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Old 11-27-03, 01:12 AM
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Genetic Connections Between ADHD, Bipolar Disorder, Autism, Schizophrenia, Epilepsy +

Let me preface this by saying that I didn't copy and paste this off of a website. This is information that I have gathered on my own because of multiple psychological and neurological disorders in my immediate and extended family.


In my immediate family exists Classic Autism, Bipolar Disorder, Epilepsy, ADHD, Depression, and (possibly) Asperger Syndrome.

In my extended family is Pervasive Developmental Disorder/PDD-NOS, Anxiety Disorder, Lupus, Multiple Sclerosis, Drug & Alcohol Addiction, and Rheumatoid Arthritis. In addition there are more cases of ADHD, Bipolar Disorder and one other case of Autism.

For this reason, I have become very interested in Neuropsychology and Genetics. Because I think/am hoping that some of what I have found will be things that others might be able to find useful/interesting, I am wanting to share it on this forum. I have my information categorized by Chromosome Bands that the disorders are related to.

I mention numerous things but bolded ADHD, Autism and Bipolar Disorder.

Chromosome Band / Disorder or Disease

1q41-42 / Systemic lupus erythematosus
1q42-q43 / Bipolar Affective Disorder
1q42-q43 / Stroke/ High Blood Pressure
4p15 / Epilepsy, partial, w pericentral spikes
4p15.3-p16.1 / Bipolar
4p16-p15.2 / Systemic lupus erythematosus
6p21.3 / Rheumatoid arthritis [RA is an auto-immunity]
6p21.3 / Celiac Sprue (gluten intolerance)
[NOTE:] Gluten Sensitivity is common in ADHD, Autism and Epilepsy
6p21.3 / Ragweed Sensitivity (Allergies)
7q31.3-32.1 / Polycystic Ovary Syndrome
(I only included this because I have a half sister with PCOS)
7q31-35 / Autism
7q32-37° / Can incude Strabismus, long eyelashes
°Duplication of the long arm of chromosome 7
10q23.3-q24.1 / Partial Epilepsy
10q24 / Partial Epilepsy w. auditory features
10q24-q26 / ADHD (ADRA2 a2-adrenergic receptor)
10q24.3 / Polycystic Ovary Syndrome
(I only included this because I have a half sister with PCOS)
10q25.3-q26.1 / Epilepsy
10q26 / Bipolar Disorder (susceptibility)
10q26 / Schizophrenia
12q22-23 / Polycystic Ovary Syndrome
(I only included this because I have a half sister with PCOS)
12q24.1 / Leukemia, juvenile myelomonocytic
(My half sister again. Survived leukemia as a young child).
12q24.3 / Bipolar
12q24 / Predisposed to Autism
12q24 / Schizophrenia
12q24.2 / Alcohol intolerance
GABA-A receptor beta3 and alpha5 subunit gene cluster on chromosome band. Includes following disorder:

angelman ayndrome
autistic/asperger savant skills
bipolar disorder

15q13-14 / schizophrenia
15q13-14 / juvenile myoclonic epilepsy
16p13 / ADHD
16p13 / Epilepsy, myoclonic, infantile
16p13.3 / Systemic lupus erythematosus
16p13.3 / Bipolar Affective Disorder
16p13.3 / Tuberous Sclerosis 2*
*TSC2 can include:Epilepsy, Autism, and effect Mental Heath
19p13.1 / Celiac Disease (Gluten Intolerance)
19p13.1 / Generalized and Partial Epilepsy*
19p13.1 / Rheumatoid Arthritis (interleukin 12 receptor, beta 1)**
[RA is an auto-immunity]
22q11-q12 / Epilepsy, partial, with variable foci (2)
22q11.2 deletion Bipolar; Mixed State & Rapid Cycling
22q11.2 / Schizophrenia, susceptibility to
22q11-13 / Schizophrenia, susceptibility to
22q13.1 / Autism, succinylpurinemic
I have much more detail as to related disorders but many of them are rare and/or what seem to be unrelated disorders

Two Examples are:
10q24-q25 / Wolman Disease
16p13 / Osteopetrosis, recessive

I avoided listing them all. If I had, this would have been an extremely long post. I can email or PM info if anyone is wanting more information, but I posted what I believe might be most pertinent.


Last edited by Salsa; 11-27-03 at 02:07 AM..
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Old 11-29-03, 09:55 AM
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Very interesting! I've read about the connections b/t many of these disorders, but have never seen the chromosomal arrangement laid out like this before. Even though this is your "abbreviated list," I see a number of disorders that run in my family ....
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Old 11-29-03, 10:35 AM
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Re: Genetic Connections Between ADHD, Bipolar Disorder, Autism, Schizophrenia, Epilepsy +

From your "list", these are the things that me or my immediate blood relatives have...

