How much drugs are too much?

[Hobbledehoy]

10 mg Lexapro
4 mgs of Klonopin
30-60 mgs of Adderall
100-300 mg Wellbutrin XR
300-600 mg of Seroquel

This is only a hypothetical concoction. That I don't even know if my pdoc will agree with.

I already take four of the five (minus the Wellbutrin). And the Klonopin/Adderall mix makes me Obama at work. Though this is not at 4 mgs, but 2 mgs of Klonopin and 30 mgs of Adderall (1 klon with each 15 mg of Addy) with gaps (insecurity/wear-offs) inbetween.

And then I suffer from extreme depression at home until I take my 300 mgs of Seroquel which relieves it, but knocks me the hell out. I usually cut the 300 into little pieces and transition into sleep.

But in this dream line-up, I think I can avoid the gaps and the depression at home.

The only thing I fear is the increased anxiety from the Wellbutrin (10:1 Norepinephrine: Dopamine) which is the same as the levoamphetamine part of the Adderall.

But the increase in Klonopin from 4 mgs should cover this, just as the 2 mgs of Klonopin covers the 30 mgs of Adderall. I wouldn't need Klonopin if I didn't suffer from performance anxiety which Adderall seems to exacerbate. Plus I have overanalytical thoughts that gets in the way of focus which stems from some Asperger's type traits. Klonopin works for that.

I know I have dopamine based depression along with serotonin deficiency. I am Bipolar and fear mania. But my research shows that Klonopin is actually treatment of mania. And of course, Seroquel is also. It took me out of psychosis.

My lexapro hasn't kicked in yet, so I don't know what my Adderall increased is going to have to be. Probably double, unless the Wellbutrin can do the trick keeping the addictive Schedule II at it's minimum.

Klonopin, I just found is a Schedule IV, so I think of it as just candy now. I'm in for the long run for this drug as it has changed my anxiety ridden life.

I'm willing to do anything to succeed and avoid this damn near suicidal depression (depletion) I get at night. I'm not suicidal, so don't worry. But I get obsenely self-defeatist.

I'm going to give the Lex 1 more week as it needs two just to feel an ounce of effects.

But how many drugs are too much? Have you heard of a person(s) that were on a coctail of five drugs?




All of these people who talk about weaning off of drugs, I don't understand. If anything, if I experience poop out, I would look to switch to an equivalent. My life before drugs sucked you know what (multiple body parts). And I do not regret who I've become. I'm productive and competing on my white collar job. I am not willing to go back to my life without drugs. See my old symptoms below:

• Poor Memory/forgetfulness (can't remember college).
• Constant Worry
• Fear of disapproval
• Overanalyzing, even over little things
• Nothing is ever good enough
• Worsening lack of interest in things once enjoyed
• Compulsive and addictive personality (masturbation, video games, ex porn addict, etc.)
• Paranoia, especially in social environments
• Trouble recalling vocabulary unless focused
• Excessive nail biting, pacing
• Anxiety is aggravated after video games, alleviated during.
• Burning sensation of the mind (fish oil and nose breathing alleviates the problem.
• Can't work on little sleep. All symptoms become worse.
• Zero friends.
• Receives energy from positive environments (college), but drained by negative ones (work).
• Easily manipulated due to my empathy.
• Feeling of omniscience between wake and sleep state.
• Constantly dreading the little I do say.
• Overfocused on bodily noises.
• Trouble seeing the little details on contracts and accounting records.
• Constant need of reinforcement.
• Daydreams during meetings, school, and home of what can be.
• Trouble shifting from one task to another.
• Must force myself into a focus mode to talk to the public or get boring things done.

This illness comes from my father's side and none of the siblings succeeded in finding a piece of mind, a stable job, a functional family, etc. Again, my uncle chopped his head off under a 18 wheeler truck while drunk. My aunt is morbidly obese and unemployed. And I don't want to go into my father's problems, but he has not won the stability battle either. They are all dependent on their own individuals. My father my mother until the divorce. And I don't want to be a hypocrite because I haven't walked in their shoes.

I know I sound like a broken record or a childish 20'ish with my story, but I've got to get this right. I don't care about dependency and addiction (probably not in my case). Death by toxicity, maybe.

But I'm sure some of you are on a bunch, right? I'm just confirming. I'm on the right track with the Klon/Addy Combo, but need to extend the effects as constructively as possible.

I put an embarrassed icon as I come to you as a humble no nothing.

