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Dexedrine/Dextrostat (dextroamphetamine)

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  #1  
Old 04-16-12, 10:02 PM
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Exclamation Severe Depression when Dexedrine IR wears off.

I experience a very depressed state of mind when ever Dexedrine wears off (after 3.5 hours of positive effects).
The depression lasts a few hours, but it feels horrible.
I can't smile or think of anything happy. I don't feel like talking to anyone and people have commented on my frowning face.

That is the only side effect I get from Dexedrine. I don't feel anxious on it.

I'm usually a happy-go-lucky person.

I've tried Ritalin IR, but it gives me a lot more physical anxiety (feeling my heart pounding, feeling uncomfortable being in my own skin from the anxiety, etc).
The only thing is that Ritalin IR doesn't make me feel depressed when it wears off. I only feel overly anxious.

What can help? Any input is greatly appreciated.

By the way, I only take half of a 5mg tablet to a whole 5mg tablet per dose.
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I have= ADHD-PI, Panic Disorder, Generalized Anxiety Disorder, Depression, Social Phobia, Obsessive Compulsive Disorder, Mitral Valve Prolapse (heart condition), Internet Addiction..(self-diagnosed)

Rx= Nothing. Can't due to medical reasons.


Past Rx= Vyvanse 30mg (6/13/14), Adderall 15mg 1/7/14, Medical Marijuana, Smokeless Tobacco, Adderall IR 25mg 4/23/13, Dexedrine IR 20mg, Ritalin IR 60mg.

Last edited by Twiggy; 04-16-12 at 10:26 PM..
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Old 04-16-12, 10:22 PM
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Re: Severe Depression when Dexedrine IR wears off.

Perhaps you would be more helped by dex capsules......the extended release stuff .....

or, and I am flabberghasted that I am suggesting this , but if you have insurance it won't cost much at all ....and even if you pay out of pocket, you don't take a high dosage, ......


anyway, you might be better off with Vyvanse ....*cringe*...go and take a look in that su b-forum ......you can find out more about it there....

and look further in the dex sub-forum for info about the dex EX, caps.....

good luck ......
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  #3  
Old 04-16-12, 11:43 PM
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Re: Severe Depression when Dexedrine IR wears off.

Thanks Salleh. Is there anything else that could be done?
I'm trying to be on the least expensive medications possible, just in case if something happens to my insurance.
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I have= ADHD-PI, Panic Disorder, Generalized Anxiety Disorder, Depression, Social Phobia, Obsessive Compulsive Disorder, Mitral Valve Prolapse (heart condition), Internet Addiction..(self-diagnosed)

Rx= Nothing. Can't due to medical reasons.


Past Rx= Vyvanse 30mg (6/13/14), Adderall 15mg 1/7/14, Medical Marijuana, Smokeless Tobacco, Adderall IR 25mg 4/23/13, Dexedrine IR 20mg, Ritalin IR 60mg.
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Old 04-17-12, 05:03 AM
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Re: Severe Depression when Dexedrine IR wears off.

Quote:
Originally Posted by Twiggy View Post
I experience a very depressed state of mind when ever Dexedrine wears off (after 3.5 hours of positive effects).
The depression lasts a few hours, but it feels horrible.
This used to happen to me. The more I got used to dexamphetamine, the better the come down became. I still experience slight negativity when the dexamphetamine wears off that's no where near how intensely upset I used to get.

try lowering your dose (at least how much you have in one go) for a while and build up again slowly. It's all about getting your body to adjust to dexamphetamine while keeping the side effects to a minimum. You can keep your usual dose if while you adjust to it if you want, it's just that lowering the dose may lessen the come down effect while it's still a problem. Remember to take it consistently.

You can also try drinking/eating something very alkaline with your dexamphetamine. In my experience, doing this reduces side effects.

good luck.
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Old 06-04-12, 05:07 AM
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Re: Severe Depression when Dexedrine IR wears off.

Something that also helps me a lot is taking one more tablet and timing it so it will start working when (or a short period before) my initial dose starts wearing off. It will take practise to learn optimal timing.
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Old 06-04-12, 05:30 AM
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Re: Severe Depression when Dexedrine IR wears off.

avoid caffeine

Try and keep you blood sugar balanced (don't eat carbs by themselves - have some protein with it.)
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Old 06-04-12, 06:29 AM
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Re: Severe Depression when Dexedrine IR wears off.

Some people do much better ob dex spansules or an ir /xr combo. It could help with the crash.
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Old 07-08-18, 01:34 AM
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Re: Severe Depression when Dexedrine IR wears off.

I have the same thing - a listless period as it wears off. I'm thinking about taking my lexapro at lunch.
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Old 07-10-18, 01:31 PM
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Re: Severe Depression when Dexedrine IR wears off.

The reason you are feeling "depressed" when the Dexedrine IR stops working is actually from my research and based on my own experience quite normal especially in the beginning is because because Dexedrine contains Dextro Amphetamine which is more potent on Dopamine than its counterpart Levo Amphetamine.

So when you take Dexedrine your dopamine levels will raise and you will feel more focus, happiness, motivation, and you might even feel like a normal person with some kind of calm for the first time in your life. When the levels of Dextro Amphetamine gets under your threshold you will go back to "your own normal self" and this will make everything boring, you will feel sad.

Im not a doctor in any shape or form but I actually feel worse when I take a low dose of Dexedrine. Your dose is tiny for an adult or a teen. The normal starting dose your doctor should put you on should be 5mg 2-3 times per day for 1 week or so.

My point is you just have to look deep into yourself and see if you want to hang in there until you find YOUR CORRECT DOSAGE for YOUR BODY with YOUR METABOLISM etc, because trust me even if it feels like you want to give up, IT WILL GET BETTER. Or try to find an alternative medication or live your life without medication.

Sorry for the wall of text, my Dexedrine has worn of now rofl.

Hopefully I helped you somewhat.

It will get better, the side effects and crash will get less and less noticeable.

/Dear, Echo123.
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Old 10-29-18, 08:46 PM
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Re: Severe Depression when Dexedrine IR wears off.

You need to eat something and drink water, your appetite is suppressed but your body needs fuel from the excess work it had to do for the past 4 hours, there are no biological free lunches your body needs energy and it ends up feeling like depression instead of feelings of hunger. Make sure you are getting plenty of sleep as well.
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