Originally posted by sandinmyears
Bipolar Disorder, ADHD, Depression, Anxiety Disorder, Drug & Alcohol Addiction/intolerance, Ragweed Sensitivity

Possible schizophrenia...
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Old 11-29-03, 11:08 AM
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Reading back, I notice that I need to clarify something. I was very sketchy on 7q32-37. This is referring to "Chromosome 7q duplication syndrome." Strabismus and Long Eyelashes are 2 features of this syndrome, however it is much more than these 2 features. "Chromosome 7q duplication syndrome" is a form of mental retardation. I never stated this. (Sorry about that). Sometimes my files are too abbreviated because I already know these things and forget to mention them when I post in public.

This syndrome especially interests me because my youngest dd, Elizabeth, (who has classic autism-- often associated with nearby chromosome band/s 7q31-35) is also severely/profoundly retarded. In addition, she has remarkably long eye lashes and was dx'd around the age of three with strabismus. (Which is why I had the notes about those two features/characteristics in my personal files). She is not dx'd with this syndrome, but because of the reasons mentioned above, I have done a little bit of reading up about it.

Here is a webpage with more about that syndrome:


P.S. This is the page I made for my daughter Elizabeth (who is autistic):
Those who matter don't mind.
Those who mind don't matter.

Last edited by Salsa; 11-29-03 at 11:25 AM..
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Old 12-20-03, 02:55 PM
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Interesting correlations

I would be interested in more of these correlations, Sandy, if you want to provide them. You can find my theory for the origin of autism (and many other psychiatric) conditions here:, The Neanderthal Theory.
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Old 12-20-03, 10:47 PM
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I've been to your site before when doing all my independent "research" (if you will).

Here are some other things I found and grouped together by chromosome bands that might relate to ADHD, Autism and/or Bipolar Disorder. When available, I list the "Gene Locus" between lines (like these "||").

Arrhythmogenic right ventricular dysplasia 2, 1q42.1-q43
Arrhythmogenic right ventricular dysplasia-2 1q42-q43
Bipolar Affective Disorder |AGT| 1q42-q43
Chediak-Higashi syndrome, |CHS1, LYST|1q42.1-q42.2
Diphenylhydantoin toxicity |EPHX1| 1q42.1
Familial Mediterranean Fever |MEF| 1q42-43
Fetal hydantoin syndrome |EPHX1| 1q42.1
Fumarase deficiency |FH| 1q42.1
Greenberg dysplasia, |LBR, PHA| 1q42.1
{Hypertension, essential, susceptibility to} |AGT, SERPINA8|1q42-q43
Hypoparathyroidism-retardation-dysmorphism syndrome, |TBCE, KCS, KCS1,HRD|1q42-q43
Kenny-Caffey syndrome-1 |TBCE, KCS, KCS1, HRD| 1q42-q43
Left-right axis malformation |EBAF, TGFB4, LEFTY1|1q42.1
Leiomyomatosis and renal cell cancer, |FH| 1q42.1
Longevity |ADPRT| 1q41-q42
Multiple cutaneous and uterine leiomyomata, |FH|1q42.1
Muscular dystrophy, congenital, 1B |MDC1B| 1q42
Myopathy, actin |ACTA1, ASMA, NEM2, NEM1| 1q42.1
Myopathy, nemaline, |ACTA1, ASMA, NEM2, NEM1|1q42.1
Pelger-Huet anomaly, 169400 (3) |LBR, PHA| 1q42.1
{Preeclampsia, susceptibility to} |AGT, SERPINA8| 1q42-q43
{Prostate cancer, susceptibility to}, |PCAP, PRCA2|1q42.2-q43
Retinitis pigmentasa, AR, without hearing loss,|USH2A|1q41
Schizophrenia, |DISC1|1q42.1
Schizophrenia, |DISC2|1q42.1
Stroke/ High Blood Pressure |AGT|1q42-q43
Systemic lupus erythematosus|SLEB1, SLE1|1q41-42
Ventricular tachycardia, stress-induced polymorphic, |RYR2, VTSIP|1q42.1-q43
Xeroderma pigmentosum|ADPRT, PPOL|1q42