[indy]

do you think you get depression at night from your adderall wearing off? that's what was happening to me and my psych came up with an ingenious way of fixing it. at 5pm i take 100mg wellbutrin SR cut in half to destroy the SR coating. this effectively gives me immediate release wellbutrin which kicks in as my adderall is wearing off and prevents the depression that comes along with stimulant crash (at least for me.)

other than that, here is my cocktail (i'm bipolar, OCD and ADHD)

AM
200mg lamictal (mood stabilizer)
50mg zoloft (ssri antidepressant)
150mg wellbutrin sr (adjunct adhd treatment)
20mg adderall xr (adhd treatment)
1PM
20mg zeldox/geodon (antipsychotic)
25mg adderall xr (adhd treatment)
5PM
100mg wellbutrin sr, cut in half (prevents adderall crash)
PM
60mg zeldox/geodon (antipsychotic)
1.5mg clonazepam/klonopin (anxiolytic)

so that would make me on 6 different drugs with some taken multiple times a day.

[ecu20]

Originally Posted by Hobbledehoy

10 mg Lexapro
4 mgs of Klonopin
30-60 mgs of Adderall
100-300 mg Wellbutrin XR
300-600 mg of Seroquel

This is only a hypothetical concoction. That I don't even know if my pdoc will agree with.

I already take four of the five (minus the Wellbutrin).

Hypothetically, that's not the type of concoction I would recommend anyone to take. I understand that many people are on those many drugs, but honestly most of your mix interferes with the effects of the other drugs.

For example, look at these comparisons:

Seroquel
-Antagonistic activity at dopamine, serotonin, norepinephrine, alpha-andrenergic, and histamine receptors.
-This works against all effects of Lexapro, Adderall, and Wellbutrin.

Adderall
-Stimulates release of dopamine, norepinephrine and serotonin into the synaptic cleft.
-Dopamine, norepinephrine and (weak) serotonin reuptake inhibitor.

Lexapro
-Acts as a serotonin reuptake inhibitor.

Wellbutrin
-dopamine and norepinephrine reuptake inhibitor. Also a nicotinic antagonist (but not too important here).


Basically, you are using adderall which stimulates release of these neurotransmitters into the synaptic cleft. Then adderall, lexapro, and wellbutrin each act as reuptake inhibitors meaning the neurotransmitters don't get "cleared" and brought back up into the neuron, increasing the already high levels of the 3 neurotransmitters.

Then you add in seroquel which comes in and blocks all those neurotransmitters from connecting with and stimulating their respective receptor. Klonopin furthers seroquels "inhibiting" action by connecting to gaba receptors and potentiating GABA which lowers neuronal firing strength and frequency.

I just see it as a very rough and complex pharmaceutical "speedball" in a simple vague sense, it brings up neurotransmitter levels just to block them from their receptors all while lowering brain activity by reducing neuron firing (in strength and frequency).

This is the best way I could describe it, lemme know if a picture of this would help explain it.

[Yellow]

what your takin

[Hobbledehoy]

Originally Posted by indy

do you think you get depression at night from your adderall wearing off? that's what was happening to me and my psych came up with an ingenious way of fixing it. at 5pm i take 100mg wellbutrin SR cut in half to destroy the SR coating. this effectively gives me immediate release wellbutrin which kicks in as my adderall is wearing off and prevents the depression that comes along with stimulant crash (at least for me.)

other than that, here is my cocktail (i'm bipolar, OCD and ADHD)

AM
200mg lamictal (mood stabilizer)
50mg zoloft (ssri antidepressant)
150mg wellbutrin sr (adjunct adhd treatment)
20mg adderall xr (adhd treatment)
1PM
20mg zeldox/geodon (antipsychotic)
25mg adderall xr (adhd treatment)
5PM
100mg wellbutrin sr, cut in half (prevents adderall crash)
PM
60mg zeldox/geodon (antipsychotic)
1.5mg clonazepam/klonopin (anxiolytic)

so that would make me on 6 different drugs with some taken multiple times a day.

Ha ha. I was just fighting you in another thread. And you give me the best advice/confirmation anyone could give me in another. So lets just call you indy2. THough, you may not know yet.

That's the exact same reason why I'm hitting depression. Adderall is wearing off. Wellbutrin did seem like an answer.

[Hobbledehoy]

Bipolar ADHD GAD OCD is complicated ecu20.

[indy]

Originally Posted by Hobbledehoy

Ha ha. I was just fighting you in another thread. And you give me the best advice/confirmation anyone could give me in another. So lets just call you indy2. THough, you may not know yet.

