mg every couple of days until I see the most benefit without lots of side effects. He said I can even start 60mg a day eventually if I need to, but I haven't done that yet. His exact words about the future of my medication increases were, "You may be taking 20mg, 10mg, 10mg. Or you could try 30mg, 15mg, 15mg. You will see when it suits you. You will definitely know..." I am so glad I found a Psychiatrist who understands that one dose does not fit all. He is the first doctor I have seen that really wants me to feel my best, and he trusts me to find the right dose. And he said there really isn't a cap on the meds he will give me (of course to a physically safe limit!) because it depends on the severity of symptoms. For some 10mg a day is sufficient because that is the way their body works and that is great for *them*...and maybe their symptoms respond to that. But if you think 30mg may help more, you are entitled to try it.
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Old 01-27-09, 02:42 AM
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Re: a handful of Dex questions

I was on 20mg a day of the dex, even though they helped I wanted off them for the fact, being scottish living in australia is hot enough.Currently I'm on strattera 80mg.I find that will small amounts of dex seems to enhance my over all focus.My Psych like urs i find is pretty awesome will trying to figure out best line of treatment.One thing i have noticed is the fact that there is'nt too many options for treatment.Can't stand Long lasting form of ritalin/concerta.Instant release worked well but crash was horrible. anyone here onthe board that benifits from both strattera + Amphetamine? im not evensure if my doc is ok with the combination.

I take avanza at night 30mg and have no idea how that truly interacts with re-uptake ofthe strattera.Life is up and down at the moment and im not too sure bout staying here.I havent been able to see my doc in over a month.I'm been put on the anti-depressants and left to it.

Y is australia laggin behind?
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Old 01-27-09, 04:40 AM
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Re: a handful of Dex questions

Quote:
Originally Posted by CaucusRace View Post

That sounds like a lot of dexamphetamine/dexedrine. I take 20 mg a day. The highest I've ever gone is 25 mg. In my country, my doctor tells me he has to get special authorisation to prescribe more than 30 mg a day. I don't think I'd ever sleep if I took 40 mg in one day!
In America it seems the standard doses are higher for stimulants than here.

Effexor and Dex. usually are ok together, although in some people they can cause serotonin syndrome. I was on this combo and found the effexor made the dex last a bit longer but it also 'dampened' the effects so it didn't work as well.

Effexor isn't a drug i'd consider taking lightly. IT's the hardest anti-d style drug to stop IMO and the 'discontinuation syndrome' is horrible.

Straterra and amphetamine is fine for most people. Just introduce the new med. slowly, don't start at a high dose.
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