3q21q26 syndrome|EVI1|3q26
3-Methylcrotonylglycinuria I |MCCC1, MCCA|3q25-q27
ADULT syndrome, |TP73L, TP63, KET, EEC3, SHFM4, LMS|3q27
Abdominal obesity-metabolic syndrome |AOMS1, SYNX|3q27
Anophthalmia|SOX2, ANOP3|3q26.3-q27
Apnea, postanesthetic |BCHE, CHE1|3q26.1-q26.2
{Autism, susceptibility to, 3} |AUTS3|3q25-q27
[Blood group, P system], |B3GALT3, GLCT3, P|3q25
Cerebral cavernous malformations-3 |CCM3|3q25.2-q27
Cornelia de Lange syndrome |CDL1|3q26.3
Congenital disorder of glycosylation, type Id |ALG3, NOT56L, CDGS4|3q27
{Diabetes mellitus, noninsulin-dependent} |SLC2A2, GLUT2|3q26.1-3q26.3
Ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 3,|TP73L, TP63, KET, EEC3, SHFM4, LMS|3q27
Encephalopathy, familial, with neuroserpin inclusion bodies, |SERPINI1, PI12|3q26
Epilepsy with grand mal seizures on awakening, |CLCN2, EGMA, ECA3|3q26-qter
Epilepsy, childhood absence|CLCN2, EGMA, ECA3|3q26-qter
{Epilepsy, idiopathic generalized, susceptibility to},|EGI3|3q26.1
Epilepsy, juvenile absence |CLCN2, EGMA, ECA3|3q26-qter
Epilepsy, juvenile myoclonic |CLCN2, EGMA, ECA3|3q26-qter
Fanconi-Bickel syndrome|SLC2A2, GLUT2|3q26.1-q26.3
Goiter, multinodular,|MNG3|3q26.1-q26.3
Hay-Wells syndrome|TP73L, TP63, KET, EEC3, SHFM4, LMS|3q27
Hypomagnesemia, primary |CLDN16, PCLN1|603959|3q27
Ichthyosis, leukocyte vacuoles, alopecia, and sclerosing cholangitisILVASC|3q27-q28
[Kininogen deficiency]|KNG|3q27
Leukemia, myeloid, acute|MLF1|3q25.1
Leukoencephalopathy with vanishing white matter|EIF2B5, LVWM, CACH, CLE|3q27
Limb-mammary syndrome|TP73L, TP63, KET, EEC3, SHFM4, LMS|3q27
Lymphoma, B-cell|BCL6|3q27
Myelodysplasia syndrome-1 |MDS1|3q26
Ovarian cancer |PIK3CA|3q26.3
Spastic paraplegia 14, autosomal recessive|SPG14|3q27-q28
Split-hand/foot malformation, type 4, |TP73L, TP63, KET, EEC3, SHFM4, LMS|3q27
Sucrose intolerance |SI| 3q25-q26
Thrombocythemia, essential |THPO, MGDF, MPLLG, TPO|3q26.3q27
Thrombophilia due to HRG deficiency (3) |HRG|3q27

Achondroplasia |FGFR3, ACH|4p16.3
Bipolar 4p15.3-p16.1
Bladder cancer, |FGFR3, ACH|4p16.3
{Blepharospasm, primary benign |DRD5, DRD1B, DRD1L2|4p16.1-p15.3
Cervical cancer, somatic, |FGFR3, ACH|4p16.3
Cherubism, |SH3BP2, CRPM|4p16.3
Colorectal cancer, somatic, |FGFR3, ACH|4p16.3
{Congestive heart failure, susceptibility to} |ADRA2C, ADRA2L2|4p16.1
Craniosynostosis, Adelaide type |CRSA, CRS3|4p16
Crouzon syndrome with acanthosis nigricans |FGFR3, ACH|4p16.3
Dystonia, primary cervical |DRD5, DRD1B, DRD1L2|4p16.1-p15.3
Ellis-van Creveld syndrome, |EVC|4p16
Ellis-van Creveld syndrome, |LBN, EVC2|4p16
Epilepsy, partial, with pericentral spikes |EPPS|4p15
Hearing loss, low-frequency sensorineural, |WFS1, WFRS, WFS, DFNA6|4p16.1
Huntington disease-like 3 |HDL3, HLN2|4p15.3
Huntington disease |HD, IT15|4p16.3
{Hypertension, essential, salt-sensitive} |ADD1|4p16.3
Hypochondroplasia, 146000 |FGFR3, ACH|4p16.3
Hypodontia with orofacial cleft, |MSX1, HOX7, HYD1|4p16.1
Hypodontia, autosomal dominant, |MSX1, HOX7, HYD1|4p16.1
Lipodystrophy, familial partial, with decreased subcutaneous fat of face and neck |PPARGC1|4p15.1
Macular dystrophy 2, Bull's eye |MCDR2|4p16.3-p15.2
Mucopolysaccharidosis Ih|IDUA, IDA|4p16.3
Mucopolysaccharidosis Ih/s|IDUA, IDA|4p16.3
Mucopolysaccharidosis Is|IDUA, IDA|4p16.3
Muencke syndrome|FGFR3, ACH|4p16.3
Night blindness, congenital stationary, type 3|PDE6B, PDEB, CSNB3|4p16.3
{Nasopharyngeal carcinoma 1 |NPC1, NPCA1|4p15.1-q12
Parkinson disease 4, autosomal dominant, Lewy body |PARK4|4p15
Phenylketonuria due to dihydropteridine reductase deficiency|QDPR, DHPR|4p15.31
Retinal degeneration, autosomal recessive, prominin-related|PROM1, PROML1, AC133|4p16.2-p12
Retinitis pigmentosa, autosomal recessive|PDE6B, PDEB, CSNB3|4p16.3
{Systemic lupus erythematosus, susceptibility to, 3}|SLEB3|4p16-p15.2
Thanatophoric dysplasia, types I and II,|FGFR3, ACH|4p16.3
Weyers acrodental dysostosis |EVC|4p16
Witkop syndrome |MSX1, HOX7, HYD1| 4p16.1
Wolf-Hirschhorn syndrome|WHCR| 4p16.3
Wolfram syndrome, |WFS1, WFRS, WFS, DFNA6|4p16.1