That's the exact same reason why I'm hitting depression. Adderall is wearing off. Wellbutrin did seem like an answer.

i don't remember fighting with you... how's that for adhd? besides, i don't "fight" with people online... i may debate my point, but i leave emotions out of it.

make sure you cut the wellbutrin up so it only acts during the evening and doesn't keep you up at night. also "immediate release" wellbutrin increases the chance that one could have a seizure, that's why the SR and XL versions are mainly prescribed. but once a day and in conjunction with my mood stabilizer which is an anti-seizure med, and my psych decided to try it out. i haven't had a seizure.

glad i could help.

also, the guy who gave you the pharmacological rundown is right but he neglected to state which neuronal receptors are affected by each drug and the relative affinities for such receptors of each drug. that's why i can take an antipsychotic and a stimulant at the same time and have them both work. they aren't mutually exclusive. i can also take klonopin and my stimulant still works. so YMMV.

so... what thread were we arguing in? most likely i've forgotten all about it.

it should also be noted that with the cocktail i mentioned above i have effectively been in bipolar remission for months now and my ocd has been reduced to mere quirkiness. in addition my adhd is very well managed. so yeah, it can be done with polypharmacy.

[ecu20]

Originally Posted by Hobbledehoy

Bipolar ADHD GAD OCD is complicated ecu20.

I understand that comorbidities will complicate treatment for some, but for most, it should not be necessary to stack 3,4,5 plus drugs. "pharmaceutical speedballs" are what I call it, people begin to take more and more drugs in an attempt to minimize the negative side effects of the initial drugs, potentially resulting in fatal or serious drug interaction complications, and certainly increases the likelihood of drug dependence to the point of addiction. I speak about comorbid conditions and treatments from my experiences and by talking to other people in the same boat, don't be so quick to assume i've never walked in steps similar to yours .

You need to take a close look at each drug, it's purpose, and why you're taking it.

I already take four of the five (minus the Wellbutrin). And the Klonopin/Adderall mix makes me Obama at work. Though this is not at 4 mgs, but 2 mgs of Klonopin and 30 mgs of Adderall (1 klon with each 15 mg of Addy) with gaps (insecurity/wear-offs) inbetween.

And then I suffer from extreme depression at home until I take my 300 mgs of Seroquel which relieves it, but knocks me the hell out. I usually cut the 300 into little pieces and transition into sleep.

But in this dream line-up, I think I can avoid the gaps and the depression at home.

The only thing I fear is the increased anxiety from the Wellbutrin (10:1 Norepinephrine: Dopamine) which is the same as the levoamphetamine part of the Adderall.

But the increase in Klonopin from 4 mgs should cover this, just as the 2 mgs of Klonopin covers the 30 mgs of Adderall. I wouldn't need Klonopin if I didn't suffer from performance anxiety which Adderall seems to exacerbate. Plus I have overanalytical thoughts that gets in the way of focus which stems from some Asperger's type traits. Klonopin works for that.

I know I have dopamine based depression along with serotonin deficiency. I am Bipolar and fear mania. But my research shows that Klonopin is actually treatment of mania. And of course, Seroquel is also. It took me out of psychosis.

My lexapro hasn't kicked in yet, so I don't know what my Adderall increased is going to have to be. Probably double, unless the Wellbutrin can do the trick keeping the addictive Schedule II at it's minimum.

Klonopin, I just found is a Schedule IV, so I think of it as just candy now. I'm in for the long run for this drug as it has changed my anxiety ridden life.

Taking a whopping 4mg of clonazepam with 30-60mg of amphetamine to be "obama" at work is not an appropriate medical use of benzodiazapines, they should only be used in the initial period of treating mania or with acute psychotic episodes requiring high levels of sedation. It should not be used to soften the edges of anxiety that is exasperated by a stimulant.

Clonazepam is a schedule IV, and it concerns me you would think of it as "just candy now." Ask anyone who has been physically dependent on a benzodiazapine, it can happen quickly and WILL happen if used often enough, especially on a daily basis. It's a physical addiction much like opiate addiction, and can cause serious problems if discontinued without slowly tapering off.

Based on what I have read, you have not extensively researched the pharmacological aspects of these drugs, which is no offense or insult to you whatsoever. It just seems like your explanations behind using each medication for what is a a bit spotty and inaccurate.


