List of ADHD Medications - On-label and Off-label

[amu_d]

amu_d's list of possible ADHD medications - Along with notes, comments, suggestions, studies

Here I will list all the possible medications I find that might be useful in the treatment of ADHD/ADD and any related symptoms.

I will list notes, make comments, post studies. This will be done over a long period.

Notes:
- Feel free to make any comments you want. However, please don't derail the thread.
- I am NOT response for any injuries or death that result in anyone trying weird things without their doctor's approval.
- Feel free to ask any questions about my findings. I will respond soon, hopefully.
- I am not responsible for the ACCURACY of any statements. ALL NOTES AND COMMENTS ARE SUBJECTIVE (TO ME).
[Moderator edit by user request]
- I DO NOT ENCOURAGE THE USAGE OF STRICTLY ILLEGAL DRUGS
[Moderator edit by user request]
- This is my own list, so it doesn't mean what I list here is APPROVED for ADHD by the FDA. It might NOT be. Proceed with caution.

[amu_d]

I'll start with the common ADHD medications:

Stimulants:
Amphetamine-Based:
- Racemic Amphetamine
- Amphetamine Isomer
- Methamphetamine Isomer

Methylphenidate-Based:
- Racemic Methylphenidate
- Methylphenidate Isomer

Non-Stimulants:
- Strattera
- Wellbutrin
- Clonidine
- Guanfacine
- Provigil
- Tricyclics

[amu_d]

- Wellbutrin is good for inattention
- Clonidine and Guanfacine are good for hyperactivity/impulsivity and possibly memory

[amu_d]

Possible stimulants:
Cocaine
Nicotine
Caffeine
MDMA
KHAT
CYLERT
RACEMIC methamphetamine

Other:
Selegiline
Amantadine - Atypical Parkinson's Disease medication
EFFEXOR AND CYMBALTA - Due to action on Noradrenaline
Monoamine oxidase A inhibitors
Monoamine oxidase B inhibitors
DOPAMINE AGONISTS (SUCH AS PARKINSON's DISEASE MEDICATIONS)

[amu_d]

Dextromethamphetamine seems to be the best medication available for ADHD-PI and "SCT." A second best might be Dextroamphetamine

Dextromethylphenidate seems to be the best medication available for ADHD-C and ADHD-Predominatly Hyperactive. Methylphenidate as second best maybe. Cocaine and Nicotine would also be useful.

[amu_d]

Stimulants and Wellbutrin seem to increase anxiety
Tricyclics, Strattera, Guanfacine/Clonidine not so much

[amu_d]

Benzphetamine
Amineptine
Theobromine
Milnacipran
Reboxetine
Cannabis?

[amu_d]

Beta blockers to reduce bodyload on PNS created by stimulants
L-type calcium channel blockers to reduce stimulant-induced anxiety

SSRIs to handle comorbid depression
SSRIs or KLONOPIN to handle comorbid anxiety. Other benzos possible, but slow cognition a lot.

hmm...BuSpar and beta blockers might reduce stimulant-induced anxiety

[amu_d]

Obscure stimulants:

Originally Posted by hmmm.....

N,N-Dimethylamphetamine is a stimulant drug related to other amphetamines such as methamphetamine.
Dimethylamphetamine has weaker stimulant effects than amphetamine or methamphetamine and is considerably less addictive^[1] and less neurotoxic compared to methamphetamine.^[2][3] However it still retains some mild stimulant effects and abuse potential,^[4] and is a Schedule I controlled drug.
Dimethylamphetamine has occasionally been found in illicit methamphetamine laboratories, but is usually an impurity rather than the desired product. It may be produced by accident when methamphetamine is synthesised by methylation of amphetamine if the reaction temperature is too high or an excess of methylating agent is used.

Phenmetrazine
Ethylamphetamine
4-Methyl-aminorex
Methcathinone
Cathinone
Fenethylline
Aminorex
Benzylpiperazine

More:
Diethylcathinone
Dimethylcathinone
Phentermine
Sibutramine
Crack Cocaine


Don't worry, effectiveness of obscure stimulants for ADHD will be discussed eventually.

[Contrapunctus]

Pyrovalerone and Prolintane look like good possible ADHD meds (relatively long lasting DARI/NERI's). Pyrovalerone is still available in the US, and it is a C-V medication! Unfortunately, I have never heard of it being prescribed for any purpose.

Also, diethylpropion (Tenuate) could possibly be used for ADHD. Aminorex would also be a good treatment for ADHD, having good ratios of NE/DA. 4-methyl-aminorex is less potent by weight when compared to Aminorex, but may have unique pharmacological properties. From my experience with Pemoline (cylert), I found that the oxazoline class had a very low incidence of side-effects, as well very little efficacy as an anorectic (which is good!). It was certainly the most "nootropic" of the stimulants.

[amu_d]

Good find Contrapunctus. Unfortunately, Pemoline isn't used much. It is still available as a generic, although Brand-name Pemoline "Cylert" has been discontinued. I haven't found pemoline's effect on the liver to be so concerning. Many others have similar effects. My feeling is it should be used a lot, with careful monitoring of the liver.

[amu_d]

Off-label: 1000 raw Banana peels. Jus kidding

[amu_d]

Another good possible medication:
Maprotiline

[speedo]

don't forget sudafed and caffiene

[amu_d]

Originally Posted by speedo

don't forget sudafed and caffiene

I got caffiene in post 4

Good reminder about sudafed. I just hope sudafed PE (which doesn't contain pseudoephedrine) doesn't replace the original one. Otherwise, the original will be discontinued.