Autism-like syndrome |AUTS2, KIAA0442|7q11.2
Autism |7q31-35
Basal cell carcinoma, sporadic|SMOH, SMO|7q31-q32
[Body mass index] |BMIQ1|7q32.3
Colorblindness, tritan|OPN1SW, BCP, CBT|7q31.3-q32
Congenital bilateral absence of vas deferens |CFTR, ABCC7, CF, MRP7|7q31.2
Cutis laxa, marfanoid neonatal type|LAMB1|7q31.1-q31.3
Cystic fibrosis|CFTR, ABCC7, CF, MRP7|7q31.2
Deafness, autosomal recessive 14 |DFNB14|7q31
Deafness, autosomal recessive 17 |DFNB17|7q31
Deafness, autosomal recessive 4 |SLC26A4, PDS, DFNB4|7q31
Enlarged vestibular aqueduct |SLC26A4, PDS, DFNB4|7q31
{H. pylori infection, susceptibility to} |PTPRZ1, PTP18|7q31.3
Hemolytic anemia due to bisphosphoglycerate mutase deficiency |BPGM|7q31-q34
Hepatocellular carcinoma, childhood type |MET|7q31
{Hypertrypsinemia, neonatal}|CFTR, ABCC7, CF, MRP7|7q31.2
Lipoamide dehydrogenase deficiency |DLD, LAD, PHE3|7q31-q32
Obesity, morbid, with hypogonadism |LEP, OB|7q31.3
Obesity, severe, due to leptin deficiency |LEP, OB|7q31.3
{Pancreatitis, idiopathic} |CFTR, ABCC7, CF, MRP7|7q31.2
Pendred syndrome |SLC26A4, PDS, DFNB4|7q31
PCOS (Polycystic ovary syndrome) |OB |7q31.3-32.1
Renal cell carcinoma, papillary, familial and sporadic |MET| 7q31
Retinitis pigmentosa-10 |RP10| 7q31-q35
Retinitis pigmentosa-10 |IMPDH1| 7q31.3-q32
Saccharopinuria |AASS| 7q31.3
Speech-language disorder-1 |FOXP2, SPCH1, TNRC10, CAGH44|605317|7q31
Stature QTL 7 |STQTL7|7q31.3
Strabismus |7q32-37 (Duplication of the long arm of chromosome 7)
Sweat chloride elevation without CF |CFTR, ABCC7, CF, MRP7|7q31.2