---------------------


Indy is correct i didn't specify each drug's specific interactions such as receptor subtypes, receptor affinity of each respective ligand, neuronal pathways activated/used by each drug, etc etc, I was trying to keep it simple for those not versed in drug pharmacology/pharmacokinetics, and I don't have the free time to waste to copy and paste all the sepecifics for each drug, you can easily find journal entries on the pharmacodynamics of these drugs online.

However, should you have a specific point to address i'd be more than happy to discuss it with ya .

[KMiller]

Originally Posted by ecu20

Hypothetically, that's not the type of concoction I would recommend anyone to take. I understand that many people are on those many drugs, but honestly most of your mix interferes with the effects of the other drugs.

You're oversimplifying the mechanisms of actions based on what they theoretically do, versus what clinical experience tells us. For some reason, antipsychotics and stimulants can be taken together and both can work at the same time. For example, I take Adderall and Geodon together. Antipsychotics and Wellbutrin also have a good track record together; I take Wellbutrin as well. And I'm not just using myself for clinical experience; many, many children at the hospital where I worked had a combination like Ritalin and Risperdal or Adderall and Zyprexa, etc.

I personally have wrestled with the question of why these are able to be taken together without canceling one another, as they should in theory, and come up empty handed; the best explanation is simply that we don't know why they can all work together, but they do.

The weak points of this particular concoction are that Seroquel at 300mg is a **** poor antipsychotic, as it has a much higher affinity for H1 than it does for D2 or 5-HT2A. So adding three drugs that can potentiate mania (Adderall, Lexapro, and, weakly, Wellbutrin) may be more than that particular antipsychotic can handle. So it would need to be 600mg.

Also, the Adderall is likely the major cause of the problems. It's the weak link that needs to go. Using Klonopin to control mood swings associated with stimulant withdrawal is pretty silly, when it's far better to simply not take the stimulant in the first place.

I agree with you, however, that Hobbledehoy demonstrates a pretty poor understanding of how these drugs work together and his attitude here is all wrong.

[ecu20]

Originally Posted by KMiller

You're oversimplifying the mechanisms of actions based on what they theoretically do, versus what clinical experience tells us. For some reason, antipsychotics and stimulants can be taken together and both can work at the same time. For example, I take Adderall and Geodon together. Antipsychotics and Wellbutrin also have a good track record together; I take Wellbutrin as well. And I'm not just using myself for clinical experience; many, many children at the hospital where I worked had a combination like Ritalin and Risperdal or Adderall and Zyprexa, etc.

I personally have wrestled with the question of why these are able to be taken together without canceling one another, as they should in theory, and come up empty handed; the best explanation is simply that we don't know why they can all work together, but they do.

Here's another oversimplification on my part: You are correct that antipsychotics and stimulants can be taken together and can both work. HOWEVER, THERE ARE 2 DIFFERENT TYPES OF ANTIPSYCHOTICS: Typical (can cause tardive dyskinesia related extrapyramidal side effects) and Atypical (extremely lowered risk of extrapyramidal sides).

Typical antipsychotics are 1st generation antipsychotic drugs that have a characteristic of non-selective d2 receptor antagonistic effects in the 4 dopaminergic pathways, namely the mesolimbic pathway which is thought to be the culprit of initiating psychotic events.

Atypical antipsychotics are a newer, 2nd generation antipsychotic drug that primarily work on the serotonin and dopamine receptors, but can work on other receptor-ligand interactions. The difference that sets them apart from typical antipsychotics is that atypicals have an extremely reduced rate of occurrences of extrapyramidal side effects, in part due to the lesser affinity of d2 receptors. They generally have increased affinity of d4 receptors, but the jury is still out on the theory that d4 receptors are similar to d2 in exerting antipsychotic effects.

[indy]

Originally Posted by ecu20

Here's another oversimplification on my part: You are correct that antipsychotics and stimulants can be taken together and can both work. HOWEVER, THERE ARE 2 DIFFERENT TYPES OF ANTIPSYCHOTICS: Typical (can cause tardive dyskinesia related extrapyramidal side effects) and Atypical (extremely lowered risk of extrapyramidal sides).

what does this have to do with anything? both seroquel and the antipsychotic i mentioned (zeldox/ziprasidone) are atypical antipsychotics. so why mention typical versus atypical? your point is moot.

[indy]

Originally Posted by ecu20

I understand that comorbidities will complicate treatment for some, but for most, it should not be necessary to stack 3,4,5 plus drugs. "pharmaceutical speedballs" are what I call it, people begin to take more and more drugs in an attempt to minimize the negative side effects of the initial drugs, potentially resulting in fatal or serious drug interaction complications, and certainly increases the likelihood of drug dependence to the point of addiction. I speak about comorbid conditions and treatments from my experiences and by talking to other people in the same boat, don't be so quick to assume i've never walked in steps similar to yours .

