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Old 07-02-08, 06:38 PM
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Bayashi Bayashi is offline

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Question ADHD Medication & Sertraline (Zoloft) & Mirtazapine (Remeron)

Just started taking the Mirtazapine in addition to Methylphenidate and Sertraline.

I'm experiencing a very odd tingling in the shoulders / spine region and loud noises / sudden eye movements cause temporary disorientation & an electrical-like tingle through my brain.

Anyone else?
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28 Male Married Actuary from Seattle
dx - Some combination of ADHD/Depression
Meds - 2x 100mg Sertraline / 1x 37.5mg Venlafaxine twice daily / 1x 10mg amphetamine / dextroamphetamine
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Old 08-17-10, 08:50 PM
jpr0 jpr0 is offline

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Re: ADHD Medication & Sertraline (Zoloft) & Mirtazapine (Remeron)

Hi Bayashi

I know this thread is 2 years old, but I just found your post searching google.
I made a username on here to ask you if you found the cause of your problem?
I was using sertraline too, 100mg once a day, for about 10 months. I recently stopped using them and switched to Mirtazaipe (I think?).

A few days before I switched I started getting similar sensations to what you describe. I have this "electrical" like tingling sensation, in my head, and limbs - and my head feels "fuzzy" in general. I've noticed that it is triggered by sharp eye movements or sharp sounds, but it occurs very frequently, and happens with any kind of body movement too. It's not painful, it's just a very annoying sensation. It kind of feels like the flu, without any fever, or aches.

Anyway, were you able to determine the cause of this? I'd love to know if you found anything.

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Old 08-25-10, 07:26 PM
Koblin3426 Koblin3426 is offline

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Re: ADHD Medication & Sertraline (Zoloft) & Mirtazapine (Remeron)

I'm on both of those medications (see my sig) and I've definitely noticed a very similar (I believe, the same) sensation since I've started on Remeron again. I don't get the head fuzz, but I did get some head pressure/sensations when I started Zoloft, but I haven't noticed any on Remeron. The head feeling went away with a few weeks of taking zoloft though.

That OTHER feeling though... I can't really describe it well but I feel like I know exactly what causes it. The feeling I get is exactly like the feeling you get from benadryll (especially if you take 2 or 3 which I don't recommend) where it's like this weakness/tingly feeling throughout your body. It's like it tickles sort of. It's also the same kind of feeling you get when you're about to slip on a wood floor with socks on (when your foot gets all tingly). I would definitely agree that while it's not painful, but it's certainly annoying (just like being tickled would be).

I had a hunch that the feeling was just the antihistamine in Remeron kicking in, as it's uncannily similar to the feeling I get from benadryll. A quick google search seems to validate my logic/intuition. Here's a quote from a website called crazymed (I put the link below too): "It also antagonizes the H1 histamine receptor (i.e. it's one hell of a central nervous system antihistamine, sort of like super Benadryl), which is a big reason why you get so tired and so hungry."
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Adderall - 10mg x 1-3 Mon-Fri [BARR]
Zoloft - 100mg x 1 [generic]
Remeron - 30mg x 1 [generic]
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