ADHD |ADRA2 a2-adrenergic receptor |10q24-q26
Adrenal hyperplasia, congenital, due to 17-alpha-hydroxylase deficiency |CYP17A1, CYP17, P450C17|10q24.3
Alzheimer disease 6|AD6|10q24
Anterior segment mesenchymal dysgenesis and cataract |PITX3|10q25
Antley-Bixler syndrome |FGFR2, BEK, CFD1, JWS| 10q26
Apert syndrome |FGFR2, BEK, CFD1, JWS|10q26
{Autoimmune lymphoproliferative syndrome} |TNFRSF6, APT1, FAS, CD95|10q24.1
Bannayan-Riley-Ruvalcaba syndrome |PTEN, MMAC1|10q23.31
Bannayan-Zonana syndrome |PTEN, MMAC1| 10q23.31
Beare-Stevenson cutis gyrata syndrome |FGFR2, BEK, CFD1, JWS| 10q26
Bipolar Disorder (susceptibility) |10q26
Carboxypeptidase N deficiency |CPN1, SCPN, CPN|10q24.2
Cardiomyopathy, hypertrophic, early-onset fatal |COX15| 10q24
Cataract, congenital |PITX3|10q25
Charcot-Marie-Tooth disease, dominant intermediate 2 |CMTDI2|10q24.1-q25.1
Cholesteryl ester storage disease |LIPA|10q24-q25
{congestive heart failure, susceptibility to} |ADRB1, ADRB1R, RHR| 10q24-q26
Corneal dystrophy, Thiel-Behnke type |CDB2, CDTB|10q24
Cowden disease, 158350 (3) |PTEN, MMAC1|601728|10q23.31
Craniofacial-skeletal-dermatologic dysplasia |FGFR2, BEK, CFD1, JWS|10q26
Craniosynostosis, nonspecific |FGFR2, BEK, CFD1, JWS|10q26
Crouzon syndrome |FGFR2, BEK, CFD1, JWS|10q26
{Diabetes mellitus, insulin-dependent, 17} |IDDM17|10q25
Dubin-Johnson syndrome, |ABCC2, CMOAT|10q24
Endometrial carcinoma|PTEN, MMAC1|10q23.31
Endometrial carcinoma (2) |DEC|10q26
Epidermolysis bullosa, generalized atrophic benign, |COL17A1, BPAG2|10q24.3
Epilepsy, partial, with auditory features, |LGI1, EPT|10q24
Gastric cancer, somatic,|FGFR2, BEK, CFD1, JWS|10q26
Glioblastoma |WDR11, DR11, KIAA1351|10q26
Glioblastoma multiforme, somatic |DMBT1| 10q25.3-q26.1
Glioblastoma, somatic |LGI1, EPT| 10q24
Gyrate atrophy of choroid and retina with ornithinemia, B6 responsive or unresponsive |OAT|10q26
Hermansky-Pudlak syndrome|HPS1|10q23.1
Hermansky-Pudlak syndrome|HPS6, RU|10q24.32
Hyperinsulinism-hyperammonemia syndrome|GLUD1|10q23.3
Hypoglobulinemia and absent B cells |BLNK, SLP65| 10q23.2
Jackson-Weiss syndrome |FGFR2, BEK, CFD1, JWS|10q26
Leukemia, T-cell acute lymphocytic |TLX1, HOX11, TCL3|10q24
Lhermitte-Duclos syndrome |PTEN, MMAC1|10q23.31
Medulloblastoma |DMBT1| 10q25.3-q26.1
Medulloblastoma |PEO1, PEO|10q24
Medulloblastoma, desmoplastic|SUFU, SUFUXL, SUFUH|10q24-q25
Meningioma, 156100 (3) |PTEN, MMAC1|10q23.31
Mephenytoin poor metabolizer |CYP2C, CYP2C19|10q24.1-q24.3
Neurofibrosarcoma |MXI1|10q25
Neuropathy, motor and sensory, Russe type |NMSR, HMSNR|10q23.2
Oligodendroglioma |PTEN, MMAC1| 10q23.31
Optic nerve coloboma with renal disease |PAX2| 10q24.3-q25.1
P5CS deficiency |PYCS, GSAS| 10q24.3
Pancreatic lipase deficiency |PNLIP| 10q26.1
Pfeiffer syndrome |FGFR2, BEK, CFD1, JWS| 10q26
Porphyria, congenital erythropoietic |UROS|606938|10q25.2-q26.3
Progressive external ophthalmoplegia with mitochondrial DNA deletions,|C10orf2, TWINKLE, PEO1, PEO| 10q24
{Prostate cancer}, |PTEN, MMAC1|10q23.31
{Prostate cancer, susceptibility to}, |MXI1|10q25
Proteus syndr |PTEN, MMAC1|10q23.31
Renal hypoplasia, isolated |PAX2|10q24.3-q25.1
[Resting heart rate] |ADRB1, ADRB1R, RHR|10q24-q26
Retinitis pigmentosa, autosomal dominant|RGR|10q23
Retinitis pigmentosa, autosomal recessive|RGR|10q23
Retinol binding protein, deficiency of |RBP4|10q24
Saethre-Chotzen syndrome|FGFR2, BEK, CFD1, JWS|10q26
Spastic paraplegia-9 |SPG9|10q23.3-q24.1
Spinocerebellar ataxia, infantile-onset, with sensory neuropathy |IOSCA, SCA8|10q24
Split hand/foot malformation, type 3 |SHFM3, DAC |10q24
Squamous cell carcinoma, burn scar-related, somatic |TNFRSF6, APT1, FAS, CD95|10q24.1
Thyroid carcinoma, follicular, |PTEN, MMAC1| 10q23.31
Tolbutamide poor metabolizer|CYP2C9|10q24
Urofacial syndrome|UFS|10q23-q24
VATER association with hydrocephalus|PTEN, MMAC1|10q23.31
Warfarin sensitivity, |CYP2C9|10q24
Wolman disease |LIPA|10q24-q25

Acyl-CoA dehydrogenase, short-chain, deficiency of |ACADS, SCAD|12q22-qter
Alcohol intolerance, acute |ALDH2|12q24.2
B-cell non-Hodgkin lymphoma, high-grade |BCL7A, BCL7|12q24.1
Bipolar Disorder |P2RX7, P2X7| 12q24.3
Cornea plana congenita, recessive, 217300 (3) |KERA, CNA2|603288|12q22
Diabetes mellitus, noninsulin-dependent, 2 (2) |NIDDM2|601407|12q24.2
Growth retardation with deafness and mental retardation (3) |IGF1|147440|12q22- q24.1
Hepatic adenoma, 142330 (3) |TCF1, HNF1A, MODY3|142410|12q24.2
[Histidinemia] (1) |HAL, HSTD|235800|12q22-q23
Holt-Oram syndrome, 142900 (3) |TBX5|601620|12q24.1
Hyper-IgD syndrome, 260920 (3) |MVK, MVLK|251170|12q24
Leopard syndrome, 151100 (3) |PTPN11, PTP2C, SHP2, NS1|176876|12q24.1
Leukemia, chronic lymphatic |P2RX7, P2X7| 12q24
Male germ cell tumor (2) |MGCT|273300|12q22
Methylmalonic aciduria, vitamin B12-responsive, due to defect in synthesis of adenosylcobalamin, cblB complementation type, 251110 (3) |MMAB|607568|12q24
MODY, type III, 600496 (3) |TCF1, HNF1A, MODY3|142410|12q24.2
Leukemia, juvenile myelomonocytic, 607785 (3) |PTPN11, PTP2C, SHP2, NS1|176876|12q24.1
PCOS (Polycystic Ovarian Syndrome) |12q22-23
Predisposed to Autism |Reelin| 12q24
Schizophrenia |DAO, DAMOX| 12q24