You need to take a close look at each drug, it's purpose, and why you're taking it.

drug's specific interactions such as receptor subtypes, receptor affinity of each respective ligand, neuronal pathways activated/used by each drug, etc etc, I was trying to keep it simple for those not versed in drug pharmacology/pharmacokinetics, and I don't have the free time to waste to copy and paste all the sepecifics for each drug, you can easily find journal entries on the pharmacodynamics of these drugs online.

However, should you have a specific point to address i'd be more than happy to discuss it with ya .

who are you and why are you giving out medical advice? i believe hobbledehoy asked for it, so i won't push that question but still... do you have a degree in psychopharmacology? an M.D.?

i resent the fact that you refer to anybody taking multiple medications as taking a medication "speedball" that likens me to the kind of people i don't and shouldn't be associated with. i've never done recreational drugs in my life. (never needed to... i can get high from mania all on my own.)

i will have you know that after taking 6 medications, each added one by one by my psychiatrist over the course of a year, i have been in bipolar "remission" for over 6 months. this is phenomenal considering i've lost my entire 20s to this illness. for the first time in a decade, i am "normal." boringly so, actually. and none of the medications i take are taken to control side effects from other medications. they all simply co-exist to make me healthy and functional.

i agree that hobbledehoy's reasons for taking so much klonopin sound a little unreasonable. if anybody needs that much klonpin they need to adjust their medication profile. but taking klonopin shouldn't be frowned upon. i have taken it (from 1mg to 4 mgs) for the last 5 years and while i am totally physically dependent on it (AS I AM ON MOST OF MY MEDS... just ask me about it when i've skipped a dose) that isn't an issue because i don't plan on going off it and if i do i will taper down over the course of about 6 months. (i've done it that way before.)

first, if you are going to hand out medical advice then i'd like to know your credentials and second you oversimplify things to make your point when people like me function very well on medication that would seem contradictory.

if you are going to hand out such advice then you SHOULD include which receptors and affinities for the receptors each medication hits, so that we can counter with the fact that yes, these meds can all be taken together.

you also don't mention biological half-lives. i take my largest dose of antipsychotic at night as it has a 7 hour half-life, and take a small dose mid-day. this leaves enough in my system for effective symptom control while not countering my daytime meds in the slightest. at least not in the ways you think. the only thing that happens is i don't get manic from adderall, but it still works to treat ADHD. i also take clonazepam at night which can't be justified as nicely as it has a 36 hour (or so) half-life. but as i've been on it so long i am very much at steady state and thus my clonazepam spike happens at night before sleeping, this works very well for me.

also you fail to note the conditions from which we suffer. i have both ADHD and OCD, now tell me how that is possible? oh, but it is. one in burried deep in the limbic system and one involved the prefrontal cortext. this just proves things are not as straight forward as they seem and thus supports the idea that polypharmacy works, as different meds are able to treat comorbid conditions effectively, while not cancelling each other out. wouldn't it be nice if my ADHD cancelled my OCD... but it doesn't work that way.

anyway... please refrain from using common recreational drug language to those of us that have to be subject to polypharmacy just to live normal lives. that is demeaning, rude and undermines the serious of our mental illnesses. for me, it's either i take my "speed ball" or spend most of my life bouncing in and out of psych wards. and that's no way to live.

[indy]

Originally Posted by KMiller

You're oversimplifying the mechanisms of actions based on what they theoretically do, versus what clinical experience tells us. For some reason, antipsychotics and stimulants can be taken together and both can work at the same time. For example, I take Adderall and Geodon together. Antipsychotics and Wellbutrin also have a good track record together; I take Wellbutrin as well. And I'm not just using myself for clinical experience; many, many children at the hospital where I worked had a combination like Ritalin and Risperdal or Adderall and Zyprexa, etc.

I personally have wrestled with the question of why these are able to be taken together without canceling one another, as they should in theory, and come up empty handed; the best explanation is simply that we don't know why they can all work together, but they do.

The weak points of this particular concoction are that Seroquel at 300mg is a **** poor antipsychotic, as it has a much higher affinity for H1 than it does for D2 or 5-HT2A. So adding three drugs that can potentiate mania (Adderall, Lexapro, and, weakly, Wellbutrin) may be more than that particular antipsychotic can handle. So it would need to be 600mg.

