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  #1  
Old 02-11-14, 03:45 PM
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Racing Thoughts and Mood Stabilizers

Okay so was wondering,

*what* causes the racing thoughts to subside/slow down when it comes to a mood stabilizer being used to treat these symptoms and the condition?

Anyone know what the mood stabilizers mechanisms, neurotransmitter targets, any studies that show how the brain (bipolar) is affected/reacts to them etc.?

I am specifically interested in how mania(and hypomania) is affected by various mood stabilizers.

Any material or resources of sorts would be wonderful.

Thanks so much!!!!
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  #2  
Old 02-11-14, 04:07 PM
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Re: Racing Thoughts and Mood Stabilizers

thats a good question, most likely its unknown

one thing to consider, that each emotion ,( and I'm not positive which one(or more) is prevalent with racing thoughts ), has its own physiological correspondence

that may be something to consider

whats the blood pressure med that helps ADHD ?
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Old 02-11-14, 04:13 PM
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Re: Racing Thoughts and Mood Stabilizers

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Originally Posted by daveddd View Post
whats the blood pressure med that helps ADHD ?
Isn't it intuniv? Er, I think so, anyway.
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Old 02-11-14, 05:14 PM
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Re: Racing Thoughts and Mood Stabilizers

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Originally Posted by daveddd View Post
thats a good question, most likely its unknown

one thing to consider, that each emotion ,( and I'm not positive which one(or more) is prevalent with racing thoughts ), has its own physiological correspondence

that may be something to consider

whats the blood pressure med that helps ADHD ?
Thanks, yeah great points to consider

Thanks for mentioning

I shall ponder.

Hmmm I think Clonidine (and others)
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Old 02-11-14, 05:24 PM
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Re: Racing Thoughts and Mood Stabilizers

Intuniv I believe is long acting guanfacine, which is a little cleaner in terms of mechanism of action than clonidine. Both of them are alpha agonists and blood pressure meds. Good for hyperactivity, limited evidence of efficacy on memory, sketchy evidence for attentional benefit,
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Old 02-11-14, 05:42 PM
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Re: Racing Thoughts and Mood Stabilizers

There are some interesting things about Intuniv, it seems to combat anxiety in a number of ways. It reduces sympathetic arousal, weakens emotional responses of amygdala, and strengthens prefrontal cortical regulation of emotions. These same things naturally have the potential to improve attention span.
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Old 02-11-14, 06:06 PM
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Re: Racing Thoughts and Mood Stabilizers

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Originally Posted by MentalNomad View Post
There are some interesting things about Intuniv, it seems to combat anxiety in a number of ways. It reduces sympathetic arousal, weakens emotional responses of amygdala, and strengthens prefrontal cortical regulation of emotions. These same things naturally have the potential to improve attention span.
Ritalin dampens emotional reactivity in the amygdala as well

Part of the emotionally salient distraction theory

Correct me if I'm wrong I know very little about the physical

Concerta did calm racing thoughts for me until I became tolerant
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  #8  
Old 02-11-14, 06:08 PM
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Re: Racing Thoughts and Mood Stabilizers

I believe abilify also calms physiological arousal

It has in people with sensory issues
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Old 02-11-14, 07:05 PM
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Re: Racing Thoughts and Mood Stabilizers

Quote:
Originally Posted by daveddd View Post
Ritalin dampens emotional reactivity in the amygdala as well

Part of the emotionally salient distraction theory

Correct me if I'm wrong I know very little about the physical

Concerta did calm racing thoughts for me until I became tolerant
I doubt I'd be able to correct you, you seem to have a more general knowledge about this stuff than I do!

Concerta was a mixed bag for me, I don't seem to be able to tolerate stimulants very well.

Also, might seem like a basic question, but do stimulants strengthen prefrontal cortical activity? It's coming across to me that intuniv works in a more multi-faceted way than stimulants, but admittedly my knowledge of the latter is lacking.
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Old 02-11-14, 07:08 PM
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Re: Racing Thoughts and Mood Stabilizers

id ask tygersan
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Old 02-11-14, 07:09 PM
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Re: Racing Thoughts and Mood Stabilizers

in bipolar racing thoughts are generally seen in states of high arousal

i need to do some checkin
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Old 02-11-14, 07:41 PM
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Re: Racing Thoughts and Mood Stabilizers

what fits better for you bellavita
http://www.ncbi.nlm.nih.gov/pubmed/19515428
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Old 02-11-14, 07:47 PM
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Re: Racing Thoughts and Mood Stabilizers

Thanks, I'll check it out better after my rest

Appreciate the comments
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Old 02-11-14, 08:22 PM
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Re: Racing Thoughts and Mood Stabilizers

bellavita,

i know you have asked about psychobiology a few times

here are a few good pages on the psychobiology of bipolar for when your bored, came across it while trying to find what I'm looking for , for the thread


http://books.google.com/books?id=6bs...ipolar&f=false
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Old 02-11-14, 08:25 PM
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Re: Racing Thoughts and Mood Stabilizers

Quote:
Originally Posted by daveddd View Post
bellavita,

i know you have asked about psychobiology a few times

here are a few good pages on the psychobiology of bipolar for when your bored, came across it while trying to find what I'm looking for , for the thread


http://books.google.com/books?id=6bs...ipolar&f=false
Rest unsuccessful so far lol

Ooooooooo *squeal* thank you so much!!!!!!!!!!
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