{Asthma} |PHF11, NYREN34|13q14.1
{Autism, susceptibility to, 4} |AUTS4|13q14.2-q14.1
Bare lymphocyte syndrome, type II, complementation group D |RFXAP|13q14
Bladder cancer|RB1|13q14.1-q14.2
[Body mass index] |BMIQ2|13q14
Dementia, familial British |ITM2B, BRI, ABRI, FBD|13q14
Dementia, familial Danish |ITM2B, BRI, ABRI, FBD|13q14
Gastroesophageal reflux |GER| 13q14
Hyperornithinemia-hyperammonemia-homocitrullinemia syndrome |SLC25A15, ORNT1, HHH|13q14
[IgE levels QTL]|PHF11, NYREN34|13q14.1
Leukemia, chronic lymphocytic, B-cell|D13S25, DBM|13q14
{Nonsmall cell lung cancer}|DDX26, DICE1|13q14.12-q14.2
Pinealoma with bilateral retinoblastoma|RB1|13q14.1-q14.2
Retinoblastoma |RB1|13q14.1-q14.2
Rhabdomyosarcoma, alveolar|FOXO1A, FKHR|13q14.1
Rieger syndrome, type 2 |RIEG2, RGS2|13q14
Spastic paraplegia 24 |SPG24|13q14
Wilson disease|ATP7B, WND|13q14.3-q21.1

AGAT deficiency |GATM, AGAT|15q15.3
Adiponectin deficiency |APM1, GBP28|3q27
Agenesis of the corpus callosum with peripheral neuropathy |SLC12A6, KCC3A, KCC3B, KCC3, ACCPN|15q13-q14
Albinism, brown oculocutaneous|OCA2, P, PED, D15S12, BOCA|15q11.2-q12
Albinism, ocular, autosomal recessive |OCA2, P, PED, D15S12, BOCA| 15q11.2-q12
Albinism, oculocutaneous, type II |OCA2, P, PED, D15S12, BOCA|15q11.2-q12
Albright hereditary osteodystrophy-2 |AHO2|15q11-q13
Angelman syndrome |UBE3A, ANCR|15q11-q13
{Autism, susceptibility to} |AUTS1, AUT|15q11-q13
GABA-A receptor beta3 and alpha5 subunit gene cluster on chromosome15q11-q13
angelman syndrome (Elizabeth's facial features)
autistic/asperger savant
{Gluten-sensitive enteropathy, susceptibility to}|GSES|15q11-q13
{Hypertriglyceridemia, susceptibility to} |HTGS|15q11.2-q13.1
Juvenile Myoclonic Epilepsy |CHRNA7| 15q13-14
Lymphoma, diffuse large cell|BCL8|15q11-q13
Nanophthalmos 2|NNO2|15q12-q15
Prader-Willi syndrome |PWCR, PWS|15q11
Prader-Willi syndrome |NDN|15q11-q13
Prader-Willi syndrome |SNRPN|15q12
Schizophrenia |CHRNA7| 15q13-14
Spastic paraplegia-6 |SPG6|15q11.1
Spastic paraplegia-11 |SPG11|15q13-q15
[Eye color, brown] |EYCL3|15q11-q15
[Hair color, brown] |HCL3|15q11-q15

Attention deficit-hyperactivity disorder|ADHD|16p13
Bipolar Affective Disorder |SSTR5| 16p13.3
Carbohydrate-deficient glycoprotein syndrome, type I, |PMM2, CDG1|16p13.3-p13.2
Cataract, congenital, with microphthalmia |CATM|16p13.3
Charcot-Marie-Tooth disease, type 1C |LITAF, CMT1C| 16p13.3-p12
Deafness, autosomal dominant 40 |CRYM, DFNA40|16p13.11-p12.3
Epilepsy, myoclonic, infantile |EIM |16p13
Familial Mediterranean fever |MEFV, MEF, FMF|16p13
GABA-transaminase deficiency |ABAT, GABAT|16p13.3
[Glyoxalase II deficiency] |HAGH, GLO2|16p13
Hepatocellular carcinoma |AXIN1, AXIN|16p13.3
{?Hypertension, essential} |SAH| 16p13.11
Liddle syndrome, 177200 |SCNN1B|16p13-p12
Liddle syndrome, 177200 |SCNN1G, PHA1|16p13-p12
Lymphangioleiomyomatosis, somatic |TSC2, LAM| 16p13.3
MHC class II deficiency, complementation group A |MHC2TA, C2TA| 16p13
Microhydranencephaly |MHAC|16p13.3-p12.1
Osteopetrosis, autosomal dominant, type II |CLCN7, CLC7, OPTA2|16p13
Osteopetrosis, recessive |CLCN7, CLC7, OPTA2|16p13
PKDTS, infantile severe, with tuberous sclerosis |PKD|16p13.3
Polycystic kidney disease, adult type I |PKD1|601313|16p13.3-p13.12
Polycystic kidney disease, infantile severe, with tuberous sclerosis|PKDTS|16p13.3
Pseudohypoaldosteronism, type I |SCNN1B|16p13-p12
Pseudohypoaldosteronism, type I |SCNN1G, PHA1|16p13-p12
Pseudoxanthoma elasticum, autosomal dominant |ABCC6, ARA, ABC34, MLP1, PXE|16p13.1
Pseudoxanthoma elasticum, autosomal recessive |ABCC6, ARA, ABC34, MLP1, PXE|16p13.1PXE|16p13.1
Rubenstein-Taybi syndrome |CREBBP, CBP, RSTS|16p13.3
Systemic lupus erythematosus |SLE|16p13.3
Tuberous sclerosis-2 |TSC2, LAM|16p13.3
TSC2 can include:Epilepsy, Autism, Rosacea, Renal & Cardiac Problems
Xeroderma pigmentosum, group F|ERCC4, XPF|16p13.3-p13.13