Also, the Adderall is likely the major cause of the problems. It's the weak link that needs to go. Using Klonopin to control mood swings associated with stimulant withdrawal is pretty silly, when it's far better to simply not take the stimulant in the first place.

I agree with you, however, that Hobbledehoy demonstrates a pretty poor understanding of how these drugs work together and his attitude here is all wrong.

in hobbledehoy's case if he were to take seroquel XR then he'd most likely be able to avoid so much clonazepam as he'd get the anxiolytic effect of the seroquel during the day. that might help him out. yeah, i agree, unless you are bipolar II or just aren't prone to wild manias seroquel isn't going to do much. it does help with sleep which can have its own antimanic effects so maybe hobbledehoy needs it for this.

[Hobbledehoy]

I'm not even going to go into the inconsistencies that eco20 and KMiller present.

I was called a Silly Lamb by God today, as it was tattooed on the right fender bender of a Camry. Yeah, I'm Schizo. Then I got to work and got an email about anger and how to sort it out, in Biblical context. It was nice. I won't share it since I already push the envelope.

But most of which they say is based on ego, a great attempt at feeling better about yourself.

I deal with Attention Deficit Disorder, Social Anxiety Disorder, General Anxiety Disorder, Manic Depression, Asperger's (undiagnosed but sure), and Obsessive Compulsive Disorder.

I started the Lexapro because I became everything I wanted on the outside, but nothing I wanted in the inside. I was a working machine that didn't know when to stop. The Lex is already helping me stop to smell the roses, but at the expense of the effects of the Adderall. The Serotonin-Dopamine relationship.

I take Adderall because I have ADD. I take Seroquel at night (300mgs) because I have manic depression. 300mgs is suggested for the depression side and 600mgs is suggested for mania. I am well aware of this. I don't take Seroquel during the day since it makes me catatonic and I don't even believe the Adderall has the chutzpah to keep me alert. Remember, I am not manic during the day so it causes intense drowsiness. It does wonders for the depression though. That is, 10 seconds before it puts you to sleep.

Now, as all we reasonable people know, Adderall can exacerbate anxiety. But why do we continue to take Adderall? Because we have ADD. The Klonopin seems to take the edge off of the anxiety, making socializing and focusing possible simutaneously. Again, the klonopin deletes the overalyzing of social mistakes. And Adderall does it part too. But it CAN spur a panic attack without the Klonopin. So this is why I take it and I take it without the negative stigma eco20 holds. I take it with 15 mgs of Adderall and become functional, for 3.5 hours.

But the problem is that the Adderall only lasts a full 3 to 3.5 hours. And there are gaps inbetween and I become depressed in gaps between my next dosage.

Arguing that Seroquel and Adderrall can't be taken together is seemingly comical. Because I am on the two and they don't cancel each other out. So I can speak from experience.

So on to what I'm dealing with. Gaps in the day when the Adderall wears off, causing depression and ill-focus. And then massive depression when I come home. I do just take the Seroquel, but even chopping a 300 mg pill into pieces of 37.5 makes me drowsy. And I do want to enjoy the evening. Thank you.

So I have two choices as I hit the two week mark of the Lexapro. Increase the Adderall dosage to 60 mgs and the Klonopin to 3-4. I say three because when I take Adderall at home, I don't have panic attacks. Because I live in my own household. But I need something to hold me off during the night. Because if one thing goes wrong (self-identified social error) at work, it causes massive depression at home.

So it will be nice to add wellbutrin since it does the same thing as Adderall and lasts throughout the entire day. Taking Klonopin to even the mixture out is not crazy. The Wellbutrin may bring anxiety but will bring depression relief. And I am not afraid of dependency.

You guys are talking to people who are perfecting the process to become functional.

I wouldn't have a job if it weren't for benzos. And they were introduced to me by Him just in time. And I wouldn't be able to focus without Adderall. And I wouldn't be able to socialize if it weren't for Klon. And I would be depressed if it weren't for Adderall.

So if I know that Klonopin/Adderall brings me to the point I need to be.

Adding Wellbutrin and one to two more klonopins sounds like a reasonable plan.

If Wellbutrin is not given to me, I sure in the hell have to get upped to 60mgs of Adderrall and 4 mgs of Klonopin.

Don't put us down for what works for us. That's being a hypocrite.

My job is probably the most difficult, boring, and tediously painstaking one out there.

And I'm going to keep doing what I'm doing. Very methodical. And continue to succeed.

[Hobbledehoy]

And I do need Seroquel to sleep.