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Old 11-27-03, 01:12 AM
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Salsa Salsa is offline
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Genetic Connections Between ADHD, Bipolar Disorder, Autism, Schizophrenia, Epilepsy +

Let me preface this by saying that I didn't copy and paste this off of a website. This is information that I have gathered on my own because of multiple psychological and neurological disorders in my immediate and extended family.


In my immediate family exists Classic Autism, Bipolar Disorder, Epilepsy, ADHD, Depression, and (possibly) Asperger Syndrome.

In my extended family is Pervasive Developmental Disorder/PDD-NOS, Anxiety Disorder, Lupus, Multiple Sclerosis, Drug & Alcohol Addiction, and Rheumatoid Arthritis. In addition there are more cases of ADHD, Bipolar Disorder and one other case of Autism.

For this reason, I have become very interested in Neuropsychology and Genetics. Because I think/am hoping that some of what I have found will be things that others might be able to find useful/interesting, I am wanting to share it on this forum. I have my information categorized by Chromosome Bands that the disorders are related to.

I mention numerous things but bolded ADHD, Autism and Bipolar Disorder.

Chromosome Band / Disorder or Disease

1q41-42 / Systemic lupus erythematosus
1q42-q43 / Bipolar Affective Disorder
1q42-q43 / Stroke/ High Blood Pressure
4p15 / Epilepsy, partial, w pericentral spikes
4p15.3-p16.1 / Bipolar
4p16-p15.2 / Systemic lupus erythematosus
6p21.3 / Rheumatoid arthritis [RA is an auto-immunity]
6p21.3 / Celiac Sprue (gluten intolerance)
[NOTE:] Gluten Sensitivity is common in ADHD, Autism and Epilepsy
6p21.3 / Ragweed Sensitivity (Allergies)
7q31.3-32.1 / Polycystic Ovary Syndrome
(I only included this because I have a half sister with PCOS)
7q31-35 / Autism
7q32-37° / Can incude Strabismus, long eyelashes
°Duplication of the long arm of chromosome 7
10q23.3-q24.1 / Partial Epilepsy
10q24 / Partial Epilepsy w. auditory features
10q24-q26 / ADHD (ADRA2 a2-adrenergic receptor)
10q24.3 / Polycystic Ovary Syndrome
(I only included this because I have a half sister with PCOS)
10q25.3-q26.1 / Epilepsy
10q26 / Bipolar Disorder (susceptibility)
10q26 / Schizophrenia
12q22-23 / Polycystic Ovary Syndrome
(I only included this because I have a half sister with PCOS)
12q24.1 / Leukemia, juvenile myelomonocytic
(My half sister again. Survived leukemia as a young child).
12q24.3 / Bipolar
12q24 / Predisposed to Autism
12q24 / Schizophrenia
12q24.2 / Alcohol intolerance
GABA-A receptor beta3 and alpha5 subunit gene cluster on chromosome band. Includes following disorder:

angelman ayndrome
autistic/asperger savant skills
bipolar disorder

15q13-14 / schizophrenia
15q13-14 / juvenile myoclonic epilepsy
16p13 / ADHD
16p13 / Epilepsy, myoclonic, infantile
16p13.3 / Systemic lupus erythematosus
16p13.3 / Bipolar Affective Disorder
16p13.3 / Tuberous Sclerosis 2*
*TSC2 can include:Epilepsy, Autism, and effect Mental Heath
19p13.1 / Celiac Disease (Gluten Intolerance)
19p13.1 / Generalized and Partial Epilepsy*
19p13.1 / Rheumatoid Arthritis (interleukin 12 receptor, beta 1)**
[RA is an auto-immunity]
22q11-q12 / Epilepsy, partial, with variable foci (2)
22q11.2 deletion Bipolar; Mixed State & Rapid Cycling
22q11.2 / Schizophrenia, susceptibility to
22q11-13 / Schizophrenia, susceptibility to
22q13.1 / Autism, succinylpurinemic
I have much more detail as to related disorders but many of them are rare and/or what seem to be unrelated disorders

Two Examples are:
10q24-q25 / Wolman Disease
16p13 / Osteopetrosis, recessive

I avoided listing them all. If I had, this would have been an extremely long post. I can email or PM info if anyone is wanting more information, but I posted what I believe might be most pertinent.


Last edited by Salsa; 11-27-03 at 02:07 AM..
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