Adenylosuccinase deficiency |ADSL|22q13.1
Agammaglobulinemia, autosomal recessive |IGLL1, IGO, 5 |22q11.21
{Amyotrophic lateral sclerosis, susceptibility to} |NEFH|22q12.2
Autism, succinylpurinemic |ADSL|22q13.1
Bernard-Soulier syndrome, type B |GP1BB|22q11.2
[Blood group, P system] |A4GALT, PK|22q13.2
{Breast and colorectal cancer, susceptibility to} |CHEK2, RAD53, CHK2, CDS1| 22q12.1
{Breast cancer, susceptibility to} |CHEK2, RAD53, CHK2, CDS1| 22q12.1
Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency |SCO2| 22q13
Cat eye syndrome |CECR, CES| 22q11
Cataract, cerulean, type 2 |CRYBB2, CRYB2| 22q11.2-q12.2
Cataract, cerulean, type 2 |CRYB2| 22q11.2-q12.2
Chondrosarcoma, extraskeletal myxoid|EWSR1, EWS| 22q12
Chromosome 22q13.3 deletion syndrome |PSAP2, PROSAP2, KIAA1650|22q13.3
Colorectal cancer |EP300| 22q13
Conotruncal cardiac anomalies |CTHM| 22q11
Costello syndrome |CTLO|22q13.1
Deafness, autosomal dominant 17, |MYH9, MHA, FTNS, DFNA17|22q11.2
Debrisoquine sensitivity |CYP2D@, CYP2D, P450C2D|22q13.1
Dermatofibrosarcoma protuberans |PDGFB, SIS| 22q12.3-q13.1
DiGeorge syndrome |DGCR, DGS, VCF|22q11
Epilepsy, partial, with variable foci |FPEVF|22q11-q12
Epstein syndrome |MYH9, MHA, FTNS, DFNA17| 22q11.2
Ewing sarcoma |EWSR1, EWS|22q12
Fechtner syndrome,|MYH9, MHA, FTNS, DFNA17|22q11.2
[Gamma-glutamyltransferase, familial high serum]|GGT2|22q11.1
Giant platelet disorder, isolated |GP1BB|22q11.2
Giant-cell fibroblastoma |PDGFB, SIS|22q12.3-q13.1
Glucose/galactose malabsorption|SLC5A1, SGLT1|22q13.1
Glutathioninuria|GGT1, GTG|22q11.1-q11.2
Heme oxygenase-1 deficiency |HMOX1|22q12
Heparin cofactor 2 deficiency |SERPIND1|22q11
Hermansky-Pudlak syndrome|HPS4|22q11.2-q12.2
Hyperprolinemia, type I|PRODH, PRODH2|22q11.2
Insulinoma |ITS|22q12.1-q12.2
Kanzaki disease|NAGA|22q11
Leukemia, chronic myeloid (3), Leukemia, acute lymphocytic|BCR, CML, PHL, ALL|22q11.21
Li-Fraumeni syndrome|CHEK2, RAD53, CHK2, CDS1|22q12.1
Male infertility due to acrosin deficiency|ACR|22q13-qter
May-Hegglin anomaly |MYH9, MHA, FTNS, DFNA17| 22q11.2
Megakaryoblastic leukemia, acute |MKL1, AMKL, MAL| 22q13
Megalencephalic leukoencephalopathy with subcortical cysts |MLC1, LVM, VL| 22qter
Meningioma|MN1, MGCR|22q12.3-qter
Meningioma, NF2-related, somatic|NF2|22q12.2
Meningioma, SIS-related |PDGFB, SIS|22q12.3-q13.1
Metachromatic leukodystrophy |ARSA|22q13.31-qter
Methemoglobinemia, type I |DIA1|22q13.31-qter
Methemoglobinemia, type II |DIA1|22q13.31-qter
Myoneurogastrointestinal encephalomyopathy syndrome|ECGF1|22q13.32-qter
NAGA deficiency, mild |NAGA|22q11
Neuroepithelioma |EWSR1, EWS|22q12
Neurofibromatosis, type 2,|NF2|22q12.2
Neutrophil immunodeficiency syndrome |RAC2|22q12.3-q13.2
Opitz G syndrome, type II |OGS2, BBBG2, GBBB2|22q11.2
Osteosarcoma, somatic, |CHEK2, RAD53, CHK2, CDS1|22q12.1
{?Parkinsonism, susceptibility to} |CYP2D@, CYP2D, P450C2D|22q13.1
Prostate cancer, familial |CHEK2, RAD53, CHK2, CDS1|22q12.1
Pulmonary alveolar proteinosis|CSF2RB|22q12.2-q13.1
Rhabdoid predisposition syndrome, familial|SMARCB1, SNF5, INI1, RDT|22q11
Rhabdoid tumors |SMARCB1, SNF5, INI1, RDT|22q11
Schindler disease |NAGA|22q11
{?Schizophrenia, susceptibility to} |PRODH, PRODH2|22q11.2
{?Schizophrenia}, |APOL1|22q12.3
{Schizophrenia, susceptibility to} |COMT|22q11.2
{Schizophrenia} |APOL2|22q12.3
{Schizophrenia} |APOL4|22q12.3
{Schizophrenia} |SCZD4|22q11-q13
Schwannomatosis |NF2|22q12.2
Sebastian syndrome |MYH9, MHA, FTNS, DFNA17|22q11.2
Sorsby fundus dystrophy |TIMP3, SFD|22q12.1-q13.2
Spinocerebellar ataxia-10 |SCA10|22q13
Transcobalamin II deficiency |TCN2, TC2|22q11.2-qter
Velocardiofacial syndrome, |DGCR, DGS, VCF|22q11
Waardenburg-Shah syndrome, |SOX10, WS4|22q13
Waardenburg-Shah syndrome, neurologic variant |SOX10, WS4|22q13
Yemenite deaf-blind hypopigmentation syndrome |SOX10, WS4|22q13
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Old 12-21-03, 02:11 AM
Wheel1975 Wheel1975 is offline

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Where are you getting your source data for genetic markers, bands and locations. I'm interested!
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Old 12-21-03, 07:28 AM
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Here are my main sources:

I'm sad to say that the source I used most often (my best source) no longer pulls up:

The first 2 links probably have the most information. I put "research" in quotation marks up above because the information was already there, I just grouped it a little bit differently to fit my needs. Looking for "common denominators" in disorders such as Epilepsy (self, cousin, great-aunt), Bipolar Disorder (self, aunt, ?brother), ADHD (self, daughters, many others), Autism (daughter, nephews), Lupus (my aunt), Fetal Hydantoin Syndrome (my youngest daughter), Asperger Syndrome (probably my oldest daughter), Chronic Fatigue Syndrome (my aunt), Familial Mediterranean Fever (distant cousin), and Rheumatoid Arthritis (my grandmother). I found the similarities in these chromosome bands.

If you want to read up more on this, go to GOOGLE and type in "Human Genome Mapping " or "Human Chromosome Map."

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Last edited by Salsa; 12-21-03 at 08:15 AM..
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Old 12-21-03, 12:12 PM
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Fascinating, Sandy. I'm a genetics geek too! You've given me a lot to think about.
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Old 02-17-04, 10:30 AM
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My daughter saw a geneticist 2 weeks ago. No results yet. One of his focuses was on chromosome band #15.

I don't know why I didn't see this before but on my long list under #15 is:

{Gluten-sensitive enteropathy, susceptibility to}|GSES|15q11-q13

I, myself, am on a gluten free diet and I'm trying to get the home where my daughter (who is autistic and mentally retarded) lives to put her back on a gluten-free casein-free diet. (They're actually considering putting the entire home on the diet, but it's taking them a long time to do it).

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Old 02-17-04, 12:04 PM
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While I don't understand alot of the information you presented I too see alot of links were it all applies to my own family and it is definatly interesting and something worth looking into.

Also, I went to Elizabeth's webpage and she is absolutly beautiful and I don't think God could have chosen a better mother for her. Your kindness, thoughtfullness and deep love for your little girl are evident. Keep the faith and stay strong.

Many good wishes to you and your's,
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Old 05-03-04, 10:22 AM
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A bit OT but not really, if you look up a few posts:

Wanted to mention that the group home where my youngest daughter lives has got her on a gfcf (gluten-free casein-free) diet again. I say "again" because I had her on the diet when she lived at home.

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Old 05-03-04, 11:08 AM
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TY for the excellent post. If you havent already, please checkout the US Surgeon General's Report on Mental Health,Chapter 3Disorders of Infancy,Children and Adolescents). In it you will find the reference for the landmark study on determining the ADHD gene marker (,1995).Fascinating article(if you like this kind of stuff, which I do too).

Keep up the good work and thank you again for sharing the results of your investigations.
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Old 05-03-04, 11:09 AM
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lol...sorry for the If for some reason you have trouble finding that info, Id be glad to get more info.
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Old 05-03-04, 12:51 PM
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